LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IA83_LEIIN
TriTrypDb:
LINF_340037350
Length:
636

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 23
NetGPI no yes: 0, no: 23
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 21
GO:0110165 cellular anatomical entity 1 21
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Expansion

Sequence features

A4IA83
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IA83

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 56 60 PF00656 0.778
CLV_NRD_NRD_1 175 177 PF00675 0.402
CLV_NRD_NRD_1 342 344 PF00675 0.324
CLV_NRD_NRD_1 406 408 PF00675 0.385
CLV_PCSK_KEX2_1 175 177 PF00082 0.371
CLV_PCSK_KEX2_1 342 344 PF00082 0.326
CLV_PCSK_KEX2_1 396 398 PF00082 0.403
CLV_PCSK_KEX2_1 406 408 PF00082 0.380
CLV_PCSK_KEX2_1 574 576 PF00082 0.477
CLV_PCSK_PC1ET2_1 396 398 PF00082 0.415
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P2M1 Leptomonas seymouri 31% 100%
A0A0N1HRT9 Leptomonas seymouri 31% 100%
A0A0N1P9A0 Leptomonas seymouri 30% 100%
A0A0N1PBU6 Leptomonas seymouri 54% 100%
A0A1X0P9W4 Trypanosomatidae 37% 100%
A0A3Q8IFF3 Leishmania donovani 31% 98%
A0A3Q8ISH4 Leishmania donovani 33% 100%
A0A3R7KFP4 Trypanosoma rangeli 36% 100%
A0A3S7X483 Leishmania donovani 31% 98%
A0A3S7X888 Leishmania donovani 99% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS