Glycolipid biosynthesis, Lipophosphoglycan biosynthetic (Lpg2) LPG2
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 11 |
| NetGPI | no | yes: 0, no: 11 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0000139 | Golgi membrane | 5 | 12 |
| GO:0016020 | membrane | 2 | 12 |
| GO:0031090 | organelle membrane | 3 | 12 |
| GO:0098588 | bounding membrane of organelle | 4 | 12 |
| GO:0110165 | cellular anatomical entity | 1 | 12 |
| GO:0005737 | cytoplasm | 2 | 1 |
| GO:0005794 | Golgi apparatus | 5 | 1 |
| GO:0043226 | organelle | 2 | 1 |
| GO:0043227 | membrane-bounded organelle | 3 | 1 |
| GO:0043229 | intracellular organelle | 3 | 1 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 1 |
Related structures:
AlphaFold database: A4IA88
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0001817 | regulation of cytokine production | 4 | 1 |
| GO:0001818 | negative regulation of cytokine production | 5 | 1 |
| GO:0002577 | regulation of antigen processing and presentation | 4 | 1 |
| GO:0002578 | negative regulation of antigen processing and presentation | 5 | 1 |
| GO:0002682 | regulation of immune system process | 3 | 1 |
| GO:0002683 | negative regulation of immune system process | 4 | 1 |
| GO:0009605 | response to external stimulus | 2 | 1 |
| GO:0009607 | response to biotic stimulus | 2 | 1 |
| GO:0009892 | negative regulation of metabolic process | 4 | 1 |
| GO:0010468 | regulation of gene expression | 5 | 1 |
| GO:0010605 | negative regulation of macromolecule metabolic process | 5 | 1 |
| GO:0010629 | negative regulation of gene expression | 6 | 1 |
| GO:0019222 | regulation of metabolic process | 3 | 1 |
| GO:0032655 | regulation of interleukin-12 production | 5 | 1 |
| GO:0032695 | negative regulation of interleukin-12 production | 6 | 1 |
| GO:0043207 | response to external biotic stimulus | 3 | 1 |
| GO:0044403 | biological process involved in symbiotic interaction | 2 | 1 |
| GO:0044419 | biological process involved in interspecies interaction between organisms | 1 | 1 |
| GO:0048519 | negative regulation of biological process | 3 | 1 |
| GO:0050789 | regulation of biological process | 2 | 1 |
| GO:0050896 | response to stimulus | 1 | 1 |
| GO:0051239 | regulation of multicellular organismal process | 3 | 1 |
| GO:0051241 | negative regulation of multicellular organismal process | 4 | 1 |
| GO:0051701 | biological process involved in interaction with host | 3 | 1 |
| GO:0051707 | response to other organism | 2 | 1 |
| GO:0052173 | response to defenses of other organism | 3 | 1 |
| GO:0052200 | response to host defenses | 4 | 1 |
| GO:0052553 | modulation by symbiont of host immune response | 6 | 1 |
| GO:0052572 | response to host immune response | 5 | 1 |
| GO:0060255 | regulation of macromolecule metabolic process | 4 | 1 |
| GO:0065007 | biological regulation | 1 | 1 |
| GO:0075136 | response to host | 3 | 1 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005215 | transporter activity | 1 | 12 |
| GO:0005338 | nucleotide-sugar transmembrane transporter activity | 4 | 12 |
| GO:0005458 | GDP-mannose transmembrane transporter activity | 6 | 12 |
| GO:0015932 | nucleobase-containing compound transmembrane transporter activity | 3 | 12 |
| GO:0022857 | transmembrane transporter activity | 2 | 12 |
| GO:0036080 | purine nucleotide-sugar transmembrane transporter activity | 5 | 12 |
| GO:1901505 | carbohydrate derivative transmembrane transporter activity | 3 | 12 |
| GO:0015291 | secondary active transmembrane transporter activity | 4 | 1 |
| GO:0015297 | antiporter activity | 5 | 1 |
| GO:0022804 | active transmembrane transporter activity | 3 | 1 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_PCSK_SKI1_1 | 149 | 153 | PF00082 | 0.463 |
| CLV_PCSK_SKI1_1 | 174 | 178 | PF00082 | 0.226 |
| CLV_PCSK_SKI1_1 | 224 | 228 | PF00082 | 0.396 |
| DEG_MDM2_SWIB_1 | 239 | 247 | PF02201 | 0.396 |
| DEG_Nend_UBRbox_3 | 1 | 3 | PF02207 | 0.596 |
| DOC_CYCLIN_RxL_1 | 73 | 81 | PF00134 | 0.401 |
| DOC_CYCLIN_yClb5_NLxxxL_5 | 107 | 113 | PF00134 | 0.378 |
| DOC_CYCLIN_yCln2_LP_2 | 196 | 202 | PF00134 | 0.267 |
| DOC_MAPK_gen_1 | 75 | 82 | PF00069 | 0.414 |
| DOC_MAPK_MEF2A_6 | 107 | 116 | PF00069 | 0.361 |
| DOC_MAPK_MEF2A_6 | 124 | 132 | PF00069 | 0.361 |
| DOC_MAPK_MEF2A_6 | 75 | 84 | PF00069 | 0.423 |
| DOC_MAPK_NFAT4_5 | 75 | 83 | PF00069 | 0.440 |
| DOC_PP2B_LxvP_1 | 196 | 199 | PF13499 | 0.267 |
| DOC_USP7_MATH_1 | 304 | 308 | PF00917 | 0.618 |
| DOC_WW_Pin1_4 | 124 | 129 | PF00397 | 0.458 |
| DOC_WW_Pin1_4 | 246 | 251 | PF00397 | 0.415 |
| LIG_BH_BH3_1 | 105 | 121 | PF00452 | 0.378 |
| LIG_BRCT_BRCA1_1 | 196 | 200 | PF00533 | 0.267 |
| LIG_BRCT_BRCA1_1 | 288 | 292 | PF00533 | 0.381 |
| LIG_deltaCOP1_diTrp_1 | 148 | 154 | PF00928 | 0.215 |
| LIG_eIF4E_1 | 131 | 137 | PF01652 | 0.287 |
| LIG_FHA_1 | 125 | 131 | PF00498 | 0.470 |
| LIG_FHA_1 | 2 | 8 | PF00498 | 0.604 |
| LIG_FHA_1 | 226 | 232 | PF00498 | 0.282 |
| LIG_FHA_1 | 236 | 242 | PF00498 | 0.219 |
| LIG_FHA_1 | 250 | 256 | PF00498 | 0.464 |
| LIG_FHA_1 | 277 | 283 | PF00498 | 0.305 |
| LIG_FHA_1 | 95 | 101 | PF00498 | 0.251 |
| LIG_FHA_2 | 318 | 324 | PF00498 | 0.658 |
| LIG_LIR_Gen_1 | 133 | 142 | PF02991 | 0.308 |
| LIG_LIR_Gen_1 | 159 | 167 | PF02991 | 0.270 |
| LIG_LIR_Gen_1 | 16 | 27 | PF02991 | 0.400 |
| LIG_LIR_Gen_1 | 228 | 237 | PF02991 | 0.322 |
| LIG_LIR_Gen_1 | 238 | 247 | PF02991 | 0.264 |
| LIG_LIR_Gen_1 | 81 | 92 | PF02991 | 0.250 |
| LIG_LIR_Nem_3 | 152 | 157 | PF02991 | 0.257 |
| LIG_LIR_Nem_3 | 159 | 163 | PF02991 | 0.245 |
| LIG_LIR_Nem_3 | 16 | 22 | PF02991 | 0.400 |
| LIG_LIR_Nem_3 | 166 | 172 | PF02991 | 0.238 |
| LIG_LIR_Nem_3 | 197 | 203 | PF02991 | 0.344 |
| LIG_LIR_Nem_3 | 219 | 225 | PF02991 | 0.264 |
| LIG_LIR_Nem_3 | 228 | 232 | PF02991 | 0.286 |
| LIG_LIR_Nem_3 | 238 | 242 | PF02991 | 0.212 |
| LIG_LIR_Nem_3 | 279 | 284 | PF02991 | 0.324 |
| LIG_LIR_Nem_3 | 65 | 69 | PF02991 | 0.477 |
| LIG_NRBOX | 138 | 144 | PF00104 | 0.219 |
| LIG_Pex14_2 | 239 | 243 | PF04695 | 0.282 |
| LIG_SH2_CRK | 187 | 191 | PF00017 | 0.426 |
| LIG_SH2_CRK | 192 | 196 | PF00017 | 0.262 |
| LIG_SH2_STAP1 | 169 | 173 | PF00017 | 0.267 |
| LIG_SH2_STAP1 | 35 | 39 | PF00017 | 0.282 |
| LIG_SH2_STAT5 | 131 | 134 | PF00017 | 0.267 |
| LIG_SH2_STAT5 | 169 | 172 | PF00017 | 0.252 |
| LIG_SH2_STAT5 | 281 | 284 | PF00017 | 0.263 |
| LIG_SH2_STAT5 | 294 | 297 | PF00017 | 0.242 |
| LIG_SUMO_SIM_anti_2 | 323 | 329 | PF11976 | 0.545 |
| LIG_SUMO_SIM_par_1 | 112 | 118 | PF11976 | 0.280 |
| LIG_SUMO_SIM_par_1 | 284 | 289 | PF11976 | 0.400 |
| LIG_SUMO_SIM_par_1 | 42 | 48 | PF11976 | 0.342 |
| LIG_SUMO_SIM_par_1 | 9 | 16 | PF11976 | 0.435 |
| LIG_TYR_ITIM | 190 | 195 | PF00017 | 0.267 |
| LIG_TYR_ITSM | 277 | 284 | PF00017 | 0.287 |
| LIG_UBA3_1 | 113 | 119 | PF00899 | 0.368 |
| LIG_UBA3_1 | 138 | 146 | PF00899 | 0.219 |
| LIG_UBA3_1 | 88 | 93 | PF00899 | 0.280 |
| LIG_WRC_WIRS_1 | 131 | 136 | PF05994 | 0.312 |
| LIG_WRC_WIRS_1 | 157 | 162 | PF05994 | 0.285 |
| LIG_WRC_WIRS_1 | 226 | 231 | PF05994 | 0.295 |
| LIG_WRC_WIRS_1 | 236 | 241 | PF05994 | 0.222 |
| MOD_CK1_1 | 165 | 171 | PF00069 | 0.288 |
| MOD_CK1_1 | 18 | 24 | PF00069 | 0.284 |
| MOD_CK1_1 | 235 | 241 | PF00069 | 0.286 |
| MOD_CK1_1 | 246 | 252 | PF00069 | 0.426 |
| MOD_CK1_1 | 307 | 313 | PF00069 | 0.638 |
| MOD_CK1_1 | 334 | 340 | PF00069 | 0.665 |
| MOD_CK1_1 | 91 | 97 | PF00069 | 0.254 |
| MOD_CK2_1 | 3 | 9 | PF00069 | 0.475 |
| MOD_CK2_1 | 305 | 311 | PF00069 | 0.562 |
| MOD_CK2_1 | 317 | 323 | PF00069 | 0.586 |
| MOD_CK2_1 | 335 | 341 | PF00069 | 0.542 |
| MOD_GlcNHglycan | 212 | 215 | PF01048 | 0.531 |
| MOD_GlcNHglycan | 288 | 291 | PF01048 | 0.287 |
| MOD_GSK3_1 | 163 | 170 | PF00069 | 0.272 |
| MOD_GSK3_1 | 176 | 183 | PF00069 | 0.436 |
| MOD_GSK3_1 | 227 | 234 | PF00069 | 0.380 |
| MOD_GSK3_1 | 245 | 252 | PF00069 | 0.343 |
| MOD_GSK3_1 | 317 | 324 | PF00069 | 0.601 |
| MOD_GSK3_1 | 331 | 338 | PF00069 | 0.671 |
| MOD_GSK3_1 | 87 | 94 | PF00069 | 0.291 |
| MOD_N-GLC_1 | 1 | 6 | PF02516 | 0.377 |
| MOD_N-GLC_1 | 334 | 339 | PF02516 | 0.411 |
| MOD_NEK2_1 | 1 | 6 | PF00069 | 0.655 |
| MOD_NEK2_1 | 156 | 161 | PF00069 | 0.246 |
| MOD_NEK2_1 | 225 | 230 | PF00069 | 0.334 |
| MOD_NEK2_1 | 232 | 237 | PF00069 | 0.276 |
| MOD_NEK2_1 | 245 | 250 | PF00069 | 0.337 |
| MOD_NEK2_1 | 292 | 297 | PF00069 | 0.359 |
| MOD_NEK2_1 | 87 | 92 | PF00069 | 0.264 |
| MOD_Plk_4 | 101 | 107 | PF00069 | 0.262 |
| MOD_Plk_4 | 138 | 144 | PF00069 | 0.255 |
| MOD_Plk_4 | 167 | 173 | PF00069 | 0.250 |
| MOD_Plk_4 | 20 | 26 | PF00069 | 0.330 |
| MOD_Plk_4 | 216 | 222 | PF00069 | 0.203 |
| MOD_Plk_4 | 232 | 238 | PF00069 | 0.265 |
| MOD_Plk_4 | 251 | 257 | PF00069 | 0.380 |
| MOD_Plk_4 | 262 | 268 | PF00069 | 0.413 |
| MOD_Plk_4 | 321 | 327 | PF00069 | 0.547 |
| MOD_Plk_4 | 78 | 84 | PF00069 | 0.252 |
| MOD_ProDKin_1 | 124 | 130 | PF00069 | 0.458 |
| MOD_ProDKin_1 | 246 | 252 | PF00069 | 0.415 |
| TRG_DiLeu_BaEn_1 | 323 | 328 | PF01217 | 0.550 |
| TRG_ENDOCYTIC_2 | 131 | 134 | PF00928 | 0.267 |
| TRG_ENDOCYTIC_2 | 187 | 190 | PF00928 | 0.426 |
| TRG_ENDOCYTIC_2 | 192 | 195 | PF00928 | 0.262 |
| TRG_ENDOCYTIC_2 | 281 | 284 | PF00928 | 0.273 |
| TRG_ENDOCYTIC_2 | 294 | 297 | PF00928 | 0.308 |
| TRG_ENDOCYTIC_2 | 66 | 69 | PF00928 | 0.415 |
| TRG_NES_CRM1_1 | 103 | 118 | PF08389 | 0.268 |
| TRG_NES_CRM1_1 | 36 | 47 | PF08389 | 0.270 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1HVS9 | Leptomonas seymouri | 67% | 100% |
| A0A0S4IKV6 | Bodo saltans | 21% | 97% |
| A0A0S4J6I5 | Bodo saltans | 25% | 100% |
| A0A0S4JCA2 | Bodo saltans | 24% | 100% |
| A0A0S4JRM6 | Bodo saltans | 48% | 100% |
| A0A1X0NIJ8 | Trypanosomatidae | 23% | 100% |
| A0A1X0NJJ3 | Trypanosomatidae | 22% | 100% |
| A0A1X0P5Z4 | Trypanosomatidae | 24% | 100% |
| A0A1X0P9U5 | Trypanosomatidae | 55% | 100% |
| A0A3Q8IUT2 | Leishmania donovani | 99% | 100% |
| A0A422N243 | Trypanosoma rangeli | 54% | 100% |
| A1C9R4 | Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) | 32% | 90% |
| A1CZJ3 | Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) | 31% | 89% |
| A1DA52 | Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) | 31% | 96% |
| A2AKQ0 | Mus musculus | 23% | 96% |
| A2R9P4 | Aspergillus niger (strain CBS 513.88 / FGSC A1513) | 30% | 90% |
| A2VE55 | Bos taurus | 22% | 96% |
| A3LWX1 | Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) | 30% | 100% |
| A4HB31 | Leishmania braziliensis | 79% | 100% |
| A4RM13 | Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) | 29% | 87% |
| A5DIN8 | Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) | 29% | 97% |
| A6RJQ8 | Botryotinia fuckeliana (strain B05.10) | 29% | 87% |
| A6ZTW6 | Saccharomyces cerevisiae (strain YJM789) | 28% | 100% |
| A7E558 | Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) | 29% | 87% |
| A7S1L6 | Nematostella vectensis | 22% | 100% |
| A7TES5 | Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) | 27% | 100% |
| A7TR80 | Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) | 28% | 100% |
| A8MRY9 | Arabidopsis thaliana | 24% | 99% |
| A8N9T6 | Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) | 28% | 95% |
| A9UUB8 | Monosiga brevicollis | 23% | 100% |
| B0DI84 | Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) | 27% | 100% |
| B0Y384 | Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) | 31% | 89% |
| B3LHR7 | Saccharomyces cerevisiae (strain RM11-1a) | 28% | 100% |
| B3LS51 | Saccharomyces cerevisiae (strain RM11-1a) | 30% | 100% |
| B5VHH5 | Saccharomyces cerevisiae (strain AWRI1631) | 30% | 100% |
| C7GSI5 | Saccharomyces cerevisiae (strain JAY291) | 30% | 100% |
| C7GUZ7 | Saccharomyces cerevisiae (strain JAY291) | 28% | 100% |
| C8Z742 | Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) | 28% | 100% |
| C8Z830 | Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) | 28% | 100% |
| C9ZM22 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 44% | 100% |
| E9B5A1 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 95% | 100% |
| P0CE11 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 30% | 100% |
| P0CS02 | Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) | 28% | 86% |
| P0CS03 | Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) | 28% | 86% |
| P0CS04 | Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) | 28% | 81% |
| P0CS05 | Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) | 28% | 81% |
| P40107 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 28% | 100% |
| Q0CA27 | Aspergillus terreus (strain NIH 2624 / FGSC A1156) | 30% | 89% |
| Q0UG89 | Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) | 31% | 90% |
| Q15B89 | Sus scrofa | 24% | 99% |
| Q18779 | Caenorhabditis elegans | 24% | 100% |
| Q1DTI4 | Coccidioides immitis (strain RS) | 30% | 88% |
| Q2AAF6 | Komagataella pastoris | 30% | 100% |
| Q2HA88 | Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) | 29% | 87% |
| Q2UTL1 | Aspergillus oryzae (strain ATCC 42149 / RIB 40) | 32% | 90% |
| Q4WTQ6 | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) | 31% | 89% |
| Q54YK1 | Dictyostelium discoideum | 26% | 89% |
| Q5A477 | Candida albicans (strain SC5314 / ATCC MYA-2876) | 30% | 92% |
| Q5AQY2 | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) | 31% | 96% |
| Q5AS82 | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) | 32% | 90% |
| Q5RDC9 | Pongo abelii | 23% | 96% |
| Q6C0U0 | Yarrowia lipolytica (strain CLIB 122 / E 150) | 32% | 100% |
| Q6CYD0 | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) | 28% | 100% |
| Q6FRE5 | Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) | 30% | 100% |
| Q753T9 | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) | 28% | 100% |
| Q762D5 | Mus musculus | 24% | 100% |
| Q76EJ3 | Homo sapiens | 24% | 100% |
| Q7SBC5 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 28% | 87% |
| Q84L08 | Arabidopsis thaliana | 25% | 100% |
| Q84L09 | Arabidopsis thaliana | 30% | 91% |
| Q941R4 | Arabidopsis thaliana | 28% | 100% |
| Q94B65 | Arabidopsis thaliana | 25% | 100% |
| Q95YI5 | Drosophila melanogaster | 25% | 91% |
| Q968A5 | Caenorhabditis elegans | 23% | 94% |
| Q9BIR6 | Leishmania major | 94% | 100% |
| Q9NTN3 | Homo sapiens | 23% | 96% |
| Q9S845 | Arabidopsis thaliana | 23% | 92% |
| Q9UTK8 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 31% | 99% |
| V5BJU5 | Trypanosoma cruzi | 21% | 88% |
| V5BMJ0 | Trypanosoma cruzi | 24% | 100% |
| V5DLW9 | Trypanosoma cruzi | 56% | 95% |