LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IA02_LEIIN
TriTrypDb:
LINF_340029800
Length:
188

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IA02
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IA02

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 167 171 PF00656 0.565
CLV_NRD_NRD_1 180 182 PF00675 0.638
CLV_NRD_NRD_1 31 33 PF00675 0.488
CLV_PCSK_KEX2_1 182 184 PF00082 0.628
CLV_PCSK_PC1ET2_1 182 184 PF00082 0.653
CLV_PCSK_SKI1_1 182 186 PF00082 0.612
CLV_PCSK_SKI1_1 33 37 PF00082 0.449
DEG_SPOP_SBC_1 115 119 PF00917 0.645
DOC_ANK_TNKS_1 145 152 PF00023 0.463
DOC_CKS1_1 15 20 PF01111 0.473
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I235 Leptomonas seymouri 71% 100%
A0A0S4INZ5 Bodo saltans 40% 94%
A0A1X0P9P7 Trypanosomatidae 58% 100%
A0A3R7KWP6 Trypanosoma rangeli 53% 100%
A0A3S7X7Y8 Leishmania donovani 98% 100%
A4HAV5 Leishmania braziliensis 87% 100%
C9ZMK8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 51% 100%
E9B530 Leishmania mexicana (strain MHOM/GT/2001/U1103) 95% 100%
Q4Q2V6 Leishmania major 96% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS