Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IAD8_LEIIN

TriTrypDb:

LINF_340044600

Length:

183

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Show entries

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005930	axoneme	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A4IAD8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IAD8

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	119	121	PF00675	0.484
CLV_NRD_NRD_1	127	129	PF00675	0.432
CLV_NRD_NRD_1	131	133	PF00675	0.412
CLV_NRD_NRD_1	77	79	PF00675	0.476
CLV_NRD_NRD_1	81	83	PF00675	0.564
CLV_PCSK_KEX2_1	119	121	PF00082	0.566
CLV_PCSK_KEX2_1	77	79	PF00082	0.490
CLV_PCSK_KEX2_1	81	83	PF00082	0.588
CLV_PCSK_PC7_1	77	83	PF00082	0.549
CLV_PCSK_SKI1_1	107	111	PF00082	0.608

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P774	Leptomonas seymouri	61%	100%
A0A0S4J6R9	Bodo saltans	28%	98%
A0A0S4KRE5	Bodo saltans	28%	100%
A0A1X0PA28	Trypanosomatidae	37%	100%
A0A3Q8IIW0	Leishmania donovani	99%	100%
A0A3R7M5H7	Trypanosoma rangeli	37%	92%
A4HB90	Leishmania braziliensis	76%	100%
C9ZLV7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
E9B5G2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4Q2H3	Leishmania major	88%	100%

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