LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IA45_LEIIN
TriTrypDb:
LINF_340032900
Length:
572

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IA45
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IA45

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 472 476 PF00656 0.637
CLV_NRD_NRD_1 119 121 PF00675 0.499
CLV_NRD_NRD_1 447 449 PF00675 0.487
CLV_NRD_NRD_1 92 94 PF00675 0.595
CLV_PCSK_FUR_1 324 328 PF00082 0.520
CLV_PCSK_FUR_1 330 334 PF00082 0.559
CLV_PCSK_KEX2_1 119 121 PF00082 0.542
CLV_PCSK_KEX2_1 326 328 PF00082 0.538
CLV_PCSK_KEX2_1 329 331 PF00082 0.574
CLV_PCSK_KEX2_1 332 334 PF00082 0.588
CLV_PCSK_KEX2_1 447 449 PF00082 0.502
CLV_PCSK_KEX2_1 92 94 PF00082 0.595
CLV_PCSK_PC1ET2_1 326 328 PF00082 0.591
CLV_PCSK_PC1ET2_1 329 331 PF00082 0.604
CLV_PCSK_PC1ET2_1 332 334 PF00082 0.587
CLV_PCSK_PC7_1 322 328 PF00082 0.517
CLV_PCSK_PC7_1 443 449 PF00082 0.493
CLV_PCSK_SKI1_1 431 435 PF00082 0.585
DEG_APCC_DBOX_1 442 450 PF00400 0.462
DEG_SCF_FBW7_1 65 72 PF00400 0.535
DEG_SPOP_SBC_1 283 287 PF00917 0.559
DOC_CKS1_1 66 71 PF01111 0.506
DOC_CYCLIN_yCln2_LP_2 146 152 PF00134 0.638
DOC_PP2B_LxvP_1 146 149 PF13499 0.584
DOC_PP4_FxxP_1 53 56 PF00568 0.675
DOC_USP7_MATH_1 159 163 PF00917 0.632
DOC_USP7_MATH_1 167 171 PF00917 0.660
DOC_USP7_MATH_1 183 187 PF00917 0.775
DOC_USP7_MATH_1 281 285 PF00917 0.705
DOC_USP7_MATH_1 348 352 PF00917 0.703
DOC_USP7_MATH_1 353 357 PF00917 0.801
DOC_USP7_MATH_1 388 392 PF00917 0.674
DOC_USP7_MATH_1 395 399 PF00917 0.642
DOC_USP7_MATH_1 413 417 PF00917 0.527
DOC_USP7_MATH_1 482 486 PF00917 0.672
DOC_WW_Pin1_4 102 107 PF00397 0.635
DOC_WW_Pin1_4 223 228 PF00397 0.725
DOC_WW_Pin1_4 243 248 PF00397 0.574
DOC_WW_Pin1_4 257 262 PF00397 0.596
DOC_WW_Pin1_4 270 275 PF00397 0.616
DOC_WW_Pin1_4 335 340 PF00397 0.562
DOC_WW_Pin1_4 408 413 PF00397 0.653
DOC_WW_Pin1_4 421 426 PF00397 0.608
DOC_WW_Pin1_4 556 561 PF00397 0.608
DOC_WW_Pin1_4 61 66 PF00397 0.585
DOC_WW_Pin1_4 79 84 PF00397 0.482
LIG_14-3-3_CanoR_1 169 177 PF00244 0.786
LIG_14-3-3_CanoR_1 182 188 PF00244 0.577
LIG_14-3-3_CanoR_1 39 45 PF00244 0.517
LIG_14-3-3_CanoR_1 390 399 PF00244 0.557
LIG_14-3-3_CanoR_1 420 428 PF00244 0.612
LIG_CaM_IQ_9 314 329 PF13499 0.524
LIG_EVH1_1 498 502 PF00568 0.535
LIG_FHA_1 107 113 PF00498 0.622
LIG_FHA_1 134 140 PF00498 0.501
LIG_FHA_1 182 188 PF00498 0.635
LIG_FHA_1 285 291 PF00498 0.751
LIG_FHA_1 422 428 PF00498 0.651
LIG_FHA_2 152 158 PF00498 0.668
LIG_FHA_2 169 175 PF00498 0.598
LIG_FHA_2 470 476 PF00498 0.676
LIG_LIR_Apic_2 245 251 PF02991 0.630
LIG_LIR_Apic_2 63 69 PF02991 0.532
LIG_LIR_Gen_1 299 308 PF02991 0.433
LIG_LIR_Gen_1 364 373 PF02991 0.576
LIG_LIR_Gen_1 450 461 PF02991 0.553
LIG_LIR_Gen_1 532 539 PF02991 0.545
LIG_LIR_Gen_1 544 554 PF02991 0.580
LIG_LIR_Gen_1 68 78 PF02991 0.490
LIG_LIR_Nem_3 294 300 PF02991 0.481
LIG_LIR_Nem_3 364 369 PF02991 0.565
LIG_LIR_Nem_3 450 456 PF02991 0.533
LIG_LIR_Nem_3 532 537 PF02991 0.545
LIG_LIR_Nem_3 68 74 PF02991 0.493
LIG_Pex14_1 297 301 PF04695 0.438
LIG_Pex14_1 304 308 PF04695 0.417
LIG_SH2_CRK 115 119 PF00017 0.535
LIG_SH2_CRK 308 312 PF00017 0.428
LIG_SH2_CRK 453 457 PF00017 0.546
LIG_SH2_CRK 66 70 PF00017 0.575
LIG_SH2_SRC 366 369 PF00017 0.581
LIG_SH2_STAP1 298 302 PF00017 0.477
LIG_SH2_STAP1 312 316 PF00017 0.450
LIG_SH2_STAP1 366 370 PF00017 0.557
LIG_SH2_STAT3 307 310 PF00017 0.427
LIG_SH2_STAT3 312 315 PF00017 0.446
LIG_SH3_1 493 499 PF00018 0.577
LIG_SH3_2 409 414 PF14604 0.664
LIG_SH3_3 258 264 PF00018 0.662
LIG_SH3_3 287 293 PF00018 0.567
LIG_SH3_3 406 412 PF00018 0.698
LIG_SH3_3 422 428 PF00018 0.549
LIG_SH3_3 493 499 PF00018 0.674
LIG_SH3_3 78 84 PF00018 0.467
LIG_TRAF2_1 171 174 PF00917 0.573
LIG_TRAF2_1 316 319 PF00917 0.420
LIG_TYR_ITSM 362 369 PF00017 0.583
LIG_WW_3 262 266 PF00397 0.647
MOD_CDC14_SPxK_1 411 414 PF00782 0.685
MOD_CDC14_SPxK_1 64 67 PF00782 0.548
MOD_CDK_SPK_2 421 426 PF00069 0.692
MOD_CDK_SPxK_1 408 414 PF00069 0.686
MOD_CDK_SPxK_1 61 67 PF00069 0.582
MOD_CDK_SPxxK_3 335 342 PF00069 0.570
MOD_CK1_1 105 111 PF00069 0.699
MOD_CK1_1 125 131 PF00069 0.541
MOD_CK1_1 186 192 PF00069 0.789
MOD_CK1_1 284 290 PF00069 0.669
MOD_CK1_1 335 341 PF00069 0.621
MOD_CK1_1 393 399 PF00069 0.806
MOD_CK1_1 416 422 PF00069 0.627
MOD_CK2_1 151 157 PF00069 0.564
MOD_CK2_1 167 173 PF00069 0.595
MOD_CK2_1 348 354 PF00069 0.809
MOD_CK2_1 388 394 PF00069 0.561
MOD_CK2_1 94 100 PF00069 0.628
MOD_Cter_Amidation 327 330 PF01082 0.594
MOD_DYRK1A_RPxSP_1 223 227 PF00069 0.632
MOD_GlcNHglycan 161 164 PF01048 0.667
MOD_GlcNHglycan 189 192 PF01048 0.730
MOD_GlcNHglycan 233 236 PF01048 0.687
MOD_GlcNHglycan 257 260 PF01048 0.653
MOD_GlcNHglycan 350 353 PF01048 0.682
MOD_GlcNHglycan 399 402 PF01048 0.642
MOD_GlcNHglycan 484 487 PF01048 0.692
MOD_GlcNHglycan 526 529 PF01048 0.795
MOD_GlcNHglycan 9 12 PF01048 0.548
MOD_GSK3_1 100 107 PF00069 0.632
MOD_GSK3_1 182 189 PF00069 0.781
MOD_GSK3_1 219 226 PF00069 0.628
MOD_GSK3_1 237 244 PF00069 0.532
MOD_GSK3_1 266 273 PF00069 0.745
MOD_GSK3_1 343 350 PF00069 0.641
MOD_GSK3_1 393 400 PF00069 0.662
MOD_GSK3_1 452 459 PF00069 0.473
MOD_GSK3_1 520 527 PF00069 0.700
MOD_GSK3_1 552 559 PF00069 0.787
MOD_GSK3_1 61 68 PF00069 0.695
MOD_N-GLC_1 542 547 PF02516 0.572
MOD_NEK2_1 17 22 PF00069 0.566
MOD_NEK2_1 242 247 PF00069 0.624
MOD_NEK2_1 456 461 PF00069 0.585
MOD_NEK2_1 94 99 PF00069 0.556
MOD_NEK2_2 237 242 PF00069 0.531
MOD_PIKK_1 122 128 PF00454 0.497
MOD_PIKK_1 419 425 PF00454 0.635
MOD_PKA_1 332 338 PF00069 0.639
MOD_PKA_2 159 165 PF00069 0.654
MOD_PKA_2 168 174 PF00069 0.597
MOD_PKA_2 181 187 PF00069 0.572
MOD_PKA_2 332 338 PF00069 0.639
MOD_PKA_2 419 425 PF00069 0.624
MOD_PKA_2 524 530 PF00069 0.627
MOD_PKA_2 552 558 PF00069 0.720
MOD_PKB_1 180 188 PF00069 0.633
MOD_PKB_1 540 548 PF00069 0.530
MOD_Plk_1 353 359 PF00069 0.768
MOD_Plk_1 393 399 PF00069 0.598
MOD_Plk_1 542 548 PF00069 0.635
MOD_Plk_2-3 168 174 PF00069 0.625
MOD_ProDKin_1 102 108 PF00069 0.632
MOD_ProDKin_1 223 229 PF00069 0.723
MOD_ProDKin_1 243 249 PF00069 0.573
MOD_ProDKin_1 257 263 PF00069 0.596
MOD_ProDKin_1 270 276 PF00069 0.615
MOD_ProDKin_1 335 341 PF00069 0.566
MOD_ProDKin_1 408 414 PF00069 0.655
MOD_ProDKin_1 421 427 PF00069 0.606
MOD_ProDKin_1 556 562 PF00069 0.610
MOD_ProDKin_1 61 67 PF00069 0.575
MOD_ProDKin_1 79 85 PF00069 0.487
TRG_DiLeu_BaEn_4 173 179 PF01217 0.577
TRG_DiLeu_BaEn_4 451 457 PF01217 0.517
TRG_ENDOCYTIC_2 115 118 PF00928 0.528
TRG_ENDOCYTIC_2 302 305 PF00928 0.440
TRG_ENDOCYTIC_2 308 311 PF00928 0.425
TRG_ENDOCYTIC_2 366 369 PF00928 0.567
TRG_ENDOCYTIC_2 453 456 PF00928 0.544
TRG_ER_diArg_1 118 120 PF00400 0.498
TRG_ER_diArg_1 446 448 PF00400 0.661
TRG_ER_diArg_1 565 568 PF00400 0.692
TRG_ER_diArg_1 91 93 PF00400 0.583
TRG_NLS_MonoExtC_3 325 330 PF00514 0.507
TRG_NLS_MonoExtN_4 324 330 PF00514 0.506
TRG_Pf-PMV_PEXEL_1 119 123 PF00026 0.522
TRG_Pf-PMV_PEXEL_1 223 228 PF00026 0.603
TRG_Pf-PMV_PEXEL_1 447 451 PF00026 0.530

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P607 Leptomonas seymouri 28% 100%
A0A3Q8IEH1 Leishmania donovani 99% 100%
A4HAY6 Leishmania braziliensis 57% 97%
E9B559 Leishmania mexicana (strain MHOM/GT/2001/U1103) 80% 100%
Q4Q2S6 Leishmania major 86% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS