Tuzin-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Tuzin-like protein

Gene product:

tuzin-like protein

Species:

Leishmania infantum

UniProt:

A4I9R8_LEIIN

TriTrypDb:

LINF_340017550

Length:

334

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I9R8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I9R8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	244	246	PF00675	0.546
CLV_PCSK_KEX2_1	244	246	PF00082	0.546
CLV_PCSK_SKI1_1	320	324	PF00082	0.570
DEG_APCC_DBOX_1	73	81	PF00400	0.602
DOC_CYCLIN_yCln2_LP_2	88	94	PF00134	0.610
DOC_PP2B_LxvP_1	88	91	PF13499	0.798
DOC_USP7_MATH_1	272	276	PF00917	0.434
DOC_USP7_MATH_1	9	13	PF00917	0.574
DOC_WW_Pin1_4	12	17	PF00397	0.578
DOC_WW_Pin1_4	314	319	PF00397	0.559
DOC_WW_Pin1_4	68	73	PF00397	0.602
LIG_14-3-3_CanoR_1	104	108	PF00244	0.625
LIG_14-3-3_CanoR_1	111	116	PF00244	0.583
LIG_14-3-3_CanoR_1	273	281	PF00244	0.459
LIG_14-3-3_CanoR_1	304	308	PF00244	0.468
LIG_14-3-3_CanoR_1	312	318	PF00244	0.506
LIG_APCC_ABBA_1	194	199	PF00400	0.628
LIG_BRCT_BRCA1_1	315	319	PF00533	0.560
LIG_FHA_1	28	34	PF00498	0.723
LIG_FHA_1	327	333	PF00498	0.551
LIG_Integrin_RGD_1	157	159	PF01839	0.598
LIG_Integrin_RGDW_4	157	160	PF00362	0.593
LIG_PDZ_Class_2	329	334	PF00595	0.548
LIG_SH2_STAP1	253	257	PF00017	0.550
LIG_SH2_STAT5	253	256	PF00017	0.556
LIG_SH2_STAT5	4	7	PF00017	0.633
LIG_SH3_1	13	19	PF00018	0.586
LIG_SH3_1	315	321	PF00018	0.564
LIG_SH3_2	16	21	PF14604	0.599
LIG_SH3_2	58	63	PF14604	0.625
LIG_SH3_3	13	19	PF00018	0.586
LIG_SH3_3	197	203	PF00018	0.635
LIG_SH3_3	315	321	PF00018	0.564
LIG_SH3_3	55	61	PF00018	0.626
LIG_SH3_3	75	81	PF00018	0.495
MOD_CDK_SPxK_1	314	320	PF00069	0.563
MOD_CDK_SPxK_1	68	74	PF00069	0.603
MOD_CK1_1	109	115	PF00069	0.619
MOD_CK1_1	12	18	PF00069	0.582
MOD_CK1_1	251	257	PF00069	0.548
MOD_GlcNHglycan	250	253	PF01048	0.550
MOD_GlcNHglycan	289	292	PF01048	0.455
MOD_GSK3_1	103	110	PF00069	0.622
MOD_GSK3_1	8	15	PF00069	0.582
MOD_NEK2_1	313	318	PF00069	0.551
MOD_PIKK_1	251	257	PF00454	0.548
MOD_PKA_2	100	106	PF00069	0.619
MOD_PKA_2	107	113	PF00069	0.585
MOD_PKA_2	243	249	PF00069	0.547
MOD_PKA_2	272	278	PF00069	0.460
MOD_PKA_2	287	293	PF00069	0.394
MOD_PKA_2	303	309	PF00069	0.384
MOD_ProDKin_1	12	18	PF00069	0.582
MOD_ProDKin_1	314	320	PF00069	0.563
MOD_ProDKin_1	68	74	PF00069	0.603
TRG_DiLeu_BaLyEn_6	295	300	PF01217	0.452
TRG_ER_diArg_1	243	245	PF00400	0.554

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IIC2	Leishmania donovani	98%	100%