T. brucei spp.-specific protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania infantum

UniProt:

A4IA27_LEIIN

TriTrypDb:

LINF_340031000

Length:

259

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IA27

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IA27

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	246	248	PF00675	0.575
CLV_NRD_NRD_1	48	50	PF00675	0.530
CLV_NRD_NRD_1	84	86	PF00675	0.471
CLV_PCSK_FUR_1	244	248	PF00082	0.590
CLV_PCSK_KEX2_1	240	242	PF00082	0.587
CLV_PCSK_KEX2_1	246	248	PF00082	0.565
CLV_PCSK_KEX2_1	84	86	PF00082	0.471
CLV_PCSK_PC1ET2_1	240	242	PF00082	0.587
CLV_PCSK_SKI1_1	122	126	PF00082	0.486
CLV_PCSK_SKI1_1	137	141	PF00082	0.455
CLV_PCSK_SKI1_1	30	34	PF00082	0.561
CLV_PCSK_SKI1_1	53	57	PF00082	0.537
DEG_Nend_UBRbox_4	1	3	PF02207	0.510
DEG_SCF_FBW7_1	203	208	PF00400	0.510
DEG_SPOP_SBC_1	75	79	PF00917	0.516
DOC_CKS1_1	202	207	PF01111	0.509
DOC_MAPK_FxFP_2	166	169	PF00069	0.482
DOC_MAPK_gen_1	74	82	PF00069	0.542
DOC_MAPK_gen_1	84	93	PF00069	0.386
DOC_MAPK_MEF2A_6	57	64	PF00069	0.498
DOC_MAPK_MEF2A_6	84	93	PF00069	0.427
DOC_PP1_RVXF_1	120	127	PF00149	0.492
DOC_PP2B_PxIxI_1	59	65	PF00149	0.461
DOC_PP4_FxxP_1	152	155	PF00568	0.506
DOC_PP4_FxxP_1	166	169	PF00568	0.544
DOC_SPAK_OSR1_1	104	108	PF12202	0.422
DOC_USP7_MATH_1	227	231	PF00917	0.754
DOC_WW_Pin1_4	150	155	PF00397	0.547
DOC_WW_Pin1_4	20	25	PF00397	0.499
DOC_WW_Pin1_4	201	206	PF00397	0.504
DOC_WW_Pin1_4	208	213	PF00397	0.495
DOC_WW_Pin1_4	215	220	PF00397	0.490
DOC_WW_Pin1_4	245	250	PF00397	0.553
DOC_WW_Pin1_4	92	97	PF00397	0.446
LIG_14-3-3_CanoR_1	143	149	PF00244	0.579
LIG_14-3-3_CanoR_1	220	227	PF00244	0.553
LIG_14-3-3_CanoR_1	74	82	PF00244	0.542
LIG_BRCT_BRCA1_1	164	168	PF00533	0.478
LIG_BRCT_BRCA1_1	78	82	PF00533	0.485
LIG_FHA_1	46	52	PF00498	0.621
LIG_FHA_1	54	60	PF00498	0.517
LIG_LIR_Apic_2	165	169	PF02991	0.540
LIG_LIR_Apic_2	201	205	PF02991	0.502
LIG_LIR_Gen_1	161	171	PF02991	0.484
LIG_LIR_Gen_1	204	212	PF02991	0.513
LIG_LIR_Gen_1	86	96	PF02991	0.424
LIG_LIR_Nem_3	156	160	PF02991	0.496
LIG_LIR_Nem_3	161	167	PF02991	0.466
LIG_LIR_Nem_3	170	174	PF02991	0.428
LIG_LIR_Nem_3	204	209	PF02991	0.512
LIG_LIR_Nem_3	86	91	PF02991	0.411
LIG_PCNA_yPIPBox_3	246	259	PF02747	0.542
LIG_PCNA_yPIPBox_3	33	46	PF02747	0.482
LIG_Pex14_1	202	206	PF04695	0.507
LIG_Pex14_2	162	166	PF04695	0.478
LIG_SH2_CRK	157	161	PF00017	0.496
LIG_SH2_SRC	148	151	PF00017	0.507
LIG_SH2_STAP1	148	152	PF00017	0.508
LIG_SH2_STAT5	88	91	PF00017	0.443
LIG_SH3_3	88	94	PF00018	0.412
LIG_SUMO_SIM_anti_2	61	68	PF11976	0.518
LIG_TRAF2_1	231	234	PF00917	0.556
LIG_WW_1	154	157	PF00397	0.500
MOD_CDK_SPK_2	215	220	PF00069	0.534
MOD_CDK_SPxK_1	245	251	PF00069	0.552
MOD_CDK_SPxxK_3	208	215	PF00069	0.518
MOD_CDK_SPxxK_3	92	99	PF00069	0.455
MOD_CK1_1	158	164	PF00069	0.486
MOD_CK1_1	201	207	PF00069	0.506
MOD_CK1_1	218	224	PF00069	0.496
MOD_CK1_1	245	251	PF00069	0.797
MOD_CK2_1	218	224	PF00069	0.662
MOD_CK2_1	227	233	PF00069	0.537
MOD_CK2_1	80	86	PF00069	0.628
MOD_GlcNHglycan	229	232	PF01048	0.568
MOD_GSK3_1	158	165	PF00069	0.717
MOD_GSK3_1	201	208	PF00069	0.692
MOD_GSK3_1	76	83	PF00069	0.501
MOD_N-GLC_1	38	43	PF02516	0.492
MOD_NEK2_1	162	167	PF00069	0.685
MOD_PIKK_1	239	245	PF00454	0.597
MOD_PKA_2	227	233	PF00069	0.557
MOD_PKA_2	75	81	PF00069	0.509
MOD_PKB_1	74	82	PF00069	0.501
MOD_Plk_1	169	175	PF00069	0.546
MOD_Plk_4	38	44	PF00069	0.478
MOD_ProDKin_1	150	156	PF00069	0.545
MOD_ProDKin_1	20	26	PF00069	0.500
MOD_ProDKin_1	201	207	PF00069	0.506
MOD_ProDKin_1	208	214	PF00069	0.495
MOD_ProDKin_1	215	221	PF00069	0.491
MOD_ProDKin_1	245	251	PF00069	0.552
MOD_ProDKin_1	92	98	PF00069	0.451
MOD_SUMO_rev_2	67	73	PF00179	0.534
TRG_DiLeu_BaEn_1	120	125	PF01217	0.491
TRG_ENDOCYTIC_2	157	160	PF00928	0.498
TRG_ENDOCYTIC_2	88	91	PF00928	0.402
TRG_ER_diArg_1	180	183	PF00400	0.472
TRG_ER_diArg_1	244	247	PF00400	0.606
TRG_ER_diArg_1	73	76	PF00400	0.572

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9B542	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	92%