Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I9V0_LEIIN

TriTrypDb:

LINF_340020800

Length:

323

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I9V0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I9V0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	199	203	PF00656	0.456
CLV_C14_Caspase3-7	270	274	PF00656	0.449
CLV_NRD_NRD_1	25	27	PF00675	0.686
CLV_NRD_NRD_1	259	261	PF00675	0.451
CLV_NRD_NRD_1	286	288	PF00675	0.562
CLV_NRD_NRD_1	299	301	PF00675	0.480
CLV_NRD_NRD_1	313	315	PF00675	0.346
CLV_NRD_NRD_1	319	321	PF00675	0.512
CLV_PCSK_KEX2_1	25	27	PF00082	0.699
CLV_PCSK_KEX2_1	286	288	PF00082	0.568
CLV_PCSK_KEX2_1	298	300	PF00082	0.397
CLV_PCSK_KEX2_1	312	314	PF00082	0.489
CLV_PCSK_KEX2_1	318	320	PF00082	0.497
CLV_PCSK_KEX2_1	35	37	PF00082	0.575
CLV_PCSK_PC1ET2_1	318	320	PF00082	0.588
CLV_PCSK_PC1ET2_1	35	37	PF00082	0.611
CLV_PCSK_PC7_1	294	300	PF00082	0.415
CLV_PCSK_PC7_1	314	320	PF00082	0.590
CLV_PCSK_SKI1_1	26	30	PF00082	0.695
CLV_PCSK_SKI1_1	261	265	PF00082	0.501
CLV_PCSK_SKI1_1	314	318	PF00082	0.453
DEG_Nend_Nbox_1	1	3	PF02207	0.629
DOC_CYCLIN_yClb1_LxF_4	73	79	PF00134	0.453
DOC_MAPK_gen_1	60	67	PF00069	0.479
DOC_MAPK_MEF2A_6	85	92	PF00069	0.542
DOC_USP7_MATH_1	18	22	PF00917	0.621
DOC_USP7_MATH_1	8	12	PF00917	0.723
DOC_USP7_UBL2_3	318	322	PF12436	0.620
DOC_WW_Pin1_4	144	149	PF00397	0.639
DOC_WW_Pin1_4	36	41	PF00397	0.572
DOC_WW_Pin1_4	94	99	PF00397	0.694
LIG_14-3-3_CanoR_1	188	196	PF00244	0.491
LIG_14-3-3_CanoR_1	260	264	PF00244	0.533
LIG_APCC_ABBA_1	165	170	PF00400	0.437
LIG_eIF4E_1	159	165	PF01652	0.437
LIG_FHA_1	124	130	PF00498	0.741
LIG_FHA_1	79	85	PF00498	0.479
LIG_FHA_2	126	132	PF00498	0.666
LIG_FHA_2	209	215	PF00498	0.452
LIG_FHA_2	260	266	PF00498	0.564
LIG_LIR_Gen_1	115	123	PF02991	0.576
LIG_LIR_Gen_1	77	88	PF02991	0.652
LIG_LIR_Nem_3	115	119	PF02991	0.567
LIG_LIR_Nem_3	44	50	PF02991	0.478
LIG_PCNA_yPIPBox_3	210	223	PF02747	0.545
LIG_Pex14_2	116	120	PF04695	0.587
LIG_SH2_STAP1	160	164	PF00017	0.410
LIG_SH2_STAP1	80	84	PF00017	0.474
LIG_SH2_STAT5	80	83	PF00017	0.468
LIG_SH3_3	143	149	PF00018	0.601
LIG_SH3_3	4	10	PF00018	0.706
LIG_SH3_4	29	36	PF00018	0.574
LIG_SUMO_SIM_par_1	87	94	PF11976	0.551
LIG_TRAF2_1	172	175	PF00917	0.394
LIG_UBA3_1	119	124	PF00899	0.546
MOD_CK1_1	125	131	PF00069	0.784
MOD_CK1_1	16	22	PF00069	0.755
MOD_CK1_1	94	100	PF00069	0.634
MOD_CK2_1	129	135	PF00069	0.684
MOD_CK2_1	137	143	PF00069	0.644
MOD_CK2_1	16	22	PF00069	0.580
MOD_CK2_1	201	207	PF00069	0.569
MOD_CK2_1	208	214	PF00069	0.524
MOD_CK2_1	222	228	PF00069	0.497
MOD_CK2_1	259	265	PF00069	0.561
MOD_CK2_1	36	42	PF00069	0.534
MOD_CK2_1	66	72	PF00069	0.569
MOD_Cter_Amidation	310	313	PF01082	0.507
MOD_GlcNHglycan	134	138	PF01048	0.638
MOD_GlcNHglycan	15	18	PF01048	0.588
MOD_GlcNHglycan	161	164	PF01048	0.401
MOD_GlcNHglycan	232	235	PF01048	0.414
MOD_GlcNHglycan	273	276	PF01048	0.371
MOD_GlcNHglycan	68	71	PF01048	0.610
MOD_GlcNHglycan	98	101	PF01048	0.609
MOD_GSK3_1	123	130	PF00069	0.662
MOD_GSK3_1	13	20	PF00069	0.700
MOD_GSK3_1	133	140	PF00069	0.597
MOD_GSK3_1	144	151	PF00069	0.542
MOD_GSK3_1	236	243	PF00069	0.474
MOD_GSK3_1	66	73	PF00069	0.597
MOD_N-GLC_1	302	307	PF02516	0.454
MOD_NEK2_1	123	128	PF00069	0.696
MOD_NEK2_1	222	227	PF00069	0.506
MOD_NEK2_1	78	83	PF00069	0.466
MOD_PIKK_1	91	97	PF00454	0.623
MOD_PKA_2	13	19	PF00069	0.610
MOD_PKA_2	259	265	PF00069	0.561
MOD_Plk_1	192	198	PF00069	0.560
MOD_Plk_1	302	308	PF00069	0.454
MOD_Plk_4	259	265	PF00069	0.500
MOD_ProDKin_1	144	150	PF00069	0.635
MOD_ProDKin_1	36	42	PF00069	0.567
MOD_ProDKin_1	94	100	PF00069	0.692
MOD_SUMO_for_1	278	281	PF00179	0.459
MOD_SUMO_for_1	28	31	PF00179	0.691
MOD_SUMO_rev_2	118	126	PF00179	0.561
TRG_DiLeu_BaEn_1	297	302	PF01217	0.487
TRG_DiLeu_BaEn_4	214	220	PF01217	0.570
TRG_DiLeu_BaLyEn_6	85	90	PF01217	0.599
TRG_DiLeu_LyEn_5	297	302	PF01217	0.426
TRG_ENDOCYTIC_2	80	83	PF00928	0.635
TRG_ER_diArg_1	285	287	PF00400	0.566
TRG_ER_diArg_1	298	300	PF00400	0.357
TRG_ER_diArg_1	312	314	PF00400	0.387
TRG_NLS_Bipartite_1	25	39	PF00514	0.658
TRG_NLS_MonoCore_2	317	322	PF00514	0.614
TRG_NLS_MonoExtC_3	317	322	PF00514	0.614
TRG_NLS_MonoExtN_4	34	39	PF00514	0.597
TRG_Pf-PMV_PEXEL_1	304	308	PF00026	0.444

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6R6	Leptomonas seymouri	50%	100%
A0A3Q8IIE4	Leishmania donovani	96%	100%
A4HAQ3	Leishmania braziliensis	70%	100%
E9B4W1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4Q365	Leishmania major	90%	100%