Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I9Q0_LEIIN

TriTrypDb:

LINF_340015100

Length:

107

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I9Q0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I9Q0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	101	103	PF00675	0.467
CLV_PCSK_SKI1_1	72	76	PF00082	0.553
DOC_MAPK_gen_1	71	77	PF00069	0.499
DOC_WW_Pin1_4	49	54	PF00397	0.551
LIG_BRCT_BRCA1_1	15	19	PF00533	0.472
LIG_BRCT_BRCA1_2	15	21	PF00533	0.507
LIG_FHA_2	50	56	PF00498	0.461
LIG_LIR_Gen_1	60	70	PF02991	0.355
LIG_LIR_Gen_1	73	81	PF02991	0.368
LIG_LIR_Gen_1	87	97	PF02991	0.333
LIG_LIR_Nem_3	16	22	PF02991	0.464
LIG_LIR_Nem_3	60	65	PF02991	0.363
LIG_LIR_Nem_3	73	77	PF02991	0.367
LIG_LIR_Nem_3	78	84	PF02991	0.376
LIG_SH2_SRC	22	25	PF00017	0.397
LIG_TRAF2_1	52	55	PF00917	0.534
LIG_TRFH_1	49	53	PF08558	0.569
MOD_CDK_SPxxK_3	49	56	PF00069	0.551
MOD_CK2_1	49	55	PF00069	0.475
MOD_CK2_1	76	82	PF00069	0.503
MOD_NEK2_1	1	6	PF00069	0.618
MOD_NEK2_1	75	80	PF00069	0.474
MOD_NMyristoyl	1	7	PF02799	0.491
MOD_Plk_4	76	82	PF00069	0.529
MOD_ProDKin_1	49	55	PF00069	0.540
MOD_SUMO_for_1	70	73	PF00179	0.449
TRG_DiLeu_BaEn_4	60	66	PF01217	0.363
TRG_ENDOCYTIC_2	66	69	PF00928	0.391
TRG_ENDOCYTIC_2	89	92	PF00928	0.470
TRG_ER_diArg_1	26	29	PF00400	0.419

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4J0J3	Bodo saltans	46%	100%
A0A1X0P995	Trypanosomatidae	58%	100%
A0A3S7X7N4	Leishmania donovani	100%	100%
A0A422N277	Trypanosoma rangeli	58%	100%
A4HAK9	Leishmania braziliensis	92%	100%
C6K3V4	Leptomonas seymouri	79%	100%
C9ZMY9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	54%	98%
E9B4R4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	100%	100%
Q4Q3B2	Leishmania major	99%	100%