LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IA32_LEIIN
TriTrypDb:
LINF_340031500 * , LINF_340031600 *
Length:
1342

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 2
NetGPI no yes: 0, no: 2
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IA32
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IA32

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1003 1007 PF00656 0.519
CLV_C14_Caspase3-7 1012 1016 PF00656 0.425
CLV_C14_Caspase3-7 1119 1123 PF00656 0.501
CLV_C14_Caspase3-7 1128 1132 PF00656 0.411
CLV_C14_Caspase3-7 1305 1309 PF00656 0.435
CLV_C14_Caspase3-7 156 160 PF00656 0.552
CLV_C14_Caspase3-7 267 271 PF00656 0.646
CLV_C14_Caspase3-7 539 543 PF00656 0.484
CLV_C14_Caspase3-7 548 552 PF00656 0.448
CLV_C14_Caspase3-7 655 659 PF00656 0.511
CLV_C14_Caspase3-7 664 668 PF00656 0.410
CLV_C14_Caspase3-7 771 775 PF00656 0.525
CLV_C14_Caspase3-7 780 784 PF00656 0.429
CLV_C14_Caspase3-7 887 891 PF00656 0.519
CLV_C14_Caspase3-7 896 900 PF00656 0.420
CLV_NRD_NRD_1 1223 1225 PF00675 0.414
CLV_NRD_NRD_1 1237 1239 PF00675 0.321
CLV_NRD_NRD_1 151 153 PF00675 0.772
CLV_NRD_NRD_1 279 281 PF00675 0.392
CLV_NRD_NRD_1 337 339 PF00675 0.493
CLV_NRD_NRD_1 343 345 PF00675 0.453
CLV_NRD_NRD_1 379 381 PF00675 0.691
CLV_PCSK_KEX2_1 1223 1225 PF00082 0.414
CLV_PCSK_KEX2_1 1236 1238 PF00082 0.344
CLV_PCSK_KEX2_1 151 153 PF00082 0.682
CLV_PCSK_KEX2_1 278 280 PF00082 0.411
CLV_PCSK_KEX2_1 337 339 PF00082 0.493
CLV_PCSK_KEX2_1 343 345 PF00082 0.453
CLV_PCSK_KEX2_1 379 381 PF00082 0.691
CLV_PCSK_SKI1_1 1014 1018 PF00082 0.436
CLV_PCSK_SKI1_1 1130 1134 PF00082 0.422
CLV_PCSK_SKI1_1 1169 1173 PF00082 0.427
CLV_PCSK_SKI1_1 1304 1308 PF00082 0.485
CLV_PCSK_SKI1_1 152 156 PF00082 0.653
CLV_PCSK_SKI1_1 164 168 PF00082 0.696
CLV_PCSK_SKI1_1 229 233 PF00082 0.366
CLV_PCSK_SKI1_1 273 277 PF00082 0.387
CLV_PCSK_SKI1_1 550 554 PF00082 0.426
CLV_PCSK_SKI1_1 666 670 PF00082 0.675
CLV_PCSK_SKI1_1 782 786 PF00082 0.444
CLV_PCSK_SKI1_1 898 902 PF00082 0.440
CLV_Separin_Metazoa 1205 1209 PF03568 0.444
DEG_APCC_DBOX_1 1309 1317 PF00400 0.480
DEG_APCC_KENBOX_2 91 95 PF00400 0.532
DEG_COP1_1 25 36 PF00400 0.512
DEG_SCF_FBW7_1 74 81 PF00400 0.568
DOC_CKS1_1 130 135 PF01111 0.576
DOC_CKS1_1 297 302 PF01111 0.461
DOC_CKS1_1 501 506 PF01111 0.536
DOC_CKS1_1 83 88 PF01111 0.564
DOC_CYCLIN_yCln2_LP_2 501 507 PF00134 0.537
DOC_MAPK_MEF2A_6 1182 1189 PF00069 0.453
DOC_MAPK_MEF2A_6 256 263 PF00069 0.306
DOC_MAPK_MEF2A_6 66 74 PF00069 0.564
DOC_MAPK_MEF2A_6 8 17 PF00069 0.567
DOC_PP1_RVXF_1 271 278 PF00149 0.347
DOC_PP4_MxPP_1 301 304 PF00568 0.521
DOC_USP7_MATH_1 1044 1048 PF00917 0.373
DOC_USP7_MATH_1 1108 1112 PF00917 0.392
DOC_USP7_MATH_1 112 116 PF00917 0.561
DOC_USP7_MATH_1 1160 1164 PF00917 0.399
DOC_USP7_MATH_1 1240 1244 PF00917 0.385
DOC_USP7_MATH_1 528 532 PF00917 0.477
DOC_USP7_MATH_1 580 584 PF00917 0.478
DOC_USP7_MATH_1 644 648 PF00917 0.408
DOC_USP7_MATH_1 696 700 PF00917 0.375
DOC_USP7_MATH_1 760 764 PF00917 0.456
DOC_USP7_MATH_1 78 82 PF00917 0.573
DOC_USP7_MATH_1 812 816 PF00917 0.385
DOC_USP7_MATH_1 876 880 PF00917 0.410
DOC_USP7_MATH_1 928 932 PF00917 0.392
DOC_USP7_MATH_1 95 99 PF00917 0.516
DOC_USP7_MATH_1 992 996 PF00917 0.412
DOC_WW_Pin1_4 108 113 PF00397 0.547
DOC_WW_Pin1_4 1181 1186 PF00397 0.490
DOC_WW_Pin1_4 129 134 PF00397 0.577
DOC_WW_Pin1_4 2 7 PF00397 0.547
DOC_WW_Pin1_4 296 301 PF00397 0.447
DOC_WW_Pin1_4 35 40 PF00397 0.503
DOC_WW_Pin1_4 486 491 PF00397 0.589
DOC_WW_Pin1_4 500 505 PF00397 0.673
DOC_WW_Pin1_4 74 79 PF00397 0.568
DOC_WW_Pin1_4 82 87 PF00397 0.552
LIG_14-3-3_CanoR_1 121 129 PF00244 0.572
LIG_14-3-3_CanoR_1 1223 1232 PF00244 0.342
LIG_14-3-3_CanoR_1 1336 1341 PF00244 0.464
LIG_14-3-3_CanoR_1 151 155 PF00244 0.566
LIG_14-3-3_CanoR_1 174 179 PF00244 0.778
LIG_14-3-3_CanoR_1 291 297 PF00244 0.356
LIG_14-3-3_CanoR_1 337 346 PF00244 0.474
LIG_BIR_III_4 1015 1019 PF00653 0.372
LIG_BIR_III_4 1131 1135 PF00653 0.360
LIG_BIR_III_4 551 555 PF00653 0.362
LIG_BIR_III_4 667 671 PF00653 0.363
LIG_BIR_III_4 783 787 PF00653 0.378
LIG_BIR_III_4 899 903 PF00653 0.378
LIG_CaM_IQ_9 1313 1328 PF13499 0.467
LIG_FHA_1 1100 1106 PF00498 0.410
LIG_FHA_1 1115 1121 PF00498 0.423
LIG_FHA_1 122 128 PF00498 0.800
LIG_FHA_1 1220 1226 PF00498 0.360
LIG_FHA_1 130 136 PF00498 0.713
LIG_FHA_1 230 236 PF00498 0.330
LIG_FHA_1 241 247 PF00498 0.343
LIG_FHA_1 393 399 PF00498 0.450
LIG_FHA_1 410 416 PF00498 0.448
LIG_FHA_1 496 502 PF00498 0.489
LIG_FHA_1 520 526 PF00498 0.422
LIG_FHA_1 535 541 PF00498 0.410
LIG_FHA_1 636 642 PF00498 0.419
LIG_FHA_1 651 657 PF00498 0.437
LIG_FHA_1 74 80 PF00498 0.520
LIG_FHA_1 752 758 PF00498 0.434
LIG_FHA_1 767 773 PF00498 0.450
LIG_FHA_1 83 89 PF00498 0.549
LIG_FHA_1 868 874 PF00498 0.447
LIG_FHA_1 883 889 PF00498 0.447
LIG_FHA_1 97 103 PF00498 0.528
LIG_FHA_1 984 990 PF00498 0.435
LIG_FHA_1 999 1005 PF00498 0.440
LIG_FHA_2 121 127 PF00498 0.574
LIG_FHA_2 23 29 PF00498 0.525
LIG_FHA_2 265 271 PF00498 0.632
LIG_FHA_2 350 356 PF00498 0.452
LIG_FHA_2 427 433 PF00498 0.427
LIG_FHA_2 57 63 PF00498 0.535
LIG_HCF-1_HBM_1 1292 1295 PF13415 0.459
LIG_LIR_Apic_2 34 39 PF02991 0.555
LIG_LIR_Gen_1 1292 1302 PF02991 0.489
LIG_LIR_Gen_1 214 224 PF02991 0.469
LIG_LIR_Gen_1 290 301 PF02991 0.653
LIG_LIR_Gen_1 445 454 PF02991 0.459
LIG_LIR_Nem_3 1292 1298 PF02991 0.499
LIG_LIR_Nem_3 214 219 PF02991 0.553
LIG_LIR_Nem_3 290 296 PF02991 0.611
LIG_LIR_Nem_3 445 449 PF02991 0.465
LIG_PCNA_TLS_4 1272 1279 PF02747 0.390
LIG_RPA_C_Fungi 1224 1236 PF08784 0.366
LIG_SH2_CRK 36 40 PF00017 0.558
LIG_SH2_CRK 446 450 PF00017 0.385
LIG_SH2_SRC 1278 1281 PF00017 0.406
LIG_SH2_STAP1 1295 1299 PF00017 0.458
LIG_SH2_STAP1 460 464 PF00017 0.370
LIG_SH2_STAT3 1113 1116 PF00017 0.455
LIG_SH2_STAT3 460 463 PF00017 0.418
LIG_SH2_STAT3 533 536 PF00017 0.469
LIG_SH2_STAT3 649 652 PF00017 0.469
LIG_SH2_STAT3 765 768 PF00017 0.479
LIG_SH2_STAT3 881 884 PF00017 0.480
LIG_SH2_STAT3 997 1000 PF00017 0.468
LIG_SH2_STAT5 1278 1281 PF00017 0.406
LIG_SH2_STAT5 36 39 PF00017 0.559
LIG_SH2_STAT5 446 449 PF00017 0.497
LIG_SH2_STAT5 521 524 PF00017 0.427
LIG_SH3_3 14 20 PF00018 0.548
LIG_SH3_3 167 173 PF00018 0.544
LIG_SH3_3 294 300 PF00018 0.406
LIG_SH3_3 83 89 PF00018 0.556
LIG_SUMO_SIM_anti_2 182 188 PF11976 0.547
LIG_SUMO_SIM_par_1 231 238 PF11976 0.363
LIG_SUMO_SIM_par_1 516 522 PF11976 0.453
LIG_TRAF2_1 1058 1061 PF00917 0.426
LIG_TRAF2_1 1093 1096 PF00917 0.420
LIG_TRAF2_1 42 45 PF00917 0.549
LIG_TRAF2_1 442 445 PF00917 0.455
LIG_TRAF2_1 594 597 PF00917 0.430
LIG_TRAF2_1 629 632 PF00917 0.433
LIG_TRAF2_1 710 713 PF00917 0.426
LIG_TRAF2_1 745 748 PF00917 0.429
LIG_TRAF2_1 826 829 PF00917 0.432
LIG_TRAF2_1 861 864 PF00917 0.448
LIG_TRAF2_1 942 945 PF00917 0.437
LIG_TRAF2_1 977 980 PF00917 0.440
LIG_UBA3_1 1298 1307 PF00899 0.485
LIG_WRC_WIRS_1 293 298 PF05994 0.372
LIG_WW_3 313 317 PF00397 0.547
MOD_CDC14_SPxK_1 5 8 PF00782 0.553
MOD_CDK_SPK_2 108 113 PF00069 0.580
MOD_CDK_SPK_2 82 87 PF00069 0.582
MOD_CDK_SPxK_1 2 8 PF00069 0.550
MOD_CDK_SPxxK_3 1181 1188 PF00069 0.456
MOD_CK1_1 1042 1048 PF00069 0.421
MOD_CK1_1 115 121 PF00069 0.525
MOD_CK1_1 1158 1164 PF00069 0.447
MOD_CK1_1 1244 1250 PF00069 0.358
MOD_CK1_1 1300 1306 PF00069 0.431
MOD_CK1_1 1334 1340 PF00069 0.507
MOD_CK1_1 193 199 PF00069 0.631
MOD_CK1_1 247 253 PF00069 0.457
MOD_CK1_1 31 37 PF00069 0.549
MOD_CK1_1 409 415 PF00069 0.376
MOD_CK1_1 519 525 PF00069 0.644
MOD_CK1_1 578 584 PF00069 0.637
MOD_CK1_1 694 700 PF00069 0.460
MOD_CK1_1 73 79 PF00069 0.567
MOD_CK1_1 810 816 PF00069 0.431
MOD_CK1_1 926 932 PF00069 0.441
MOD_CK1_1 98 104 PF00069 0.576
MOD_CK2_1 1042 1048 PF00069 0.421
MOD_CK2_1 1108 1114 PF00069 0.429
MOD_CK2_1 1158 1164 PF00069 0.447
MOD_CK2_1 120 126 PF00069 0.578
MOD_CK2_1 174 180 PF00069 0.654
MOD_CK2_1 22 28 PF00069 0.526
MOD_CK2_1 345 351 PF00069 0.437
MOD_CK2_1 370 376 PF00069 0.671
MOD_CK2_1 426 432 PF00069 0.425
MOD_CK2_1 463 469 PF00069 0.569
MOD_CK2_1 528 534 PF00069 0.458
MOD_CK2_1 56 62 PF00069 0.534
MOD_CK2_1 578 584 PF00069 0.430
MOD_CK2_1 644 650 PF00069 0.445
MOD_CK2_1 694 700 PF00069 0.422
MOD_CK2_1 760 766 PF00069 0.456
MOD_CK2_1 810 816 PF00069 0.431
MOD_CK2_1 876 882 PF00069 0.450
MOD_CK2_1 926 932 PF00069 0.441
MOD_CK2_1 992 998 PF00069 0.448
MOD_GlcNHglycan 1006 1009 PF01048 0.501
MOD_GlcNHglycan 1041 1044 PF01048 0.417
MOD_GlcNHglycan 1122 1125 PF01048 0.496
MOD_GlcNHglycan 1157 1160 PF01048 0.441
MOD_GlcNHglycan 1226 1229 PF01048 0.358
MOD_GlcNHglycan 1260 1263 PF01048 0.334
MOD_GlcNHglycan 1299 1302 PF01048 0.433
MOD_GlcNHglycan 144 147 PF01048 0.565
MOD_GlcNHglycan 187 190 PF01048 0.545
MOD_GlcNHglycan 19 23 PF01048 0.573
MOD_GlcNHglycan 33 36 PF01048 0.495
MOD_GlcNHglycan 381 384 PF01048 0.601
MOD_GlcNHglycan 542 545 PF01048 0.470
MOD_GlcNHglycan 577 580 PF01048 0.567
MOD_GlcNHglycan 658 661 PF01048 0.492
MOD_GlcNHglycan 693 696 PF01048 0.418
MOD_GlcNHglycan 774 777 PF01048 0.499
MOD_GlcNHglycan 809 812 PF01048 0.427
MOD_GlcNHglycan 890 893 PF01048 0.497
MOD_GlcNHglycan 925 928 PF01048 0.435
MOD_GSK3_1 108 115 PF00069 0.581
MOD_GSK3_1 1240 1247 PF00069 0.341
MOD_GSK3_1 1331 1338 PF00069 0.480
MOD_GSK3_1 138 145 PF00069 0.570
MOD_GSK3_1 18 25 PF00069 0.534
MOD_GSK3_1 203 210 PF00069 0.432
MOD_GSK3_1 229 236 PF00069 0.594
MOD_GSK3_1 240 247 PF00069 0.465
MOD_GSK3_1 27 34 PF00069 0.486
MOD_GSK3_1 292 299 PF00069 0.624
MOD_GSK3_1 345 352 PF00069 0.435
MOD_GSK3_1 388 395 PF00069 0.386
MOD_GSK3_1 7 14 PF00069 0.562
MOD_GSK3_1 70 77 PF00069 0.566
MOD_GSK3_1 78 85 PF00069 0.546
MOD_NEK2_1 120 125 PF00069 0.578
MOD_NEK2_1 165 170 PF00069 0.533
MOD_NEK2_1 292 297 PF00069 0.604
MOD_NEK2_1 56 61 PF00069 0.534
MOD_NEK2_1 70 75 PF00069 0.513
MOD_PIKK_1 112 118 PF00454 0.583
MOD_PIKK_1 1244 1250 PF00454 0.358
MOD_PIKK_1 370 376 PF00454 0.431
MOD_PIKK_1 388 394 PF00454 0.361
MOD_PIKK_1 414 420 PF00454 0.567
MOD_PIKK_1 436 442 PF00454 0.475
MOD_PIKK_1 495 501 PF00454 0.483
MOD_PKA_1 337 343 PF00069 0.435
MOD_PKA_1 379 385 PF00069 0.691
MOD_PKA_2 1099 1105 PF00069 0.359
MOD_PKA_2 112 118 PF00069 0.583
MOD_PKA_2 120 126 PF00069 0.547
MOD_PKA_2 1335 1341 PF00069 0.463
MOD_PKA_2 150 156 PF00069 0.566
MOD_PKA_2 287 293 PF00069 0.377
MOD_PKA_2 337 343 PF00069 0.435
MOD_PKA_2 379 385 PF00069 0.678
MOD_PKA_2 635 641 PF00069 0.369
MOD_PKA_2 7 13 PF00069 0.561
MOD_PKA_2 751 757 PF00069 0.384
MOD_PKA_2 867 873 PF00069 0.400
MOD_PKA_2 983 989 PF00069 0.386
MOD_PKB_1 16 24 PF00069 0.575
MOD_PKB_1 172 180 PF00069 0.555
MOD_Plk_1 193 199 PF00069 0.471
MOD_Plk_1 27 33 PF00069 0.511
MOD_Plk_1 273 279 PF00069 0.395
MOD_Plk_1 319 325 PF00069 0.589
MOD_Plk_1 350 356 PF00069 0.430
MOD_Plk_1 444 450 PF00069 0.390
MOD_Plk_2-3 180 186 PF00069 0.514
MOD_Plk_4 166 172 PF00069 0.488
MOD_Plk_4 247 253 PF00069 0.632
MOD_Plk_4 292 298 PF00069 0.564
MOD_Plk_4 356 362 PF00069 0.439
MOD_Plk_4 516 522 PF00069 0.548
MOD_Plk_4 98 104 PF00069 0.576
MOD_ProDKin_1 108 114 PF00069 0.548
MOD_ProDKin_1 1181 1187 PF00069 0.490
MOD_ProDKin_1 129 135 PF00069 0.576
MOD_ProDKin_1 2 8 PF00069 0.550
MOD_ProDKin_1 296 302 PF00069 0.460
MOD_ProDKin_1 35 41 PF00069 0.504
MOD_ProDKin_1 486 492 PF00069 0.588
MOD_ProDKin_1 500 506 PF00069 0.677
MOD_ProDKin_1 74 80 PF00069 0.568
MOD_ProDKin_1 82 88 PF00069 0.553
MOD_SUMO_for_1 1093 1096 PF00179 0.370
MOD_SUMO_for_1 629 632 PF00179 0.433
MOD_SUMO_for_1 745 748 PF00179 0.379
MOD_SUMO_for_1 861 864 PF00179 0.448
MOD_SUMO_for_1 977 980 PF00179 0.390
MOD_SUMO_rev_2 1033 1043 PF00179 0.370
MOD_SUMO_rev_2 1149 1159 PF00179 0.385
MOD_SUMO_rev_2 1254 1259 PF00179 0.420
MOD_SUMO_rev_2 1300 1309 PF00179 0.430
MOD_SUMO_rev_2 569 579 PF00179 0.374
MOD_SUMO_rev_2 685 695 PF00179 0.369
MOD_SUMO_rev_2 801 811 PF00179 0.378
MOD_SUMO_rev_2 917 927 PF00179 0.385
TRG_DiLeu_BaEn_1 452 457 PF01217 0.422
TRG_DiLeu_BaEn_4 432 438 PF01217 0.413
TRG_DiLeu_BaEn_4 44 50 PF01217 0.540
TRG_DiLeu_BaLyEn_6 1182 1187 PF01217 0.455
TRG_ENDOCYTIC_2 1295 1298 PF00928 0.456
TRG_ENDOCYTIC_2 293 296 PF00928 0.607
TRG_ENDOCYTIC_2 446 449 PF00928 0.437
TRG_ER_diArg_1 1223 1225 PF00400 0.414
TRG_ER_diArg_1 1236 1238 PF00400 0.344
TRG_ER_diArg_1 15 18 PF00400 0.576
TRG_ER_diArg_1 171 174 PF00400 0.556
TRG_ER_diArg_1 277 280 PF00400 0.395
TRG_ER_diArg_1 337 339 PF00400 0.458
TRG_NES_CRM1_1 388 399 PF08389 0.444
TRG_Pf-PMV_PEXEL_1 1103 1107 PF00026 0.407
TRG_Pf-PMV_PEXEL_1 1277 1282 PF00026 0.413
TRG_Pf-PMV_PEXEL_1 1304 1308 PF00026 0.443
TRG_Pf-PMV_PEXEL_1 1321 1325 PF00026 0.435
TRG_Pf-PMV_PEXEL_1 316 320 PF00026 0.539
TRG_Pf-PMV_PEXEL_1 337 341 PF00026 0.472
TRG_Pf-PMV_PEXEL_1 344 349 PF00026 0.432
TRG_Pf-PMV_PEXEL_1 425 430 PF00026 0.422
TRG_Pf-PMV_PEXEL_1 639 643 PF00026 0.418
TRG_Pf-PMV_PEXEL_1 755 759 PF00026 0.427
TRG_Pf-PMV_PEXEL_1 871 875 PF00026 0.442
TRG_Pf-PMV_PEXEL_1 987 991 PF00026 0.429

Homologs

Protein Taxonomy Sequence identity Coverage
E9B547 Leishmania mexicana (strain MHOM/GT/2001/U1103) 79% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS