Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Secreted protein

Gene product:

hypothetical protein - unknown function

Species:

Leishmania infantum

UniProt:

A4IAA7_LEIIN

TriTrypDb:

LINF_340041050

Length:

121

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IAA7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IAA7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	40	42	PF00675	0.533
CLV_NRD_NRD_1	61	63	PF00675	0.556
CLV_NRD_NRD_1	79	81	PF00675	0.541
CLV_PCSK_FUR_1	57	61	PF00082	0.563
CLV_PCSK_KEX2_1	40	42	PF00082	0.533
CLV_PCSK_KEX2_1	59	61	PF00082	0.560
CLV_PCSK_KEX2_1	81	83	PF00082	0.535
CLV_PCSK_PC1ET2_1	59	61	PF00082	0.560
CLV_PCSK_PC1ET2_1	81	83	PF00082	0.535
CLV_PCSK_PC7_1	57	63	PF00082	0.560
CLV_PCSK_SKI1_1	116	120	PF00082	0.704
CLV_PCSK_SKI1_1	40	44	PF00082	0.567
CLV_PCSK_SKI1_1	61	65	PF00082	0.553
CLV_PCSK_SKI1_1	99	103	PF00082	0.545
DOC_MAPK_FxFP_2	26	29	PF00069	0.485
DOC_PP4_FxxP_1	26	29	PF00568	0.485
DOC_PP4_FxxP_1	91	94	PF00568	0.502
DOC_USP7_MATH_1	13	17	PF00917	0.425
LIG_14-3-3_CanoR_1	25	29	PF00244	0.498
LIG_14-3-3_CanoR_1	40	50	PF00244	0.588
LIG_14-3-3_CanoR_1	80	85	PF00244	0.529
LIG_14-3-3_CterR_2	116	121	PF00244	0.566
LIG_BIR_II_1	1	5	PF00653	0.473
LIG_BRCT_BRCA1_1	91	95	PF00533	0.505
LIG_FHA_2	34	40	PF00498	0.573
LIG_LIR_Apic_2	23	29	PF02991	0.478
LIG_LIR_Apic_2	90	94	PF02991	0.506
LIG_LIR_Nem_3	10	14	PF02991	0.420
LIG_PDZ_Class_1	116	121	PF00595	0.566
LIG_Pex14_2	87	91	PF04695	0.521
LIG_SH2_STAT5	88	91	PF00017	0.519
LIG_SH3_1	111	117	PF00018	0.560
LIG_SH3_3	111	117	PF00018	0.594
LIG_SUMO_SIM_par_1	4	10	PF11976	0.413
LIG_WRC_WIRS_1	8	13	PF05994	0.419
LIG_WRC_WIRS_1	88	93	PF05994	0.511
MOD_CK2_1	33	39	PF00069	0.568
MOD_GlcNHglycan	66	69	PF01048	0.556
MOD_GlcNHglycan	99	102	PF01048	0.541
MOD_GSK3_1	29	36	PF00069	0.500
MOD_GSK3_1	76	83	PF00069	0.649
MOD_NEK2_1	1	6	PF00069	0.432
MOD_NEK2_1	7	12	PF00069	0.407
MOD_NEK2_1	87	92	PF00069	0.709
MOD_PKA_1	40	46	PF00069	0.579
MOD_PKA_1	80	86	PF00069	0.523
MOD_PKA_2	24	30	PF00069	0.523
MOD_PKA_2	40	46	PF00069	0.551
MOD_Plk_4	7	13	PF00069	0.418
TRG_DiLeu_BaLyEn_6	3	8	PF01217	0.417
TRG_ENDOCYTIC_2	88	91	PF00928	0.633
TRG_ER_diArg_1	60	62	PF00400	0.564
TRG_NLS_MonoCore_2	58	63	PF00514	0.558
TRG_NLS_MonoExtN_4	57	63	PF00514	0.560

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IHG7	Leishmania donovani	99%	100%