LeishMANIAdb
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Putative uracil phosphoribosyltransferase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative uracil phosphoribosyltransferase
Gene product:
uracil phosphoribosyltransferase - putative
Species:
Leishmania infantum
UniProt:
A4I9Q8_LEIIN
TriTrypDb:
LINF_340016700
Length:
242

Annotations

Annotations by Jardim et al.

Pyrimidine metabolism, uracil phosphoribosyltransferase

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 4
Pissara et al. yes yes: 20
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I9Q8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I9Q8

Function

Could not find GO biological_process term for this entry.
Molecular functions
TermNameLevelCount
GO:0003824 catalytic activity 1 12
GO:0004845 uracil phosphoribosyltransferase activity 5 7
GO:0016740 transferase activity 2 12
GO:0016757 glycosyltransferase activity 3 12
GO:0016763 pentosyltransferase activity 4 7
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 153 155 PF00675 0.360
CLV_NRD_NRD_1 198 200 PF00675 0.305
CLV_PCSK_KEX2_1 153 155 PF00082 0.360
CLV_PCSK_SKI1_1 153 157 PF00082 0.309
CLV_PCSK_SKI1_1 223 227 PF00082 0.333
CLV_PCSK_SKI1_1 61 65 PF00082 0.396
DEG_APCC_DBOX_1 222 230 PF00400 0.210
DOC_CKS1_1 30 35 PF01111 0.411
DOC_CKS1_1 78 83 PF01111 0.267
DOC_CYCLIN_yCln2_LP_2 157 163 PF00134 0.267
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PB54 Leptomonas seymouri 84% 97%
A0A0S4JQZ2 Bodo saltans 60% 100%
A0A1X0P9B6 Trypanosomatidae 64% 100%
A0A3R7M7N4 Trypanosoma rangeli 64% 100%
A0ALM3 Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / CIP 8149 / NCTC 11857 / SLCC 5334 / V8) 32% 100%
A0JSM6 Arthrobacter sp. (strain FB24) 31% 100%
A0Q306 Clostridium novyi (strain NT) 33% 100%
A0RLA2 Bacillus thuringiensis (strain Al Hakam) 33% 100%
A0RR59 Campylobacter fetus subsp. fetus (strain 82-40) 37% 100%
A0ZZM2 Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a) 32% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS