Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Aminotransferase class IV - putative

Species:

Leishmania infantum

UniProt:

A4I9Z9_LEIIN

TriTrypDb:

LINF_340029500

Length:

385

Annotations

Annotations by Jardim et al.

Amino acid metabolism, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Show entries

Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	1
GO:0005737	cytoplasm	2	1
GO:0016020	membrane	2	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	2

Previous1Next

Expansion

Sequence features

A4I9Z9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I9Z9

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006082	organic acid metabolic process	3	1
GO:0008152	metabolic process	1	1
GO:0009987	cellular process	1	1
GO:0019752	carboxylic acid metabolic process	5	1
GO:0043436	oxoacid metabolic process	4	1
GO:0044237	cellular metabolic process	2	1
GO:0044281	small molecule metabolic process	2	1
GO:0071704	organic substance metabolic process	2	1

Previous1Next

Show entries

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	11
GO:0008483	transaminase activity	4	1
GO:0016740	transferase activity	2	1
GO:0016769	transferase activity, transferring nitrogenous groups	3	1

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	242	246	PF00656	0.576
CLV_NRD_NRD_1	335	337	PF00675	0.460
CLV_NRD_NRD_1	40	42	PF00675	0.470
CLV_PCSK_KEX2_1	335	337	PF00082	0.460
CLV_PCSK_KEX2_1	40	42	PF00082	0.433
CLV_PCSK_SKI1_1	155	159	PF00082	0.304
CLV_PCSK_SKI1_1	303	307	PF00082	0.329
CLV_PCSK_SKI1_1	309	313	PF00082	0.260
DEG_Nend_UBRbox_1	1	4	PF02207	0.450
DOC_CYCLIN_yCln2_LP_2	119	125	PF00134	0.453

Previous1 2 3 4 5…13Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDK5	Leptomonas seymouri	63%	100%
A0A1X0PAI4	Trypanosomatidae	38%	100%
A0A3Q8IUN5	Leishmania donovani	98%	100%
A0A3R7NT31	Trypanosoma rangeli	35%	100%
A4HAV2	Leishmania braziliensis	83%	100%
C9ZML4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	99%
E9B527	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4Q2V9	Leishmania major	90%	100%
V5B0F3	Trypanosoma cruzi	33%	82%

Previous1Next