LeishMANIAdb
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Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Protein kinase domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I9Z3_LEIIN
TriTrypDb:
LINF_340027500 *
Length:
954

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I9Z3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I9Z3

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 283 287 PF00656 0.645
CLV_C14_Caspase3-7 33 37 PF00656 0.666
CLV_NRD_NRD_1 137 139 PF00675 0.602
CLV_NRD_NRD_1 746 748 PF00675 0.709
CLV_NRD_NRD_1 783 785 PF00675 0.649
CLV_NRD_NRD_1 875 877 PF00675 0.559
CLV_NRD_NRD_1 882 884 PF00675 0.552
CLV_PCSK_KEX2_1 137 139 PF00082 0.602
CLV_PCSK_KEX2_1 746 748 PF00082 0.709
CLV_PCSK_KEX2_1 782 784 PF00082 0.642
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S7X7X9 Leishmania donovani 99% 88%
A4HAT3 Leishmania braziliensis 57% 100%
E9B507 Leishmania mexicana (strain MHOM/GT/2001/U1103) 80% 100%
Q4Q2X9 Leishmania major 85% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS