Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IA14_LEIIN

TriTrypDb:

LINF_340028900

Length:

206

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IA14

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IA14

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	182	184	PF00675	0.555
CLV_NRD_NRD_1	48	50	PF00675	0.574
CLV_NRD_NRD_1	80	82	PF00675	0.587
CLV_PCSK_FUR_1	46	50	PF00082	0.579
CLV_PCSK_KEX2_1	182	184	PF00082	0.555
CLV_PCSK_KEX2_1	48	50	PF00082	0.552
CLV_PCSK_SKI1_1	38	42	PF00082	0.581
DOC_CYCLIN_RxL_1	167	178	PF00134	0.474
DOC_MAPK_gen_1	99	108	PF00069	0.749
DOC_USP7_MATH_1	12	16	PF00917	0.611
DOC_USP7_MATH_1	161	165	PF00917	0.431
DOC_USP7_MATH_1	26	30	PF00917	0.616
DOC_USP7_MATH_1	80	84	PF00917	0.577
LIG_14-3-3_CanoR_1	101	107	PF00244	0.524
LIG_14-3-3_CanoR_1	95	99	PF00244	0.653
LIG_BIR_II_1	1	5	PF00653	0.674
LIG_eIF4E_1	199	205	PF01652	0.657
LIG_FHA_1	103	109	PF00498	0.742
LIG_FHA_1	113	119	PF00498	0.590
LIG_FHA_1	121	127	PF00498	0.480
LIG_FHA_1	186	192	PF00498	0.707
LIG_FHA_2	187	193	PF00498	0.597
LIG_LIR_Gen_1	59	68	PF02991	0.544
LIG_LIR_Nem_3	192	196	PF02991	0.564
LIG_LIR_Nem_3	59	63	PF02991	0.512
LIG_SH2_NCK_1	199	203	PF00017	0.693
LIG_SH2_STAP1	96	100	PF00017	0.671
LIG_SH2_STAT5	96	99	PF00017	0.671
LIG_SH3_3	85	91	PF00018	0.779
LIG_SUMO_SIM_anti_2	104	110	PF11976	0.743
LIG_SUMO_SIM_anti_2	62	67	PF11976	0.436
MOD_CK1_1	14	20	PF00069	0.683
MOD_GSK3_1	11	18	PF00069	0.686
MOD_LATS_1	9	15	PF00433	0.689
MOD_N-GLC_1	118	123	PF02516	0.654
MOD_N-GLC_1	185	190	PF02516	0.596
MOD_NEK2_1	118	123	PF00069	0.616
MOD_NEK2_1	185	190	PF00069	0.689
MOD_NEK2_1	19	24	PF00069	0.683
MOD_NEK2_1	191	196	PF00069	0.650
MOD_PK_1	48	54	PF00069	0.565
MOD_PKA_1	48	54	PF00069	0.565
MOD_PKA_2	48	54	PF00069	0.643
MOD_PKA_2	80	86	PF00069	0.600
MOD_PKA_2	91	97	PF00069	0.543
MOD_PKB_1	46	54	PF00069	0.570
MOD_PKB_1	99	107	PF00069	0.574
MOD_Plk_1	191	197	PF00069	0.726
MOD_Plk_1	61	67	PF00069	0.434
MOD_Plk_4	104	110	PF00069	0.683
MOD_Plk_4	161	167	PF00069	0.586
MOD_Plk_4	61	67	PF00069	0.438
TRG_ER_diArg_1	182	184	PF00400	0.555
TRG_ER_diArg_1	47	49	PF00400	0.577

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IC33	Leptomonas seymouri	32%	100%
A0A3Q8IHA0	Leishmania donovani	99%	100%
A4HAU7	Leishmania braziliensis	59%	100%
E9B521	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4Q2W5	Leishmania major	89%	100%