Endo/exonuclease/phosphatase domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Endonuclease/Exonuclease/phosphatase family - putative

Species:

Leishmania infantum

UniProt:

A4I9Z4_LEIIN

TriTrypDb:

LINF_340027600

Length:

832

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4I9Z4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I9Z4

Function

Biological processes
Term	Name	Level	Count
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	6	1
GO:0000956	nuclear-transcribed mRNA catabolic process	7	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006401	RNA catabolic process	5	1
GO:0006402	mRNA catabolic process	6	1
GO:0006417	regulation of translation	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009056	catabolic process	2	1
GO:0009057	macromolecule catabolic process	4	1
GO:0009889	regulation of biosynthetic process	4	1
GO:0009890	negative regulation of biosynthetic process	5	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0009893	positive regulation of metabolic process	4	1
GO:0009894	regulation of catabolic process	4	1
GO:0009896	positive regulation of catabolic process	5	1
GO:0009987	cellular process	1	1
GO:0010468	regulation of gene expression	5	1
GO:0010556	regulation of macromolecule biosynthetic process	5	1
GO:0010558	negative regulation of macromolecule biosynthetic process	6	1
GO:0010604	positive regulation of macromolecule metabolic process	5	1
GO:0010605	negative regulation of macromolecule metabolic process	5	1
GO:0010608	post-transcriptional regulation of gene expression	6	1
GO:0010629	negative regulation of gene expression	6	1
GO:0016070	RNA metabolic process	5	1
GO:0016071	mRNA metabolic process	6	1
GO:0017148	negative regulation of translation	7	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0019439	aromatic compound catabolic process	4	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031324	negative regulation of cellular metabolic process	5	1
GO:0031325	positive regulation of cellular metabolic process	5	1
GO:0031326	regulation of cellular biosynthetic process	5	1
GO:0031327	negative regulation of cellular biosynthetic process	6	1
GO:0031329	regulation of cellular catabolic process	5	1
GO:0031331	positive regulation of cellular catabolic process	6	1
GO:0034248	regulation of amide metabolic process	5	1
GO:0034249	negative regulation of amide metabolic process	6	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034655	nucleobase-containing compound catabolic process	4	1
GO:0043170	macromolecule metabolic process	3	1
GO:0043487	regulation of RNA stability	3	1
GO:0043488	regulation of mRNA stability	4	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044248	cellular catabolic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0044265	obsolete cellular macromolecule catabolic process	4	1
GO:0044270	cellular nitrogen compound catabolic process	4	1
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	6	1
GO:0046483	heterocycle metabolic process	3	1
GO:0046700	heterocycle catabolic process	4	1
GO:0048518	positive regulation of biological process	3	1
GO:0048519	negative regulation of biological process	3	1
GO:0048522	positive regulation of cellular process	4	1
GO:0048523	negative regulation of cellular process	4	1
GO:0050779	RNA destabilization	4	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051172	negative regulation of nitrogen compound metabolic process	5	1
GO:0051173	positive regulation of nitrogen compound metabolic process	5	1
GO:0051246	regulation of protein metabolic process	5	1
GO:0051248	negative regulation of protein metabolic process	6	1
GO:0051252	regulation of RNA metabolic process	5	1
GO:0051254	positive regulation of RNA metabolic process	6	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0061013	regulation of mRNA catabolic process	6	1
GO:0061014	positive regulation of mRNA catabolic process	7	1
GO:0061157	mRNA destabilization	5	1
GO:0065007	biological regulation	1	1
GO:0065008	regulation of biological quality	2	1
GO:0071704	organic substance metabolic process	2	1
GO:0080090	regulation of primary metabolic process	4	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1
GO:1901361	organic cyclic compound catabolic process	4	1
GO:1901575	organic substance catabolic process	3	1
GO:1903311	regulation of mRNA metabolic process	6	1
GO:1903313	positive regulation of mRNA metabolic process	7	1
GO:2000112	obsolete regulation of cellular macromolecule biosynthetic process	6	1
GO:2000113	obsolete negative regulation of cellular macromolecule biosynthetic process	7	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	12
GO:0000175	3'-5'-RNA exonuclease activity	7	1
GO:0004518	nuclease activity	4	2
GO:0004527	exonuclease activity	5	2
GO:0004532	RNA exonuclease activity	5	1
GO:0004540	RNA nuclease activity	4	1
GO:0008408	3'-5' exonuclease activity	6	1
GO:0016787	hydrolase activity	2	2
GO:0016788	hydrolase activity, acting on ester bonds	3	2
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6	1
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	6	1
GO:0140098	catalytic activity, acting on RNA	3	1
GO:0140640	catalytic activity, acting on a nucleic acid	2	1
GO:0004519	endonuclease activity	5	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	23	27	PF00656	0.574
CLV_MEL_PAP_1	533	539	PF00089	0.340
CLV_NRD_NRD_1	447	449	PF00675	0.340
CLV_NRD_NRD_1	623	625	PF00675	0.405
CLV_NRD_NRD_1	693	695	PF00675	0.416
CLV_NRD_NRD_1	700	702	PF00675	0.437
CLV_NRD_NRD_1	79	81	PF00675	0.486
CLV_NRD_NRD_1	8	10	PF00675	0.522
CLV_PCSK_FUR_1	621	625	PF00082	0.311
CLV_PCSK_KEX2_1	125	127	PF00082	0.568
CLV_PCSK_KEX2_1	167	169	PF00082	0.735
CLV_PCSK_KEX2_1	623	625	PF00082	0.404
CLV_PCSK_KEX2_1	698	700	PF00082	0.420
CLV_PCSK_KEX2_1	79	81	PF00082	0.486
CLV_PCSK_KEX2_1	8	10	PF00082	0.522
CLV_PCSK_PC1ET2_1	125	127	PF00082	0.446
CLV_PCSK_PC1ET2_1	167	169	PF00082	0.735
CLV_PCSK_PC1ET2_1	698	700	PF00082	0.405
CLV_PCSK_PC7_1	121	127	PF00082	0.465
CLV_PCSK_PC7_1	619	625	PF00082	0.313
CLV_PCSK_PC7_1	694	700	PF00082	0.433
CLV_PCSK_SKI1_1	121	125	PF00082	0.689
CLV_PCSK_SKI1_1	193	197	PF00082	0.495
CLV_PCSK_SKI1_1	207	211	PF00082	0.552
CLV_PCSK_SKI1_1	413	417	PF00082	0.300
CLV_PCSK_SKI1_1	471	475	PF00082	0.346
CLV_PCSK_SKI1_1	556	560	PF00082	0.316
CLV_PCSK_SKI1_1	57	61	PF00082	0.540
CLV_PCSK_SKI1_1	642	646	PF00082	0.280
CLV_PCSK_SKI1_1	683	687	PF00082	0.223
CLV_PCSK_SKI1_1	740	744	PF00082	0.349
CLV_Separin_Metazoa	792	796	PF03568	0.421
DEG_Nend_Nbox_1	1	3	PF02207	0.573
DEG_SCF_FBW7_1	91	98	PF00400	0.503
DEG_SPOP_SBC_1	113	117	PF00917	0.738
DOC_CYCLIN_RxL_1	118	127	PF00134	0.483
DOC_MAPK_MEF2A_6	187	196	PF00069	0.453
DOC_MAPK_MEF2A_6	366	374	PF00069	0.506
DOC_PP1_RVXF_1	191	197	PF00149	0.474
DOC_PP1_RVXF_1	267	273	PF00149	0.381
DOC_PP1_RVXF_1	658	664	PF00149	0.399
DOC_PP2B_LxvP_1	195	198	PF13499	0.546
DOC_PP2B_LxvP_1	240	243	PF13499	0.531
DOC_PP2B_LxvP_1	393	396	PF13499	0.578
DOC_PP2B_LxvP_1	766	769	PF13499	0.458
DOC_PP4_FxxP_1	196	199	PF00568	0.573
DOC_PP4_FxxP_1	809	812	PF00568	0.421
DOC_USP7_MATH_1	100	104	PF00917	0.756
DOC_USP7_MATH_1	108	112	PF00917	0.490
DOC_USP7_MATH_1	113	117	PF00917	0.690
DOC_USP7_MATH_1	139	143	PF00917	0.447
DOC_USP7_MATH_1	19	23	PF00917	0.568
DOC_USP7_MATH_1	199	203	PF00917	0.598
DOC_USP7_MATH_1	312	316	PF00917	0.391
DOC_USP7_MATH_1	334	338	PF00917	0.608
DOC_USP7_MATH_1	39	43	PF00917	0.554
DOC_USP7_MATH_1	549	553	PF00917	0.443
DOC_USP7_MATH_1	61	65	PF00917	0.569
DOC_USP7_MATH_1	612	616	PF00917	0.431
DOC_USP7_MATH_1	720	724	PF00917	0.416
DOC_USP7_MATH_1	798	802	PF00917	0.417
DOC_USP7_MATH_1	90	94	PF00917	0.728
DOC_USP7_UBL2_3	207	211	PF12436	0.648
DOC_USP7_UBL2_3	53	57	PF12436	0.602
DOC_USP7_UBL2_3	698	702	PF12436	0.313
DOC_WW_Pin1_4	109	114	PF00397	0.516
DOC_WW_Pin1_4	296	301	PF00397	0.532
DOC_WW_Pin1_4	355	360	PF00397	0.375
DOC_WW_Pin1_4	40	45	PF00397	0.659
DOC_WW_Pin1_4	402	407	PF00397	0.539
DOC_WW_Pin1_4	59	64	PF00397	0.507
DOC_WW_Pin1_4	600	605	PF00397	0.365
DOC_WW_Pin1_4	608	613	PF00397	0.298
DOC_WW_Pin1_4	708	713	PF00397	0.432
DOC_WW_Pin1_4	91	96	PF00397	0.609
LIG_14-3-3_CanoR_1	168	174	PF00244	0.635
LIG_14-3-3_CanoR_1	18	25	PF00244	0.489
LIG_14-3-3_CanoR_1	226	233	PF00244	0.510
LIG_14-3-3_CanoR_1	371	375	PF00244	0.496
LIG_14-3-3_CanoR_1	413	418	PF00244	0.304
LIG_14-3-3_CanoR_1	642	649	PF00244	0.421
LIG_14-3-3_CanoR_1	701	710	PF00244	0.274
LIG_Actin_WH2_2	546	562	PF00022	0.223
LIG_APCC_ABBA_1	135	140	PF00400	0.470
LIG_APCC_ABBAyCdc20_2	211	217	PF00400	0.513
LIG_BRCT_BRCA1_1	314	318	PF00533	0.466
LIG_BRCT_BRCA1_1	526	530	PF00533	0.391
LIG_BRCT_BRCA1_1	64	68	PF00533	0.584
LIG_eIF4E_1	672	678	PF01652	0.287
LIG_FHA_1	102	108	PF00498	0.729
LIG_FHA_1	168	174	PF00498	0.570
LIG_FHA_1	244	250	PF00498	0.551
LIG_FHA_1	358	364	PF00498	0.423
LIG_FHA_1	402	408	PF00498	0.410
LIG_FHA_1	414	420	PF00498	0.295
LIG_FHA_1	437	443	PF00498	0.259
LIG_FHA_1	459	465	PF00498	0.345
LIG_FHA_1	644	650	PF00498	0.398
LIG_FHA_1	794	800	PF00498	0.286
LIG_FHA_1	86	92	PF00498	0.504
LIG_FHA_2	21	27	PF00498	0.570
LIG_FHA_2	701	707	PF00498	0.374
LIG_FHA_2	709	715	PF00498	0.356
LIG_FHA_2	774	780	PF00498	0.319
LIG_LIR_Apic_2	476	480	PF02991	0.405
LIG_LIR_Apic_2	806	812	PF02991	0.424
LIG_LIR_Gen_1	256	267	PF02991	0.545
LIG_LIR_Gen_1	327	336	PF02991	0.470
LIG_LIR_Gen_1	378	389	PF02991	0.400
LIG_LIR_Gen_1	416	424	PF02991	0.280
LIG_LIR_Gen_1	508	519	PF02991	0.343
LIG_LIR_Gen_1	767	777	PF02991	0.389
LIG_LIR_Gen_1	782	791	PF02991	0.236
LIG_LIR_Nem_3	256	262	PF02991	0.469
LIG_LIR_Nem_3	327	331	PF02991	0.395
LIG_LIR_Nem_3	345	351	PF02991	0.519
LIG_LIR_Nem_3	416	420	PF02991	0.296
LIG_LIR_Nem_3	472	477	PF02991	0.341
LIG_LIR_Nem_3	508	514	PF02991	0.343
LIG_LIR_Nem_3	527	533	PF02991	0.486
LIG_LIR_Nem_3	638	644	PF02991	0.299
LIG_LIR_Nem_3	767	773	PF02991	0.308
LIG_LIR_Nem_3	774	780	PF02991	0.295
LIG_LIR_Nem_3	782	786	PF02991	0.287
LIG_NRBOX	676	682	PF00104	0.414
LIG_PCNA_yPIPBox_3	276	288	PF02747	0.362
LIG_Pex14_2	474	478	PF04695	0.382
LIG_Pex14_2	773	777	PF04695	0.421
LIG_PTB_Apo_2	265	272	PF02174	0.325
LIG_PTB_Apo_2	810	817	PF02174	0.295
LIG_PTB_Phospho_1	810	816	PF10480	0.295
LIG_SH2_CRK	289	293	PF00017	0.358
LIG_SH2_CRK	417	421	PF00017	0.280
LIG_SH2_CRK	487	491	PF00017	0.374
LIG_SH2_CRK	590	594	PF00017	0.295
LIG_SH2_CRK	641	645	PF00017	0.295
LIG_SH2_NCK_1	289	293	PF00017	0.347
LIG_SH2_PTP2	304	307	PF00017	0.357
LIG_SH2_STAP1	326	330	PF00017	0.295
LIG_SH2_STAT3	751	754	PF00017	0.365
LIG_SH2_STAT5	304	307	PF00017	0.324
LIG_SH2_STAT5	477	480	PF00017	0.419
LIG_SH2_STAT5	491	494	PF00017	0.306
LIG_SH2_STAT5	783	786	PF00017	0.327
LIG_SH3_1	619	625	PF00018	0.287
LIG_SH3_2	163	168	PF14604	0.649
LIG_SH3_2	264	269	PF14604	0.281
LIG_SH3_3	133	139	PF00018	0.371
LIG_SH3_3	150	156	PF00018	0.285
LIG_SH3_3	160	166	PF00018	0.773
LIG_SH3_3	245	251	PF00018	0.448
LIG_SH3_3	261	267	PF00018	0.380
LIG_SH3_3	297	303	PF00018	0.360
LIG_SH3_3	392	398	PF00018	0.494
LIG_SH3_3	404	410	PF00018	0.341
LIG_SH3_3	619	625	PF00018	0.414
LIG_SH3_3	709	715	PF00018	0.305
LIG_SH3_3	794	800	PF00018	0.297
LIG_SH3_CIN85_PxpxPR_1	394	399	PF14604	0.427
LIG_SUMO_SIM_anti_2	313	318	PF11976	0.440
LIG_SUMO_SIM_anti_2	675	682	PF11976	0.287
LIG_SUMO_SIM_anti_2	787	796	PF11976	0.302
LIG_SUMO_SIM_anti_2	818	826	PF11976	0.331
LIG_SUMO_SIM_par_1	142	148	PF11976	0.393
LIG_SUMO_SIM_par_1	293	299	PF11976	0.547
LIG_SUMO_SIM_par_1	439	446	PF11976	0.285
LIG_TRAF2_1	178	181	PF00917	0.552
LIG_TYR_ITIM	302	307	PF00017	0.462
LIG_TYR_ITIM	415	420	PF00017	0.295
LIG_UBA3_1	442	449	PF00899	0.351
LIG_WW_3	197	201	PF00397	0.612
MOD_CDK_SPxK_1	91	97	PF00069	0.501
MOD_CK1_1	101	107	PF00069	0.683
MOD_CK1_1	109	115	PF00069	0.791
MOD_CK1_1	202	208	PF00069	0.564
MOD_CK1_1	296	302	PF00069	0.532
MOD_CK1_1	320	326	PF00069	0.443
MOD_CK1_1	332	338	PF00069	0.551
MOD_CK1_1	427	433	PF00069	0.318
MOD_CK1_1	548	554	PF00069	0.382
MOD_CK1_1	597	603	PF00069	0.402
MOD_CK1_1	62	68	PF00069	0.737
MOD_CK1_1	704	710	PF00069	0.355
MOD_CK1_1	723	729	PF00069	0.389
MOD_CK1_1	787	793	PF00069	0.380
MOD_CK1_1	82	88	PF00069	0.645
MOD_CK1_1	93	99	PF00069	0.719
MOD_CK2_1	249	255	PF00069	0.500
MOD_CK2_1	494	500	PF00069	0.432
MOD_CK2_1	561	567	PF00069	0.315
MOD_CK2_1	700	706	PF00069	0.419
MOD_CK2_1	773	779	PF00069	0.321
MOD_CK2_1	798	804	PF00069	0.405
MOD_GlcNHglycan	116	119	PF01048	0.729
MOD_GlcNHglycan	201	204	PF01048	0.596
MOD_GlcNHglycan	333	337	PF01048	0.641
MOD_GlcNHglycan	339	342	PF01048	0.686
MOD_GlcNHglycan	494	497	PF01048	0.353
MOD_GlcNHglycan	547	550	PF01048	0.428
MOD_GlcNHglycan	64	67	PF01048	0.660
MOD_GlcNHglycan	703	706	PF01048	0.329
MOD_GSK3_1	108	115	PF00069	0.667
MOD_GSK3_1	13	20	PF00069	0.589
MOD_GSK3_1	139	146	PF00069	0.410
MOD_GSK3_1	167	174	PF00069	0.635
MOD_GSK3_1	181	188	PF00069	0.498
MOD_GSK3_1	198	205	PF00069	0.447
MOD_GSK3_1	21	28	PF00069	0.601
MOD_GSK3_1	249	256	PF00069	0.627
MOD_GSK3_1	353	360	PF00069	0.533
MOD_GSK3_1	375	382	PF00069	0.417
MOD_GSK3_1	39	46	PF00069	0.662
MOD_GSK3_1	423	430	PF00069	0.386
MOD_GSK3_1	53	60	PF00069	0.495
MOD_GSK3_1	545	552	PF00069	0.390
MOD_GSK3_1	608	615	PF00069	0.398
MOD_GSK3_1	67	74	PF00069	0.762
MOD_GSK3_1	700	707	PF00069	0.397
MOD_GSK3_1	764	771	PF00069	0.438
MOD_GSK3_1	91	98	PF00069	0.750
MOD_N-GLC_1	280	285	PF02516	0.474
MOD_N-GLC_1	492	497	PF02516	0.374
MOD_N-GLC_1	632	637	PF02516	0.280
MOD_N-GLC_1	723	728	PF02516	0.491
MOD_N-GLC_1	771	776	PF02516	0.315
MOD_N-GLC_1	82	87	PF02516	0.427
MOD_N-GLC_2	580	582	PF02516	0.280
MOD_NEK2_1	12	17	PF00069	0.614
MOD_NEK2_1	124	129	PF00069	0.530
MOD_NEK2_1	253	258	PF00069	0.496
MOD_NEK2_1	424	429	PF00069	0.329
MOD_NEK2_1	506	511	PF00069	0.376
MOD_NEK2_1	559	564	PF00069	0.477
MOD_NEK2_1	632	637	PF00069	0.313
MOD_NEK2_1	643	648	PF00069	0.295
MOD_NEK2_1	773	778	PF00069	0.400
MOD_NEK2_1	827	832	PF00069	0.457
MOD_PIKK_1	139	145	PF00454	0.484
MOD_PIKK_1	723	729	PF00454	0.441
MOD_PIKK_1	85	91	PF00454	0.541
MOD_PK_1	385	391	PF00069	0.336
MOD_PK_1	494	500	PF00069	0.421
MOD_PKA_1	167	173	PF00069	0.678
MOD_PKA_1	53	59	PF00069	0.546
MOD_PKA_1	701	707	PF00069	0.396
MOD_PKA_1	79	85	PF00069	0.489
MOD_PKA_2	167	173	PF00069	0.655
MOD_PKA_2	17	23	PF00069	0.484
MOD_PKA_2	199	205	PF00069	0.605
MOD_PKA_2	225	231	PF00069	0.539
MOD_PKA_2	370	376	PF00069	0.493
MOD_PKA_2	506	512	PF00069	0.341
MOD_PKA_2	559	565	PF00069	0.458
MOD_PKA_2	700	706	PF00069	0.281
MOD_PKA_2	79	85	PF00069	0.720
MOD_PKB_1	699	707	PF00069	0.223
MOD_PKB_1	9	17	PF00069	0.474
MOD_Plk_1	147	153	PF00069	0.448
MOD_Plk_1	25	31	PF00069	0.631
MOD_Plk_1	253	259	PF00069	0.435
MOD_Plk_1	280	286	PF00069	0.399
MOD_Plk_1	312	318	PF00069	0.465
MOD_Plk_1	46	52	PF00069	0.586
MOD_Plk_1	597	603	PF00069	0.488
MOD_Plk_1	764	770	PF00069	0.357
MOD_Plk_1	771	777	PF00069	0.298
MOD_Plk_1	787	793	PF00069	0.315
MOD_Plk_2-3	561	567	PF00069	0.300
MOD_Plk_2-3	652	658	PF00069	0.313
MOD_Plk_4	244	250	PF00069	0.418
MOD_Plk_4	280	286	PF00069	0.360
MOD_Plk_4	290	296	PF00069	0.382
MOD_Plk_4	312	318	PF00069	0.476
MOD_Plk_4	385	391	PF00069	0.336
MOD_Plk_4	46	52	PF00069	0.528
MOD_Plk_4	473	479	PF00069	0.322
MOD_Plk_4	525	531	PF00069	0.461
MOD_Plk_4	597	603	PF00069	0.407
MOD_ProDKin_1	109	115	PF00069	0.514
MOD_ProDKin_1	296	302	PF00069	0.531
MOD_ProDKin_1	355	361	PF00069	0.379
MOD_ProDKin_1	40	46	PF00069	0.659
MOD_ProDKin_1	402	408	PF00069	0.542
MOD_ProDKin_1	59	65	PF00069	0.506
MOD_ProDKin_1	600	606	PF00069	0.365
MOD_ProDKin_1	608	614	PF00069	0.298
MOD_ProDKin_1	708	714	PF00069	0.432
MOD_ProDKin_1	91	97	PF00069	0.614
MOD_SUMO_rev_2	174	184	PF00179	0.505
MOD_SUMO_rev_2	679	688	PF00179	0.431
TRG_DiLeu_BaEn_2	499	505	PF01217	0.421
TRG_DiLeu_BaEn_4	235	241	PF01217	0.457
TRG_DiLeu_BaLyEn_6	119	124	PF01217	0.565
TRG_DiLeu_BaLyEn_6	190	195	PF01217	0.469
TRG_DiLeu_BaLyEn_6	639	644	PF01217	0.421
TRG_DiLeu_BaLyEn_6	665	670	PF01217	0.374
TRG_ENDOCYTIC_2	304	307	PF00928	0.377
TRG_ENDOCYTIC_2	409	412	PF00928	0.393
TRG_ENDOCYTIC_2	417	420	PF00928	0.280
TRG_ENDOCYTIC_2	421	424	PF00928	0.285
TRG_ENDOCYTIC_2	487	490	PF00928	0.374
TRG_ENDOCYTIC_2	590	593	PF00928	0.295
TRG_ENDOCYTIC_2	641	644	PF00928	0.280
TRG_ENDOCYTIC_2	783	786	PF00928	0.295
TRG_ER_diArg_1	191	194	PF00400	0.446
TRG_ER_diArg_1	30	33	PF00400	0.519
TRG_ER_diArg_1	619	622	PF00400	0.313
TRG_ER_diArg_1	623	625	PF00400	0.280
TRG_ER_diArg_1	7	9	PF00400	0.518
TRG_ER_diArg_1	79	81	PF00400	0.686
TRG_NES_CRM1_1	789	802	PF08389	0.365
TRG_NLS_MonoCore_2	697	702	PF00514	0.345
TRG_NLS_MonoExtC_3	697	702	PF00514	0.223
TRG_NLS_MonoExtN_4	695	702	PF00514	0.345
TRG_Pf-PMV_PEXEL_1	668	673	PF00026	0.421

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IC26	Leptomonas seymouri	62%	100%
A0A0S4J452	Bodo saltans	32%	100%
A0A1X0PAG3	Trypanosomatidae	43%	100%
A0A3R7LBT2	Trypanosoma rangeli	43%	100%
A0A3S7X813	Leishmania donovani	100%	100%
A4HAT4	Leishmania braziliensis	76%	100%
C9ZMN4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
E9B508	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4Q2X8	Leishmania major	94%	100%
V5DGT6	Trypanosoma cruzi	42%	100%