LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I9P9_LEIIN
TriTrypDb:
LINF_340015000
Length:
691

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I9P9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I9P9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 319 323 PF00656 0.606
CLV_C14_Caspase3-7 607 611 PF00656 0.570
CLV_C14_Caspase3-7 633 637 PF00656 0.554
CLV_NRD_NRD_1 205 207 PF00675 0.560
CLV_NRD_NRD_1 238 240 PF00675 0.739
CLV_NRD_NRD_1 274 276 PF00675 0.570
CLV_NRD_NRD_1 277 279 PF00675 0.580
CLV_NRD_NRD_1 304 306 PF00675 0.662
CLV_NRD_NRD_1 313 315 PF00675 0.657
CLV_NRD_NRD_1 324 326 PF00675 0.623
CLV_NRD_NRD_1 33 35 PF00675 0.543
CLV_NRD_NRD_1 397 399 PF00675 0.590
CLV_NRD_NRD_1 416 418 PF00675 0.629
CLV_NRD_NRD_1 468 470 PF00675 0.525
CLV_NRD_NRD_1 628 630 PF00675 0.674
CLV_PCSK_FUR_1 236 240 PF00082 0.578
CLV_PCSK_FUR_1 275 279 PF00082 0.591
CLV_PCSK_KEX2_1 108 110 PF00082 0.422
CLV_PCSK_KEX2_1 205 207 PF00082 0.560
CLV_PCSK_KEX2_1 238 240 PF00082 0.679
CLV_PCSK_KEX2_1 274 276 PF00082 0.570
CLV_PCSK_KEX2_1 277 279 PF00082 0.580
CLV_PCSK_KEX2_1 303 305 PF00082 0.664
CLV_PCSK_KEX2_1 313 315 PF00082 0.653
CLV_PCSK_KEX2_1 324 326 PF00082 0.619
CLV_PCSK_KEX2_1 33 35 PF00082 0.543
CLV_PCSK_KEX2_1 397 399 PF00082 0.590
CLV_PCSK_KEX2_1 416 418 PF00082 0.629
CLV_PCSK_KEX2_1 468 470 PF00082 0.525
CLV_PCSK_KEX2_1 627 629 PF00082 0.688
CLV_PCSK_PC1ET2_1 108 110 PF00082 0.422
CLV_PCSK_SKI1_1 108 112 PF00082 0.421
CLV_PCSK_SKI1_1 241 245 PF00082 0.663
CLV_PCSK_SKI1_1 85 89 PF00082 0.419
CLV_Separin_Metazoa 23 27 PF03568 0.503
DEG_APCC_DBOX_1 154 162 PF00400 0.580
DEG_APCC_DBOX_1 467 475 PF00400 0.534
DEG_SPOP_SBC_1 175 179 PF00917 0.684
DEG_SPOP_SBC_1 210 214 PF00917 0.713
DEG_SPOP_SBC_1 222 226 PF00917 0.569
DEG_SPOP_SBC_1 242 246 PF00917 0.519
DEG_SPOP_SBC_1 504 508 PF00917 0.551
DOC_ANK_TNKS_1 335 342 PF00023 0.644
DOC_CYCLIN_RxL_1 105 114 PF00134 0.482
DOC_CYCLIN_RxL_1 155 164 PF00134 0.533
DOC_CYCLIN_yCln2_LP_2 659 665 PF00134 0.385
DOC_MAPK_gen_1 33 42 PF00069 0.546
DOC_MIT_MIM_1 104 113 PF04212 0.480
DOC_PP1_RVXF_1 395 402 PF00149 0.584
DOC_PP1_RVXF_1 488 494 PF00149 0.523
DOC_PP2B_LxvP_1 659 662 PF13499 0.379
DOC_PP4_FxxP_1 353 356 PF00568 0.684
DOC_USP7_MATH_1 166 170 PF00917 0.618
DOC_USP7_MATH_1 181 185 PF00917 0.531
DOC_USP7_MATH_1 210 214 PF00917 0.685
DOC_USP7_MATH_1 222 226 PF00917 0.569
DOC_USP7_MATH_1 243 247 PF00917 0.690
DOC_USP7_MATH_1 262 266 PF00917 0.491
DOC_USP7_MATH_1 386 390 PF00917 0.672
DOC_USP7_MATH_1 504 508 PF00917 0.551
DOC_USP7_MATH_1 528 532 PF00917 0.641
DOC_WW_Pin1_4 218 223 PF00397 0.613
DOC_WW_Pin1_4 248 253 PF00397 0.672
DOC_WW_Pin1_4 260 265 PF00397 0.529
DOC_WW_Pin1_4 307 312 PF00397 0.645
DOC_WW_Pin1_4 360 365 PF00397 0.675
DOC_WW_Pin1_4 437 442 PF00397 0.706
DOC_WW_Pin1_4 577 582 PF00397 0.572
DOC_WW_Pin1_4 612 617 PF00397 0.626
DOC_WW_Pin1_4 621 626 PF00397 0.519
LIG_14-3-3_CanoR_1 176 181 PF00244 0.537
LIG_14-3-3_CanoR_1 241 250 PF00244 0.655
LIG_Actin_WH2_2 549 567 PF00022 0.481
LIG_BRCT_BRCA1_1 128 132 PF00533 0.477
LIG_Clathr_ClatBox_1 110 114 PF01394 0.484
LIG_deltaCOP1_diTrp_1 456 464 PF00928 0.501
LIG_EVH1_2 349 353 PF00568 0.585
LIG_FHA_1 214 220 PF00498 0.635
LIG_FHA_1 495 501 PF00498 0.433
LIG_FHA_1 506 512 PF00498 0.412
LIG_FHA_1 567 573 PF00498 0.694
LIG_FHA_1 650 656 PF00498 0.590
LIG_FHA_1 675 681 PF00498 0.532
LIG_FHA_1 76 82 PF00498 0.477
LIG_FHA_2 186 192 PF00498 0.563
LIG_FHA_2 317 323 PF00498 0.565
LIG_FHA_2 677 683 PF00498 0.547
LIG_LIR_Gen_1 164 175 PF02991 0.511
LIG_LIR_Gen_1 2 11 PF02991 0.600
LIG_LIR_Gen_1 36 47 PF02991 0.486
LIG_LIR_Gen_1 682 691 PF02991 0.410
LIG_LIR_Nem_3 104 110 PF02991 0.480
LIG_LIR_Nem_3 164 170 PF02991 0.503
LIG_LIR_Nem_3 2 7 PF02991 0.586
LIG_LIR_Nem_3 36 42 PF02991 0.506
LIG_LIR_Nem_3 455 461 PF02991 0.518
LIG_LIR_Nem_3 682 687 PF02991 0.404
LIG_PDZ_Class_2 686 691 PF00595 0.409
LIG_SH2_CRK 167 171 PF00017 0.514
LIG_SH2_CRK 77 81 PF00017 0.478
LIG_SH2_STAP1 167 171 PF00017 0.584
LIG_SH2_STAP1 60 64 PF00017 0.454
LIG_SH2_STAP1 77 81 PF00017 0.347
LIG_SH2_STAT5 574 577 PF00017 0.592
LIG_SH2_STAT5 605 608 PF00017 0.636
LIG_SH2_STAT5 77 80 PF00017 0.475
LIG_SH3_2 349 354 PF14604 0.589
LIG_SH3_3 346 352 PF00018 0.690
LIG_SH3_3 358 364 PF00018 0.611
LIG_SH3_3 438 444 PF00018 0.592
LIG_SH3_3 498 504 PF00018 0.440
LIG_SUMO_SIM_par_1 78 84 PF11976 0.476
LIG_TRAF2_1 477 480 PF00917 0.624
LIG_ULM_U2AF65_1 397 402 PF00076 0.579
LIG_WRC_WIRS_1 1 6 PF05994 0.606
MOD_CDC14_SPxK_1 310 313 PF00782 0.633
MOD_CDC14_SPxK_1 624 627 PF00782 0.663
MOD_CDK_SPK_2 248 253 PF00069 0.643
MOD_CDK_SPxK_1 307 313 PF00069 0.629
MOD_CDK_SPxK_1 621 627 PF00069 0.673
MOD_CDK_SPxxK_3 307 314 PF00069 0.650
MOD_CDK_SPxxK_3 621 628 PF00069 0.629
MOD_CK1_1 179 185 PF00069 0.604
MOD_CK1_1 209 215 PF00069 0.714
MOD_CK1_1 217 223 PF00069 0.619
MOD_CK1_1 225 231 PF00069 0.684
MOD_CK1_1 246 252 PF00069 0.565
MOD_CK1_1 263 269 PF00069 0.529
MOD_CK1_1 3 9 PF00069 0.605
MOD_CK1_1 316 322 PF00069 0.805
MOD_CK1_1 362 368 PF00069 0.737
MOD_CK1_1 374 380 PF00069 0.584
MOD_CK1_1 409 415 PF00069 0.629
MOD_CK1_1 437 443 PF00069 0.697
MOD_CK1_1 460 466 PF00069 0.448
MOD_CK1_1 483 489 PF00069 0.585
MOD_CK1_1 499 505 PF00069 0.378
MOD_CK1_1 531 537 PF00069 0.581
MOD_CK1_1 577 583 PF00069 0.511
MOD_CK1_1 595 601 PF00069 0.718
MOD_CK2_1 577 583 PF00069 0.593
MOD_CK2_1 676 682 PF00069 0.565
MOD_CMANNOS 493 496 PF00535 0.564
MOD_Cter_Amidation 322 325 PF01082 0.636
MOD_Cter_Amidation 395 398 PF01082 0.595
MOD_GlcNHglycan 184 187 PF01048 0.566
MOD_GlcNHglycan 208 211 PF01048 0.713
MOD_GlcNHglycan 245 248 PF01048 0.688
MOD_GlcNHglycan 306 310 PF01048 0.634
MOD_GlcNHglycan 373 376 PF01048 0.689
MOD_GlcNHglycan 380 383 PF01048 0.689
MOD_GlcNHglycan 394 397 PF01048 0.526
MOD_GlcNHglycan 436 439 PF01048 0.680
MOD_GlcNHglycan 485 488 PF01048 0.615
MOD_GlcNHglycan 528 531 PF01048 0.637
MOD_GlcNHglycan 533 536 PF01048 0.616
MOD_GlcNHglycan 547 550 PF01048 0.420
MOD_GlcNHglycan 600 603 PF01048 0.592
MOD_GlcNHglycan 606 609 PF01048 0.550
MOD_GSK3_1 161 168 PF00069 0.608
MOD_GSK3_1 175 182 PF00069 0.502
MOD_GSK3_1 206 213 PF00069 0.712
MOD_GSK3_1 214 221 PF00069 0.623
MOD_GSK3_1 222 229 PF00069 0.565
MOD_GSK3_1 242 249 PF00069 0.544
MOD_GSK3_1 256 263 PF00069 0.574
MOD_GSK3_1 305 312 PF00069 0.687
MOD_GSK3_1 313 320 PF00069 0.627
MOD_GSK3_1 370 377 PF00069 0.669
MOD_GSK3_1 406 413 PF00069 0.601
MOD_GSK3_1 495 502 PF00069 0.518
MOD_GSK3_1 588 595 PF00069 0.579
MOD_GSK3_1 617 624 PF00069 0.675
MOD_GSK3_1 649 656 PF00069 0.597
MOD_LATS_1 174 180 PF00433 0.628
MOD_N-GLC_1 182 187 PF02516 0.688
MOD_N-GLC_2 604 606 PF02516 0.669
MOD_NEK2_1 161 166 PF00069 0.570
MOD_NEK2_1 283 288 PF00069 0.531
MOD_NEK2_1 494 499 PF00069 0.619
MOD_NEK2_1 53 58 PF00069 0.472
MOD_NEK2_1 572 577 PF00069 0.579
MOD_NEK2_1 674 679 PF00069 0.491
MOD_NEK2_2 166 171 PF00069 0.512
MOD_PIKK_1 200 206 PF00454 0.655
MOD_PIKK_1 263 269 PF00454 0.544
MOD_PIKK_1 635 641 PF00454 0.631
MOD_PK_1 176 182 PF00069 0.631
MOD_PK_1 538 544 PF00069 0.549
MOD_PKA_1 313 319 PF00069 0.667
MOD_PKA_2 126 132 PF00069 0.511
MOD_PKA_2 175 181 PF00069 0.570
MOD_PKA_2 313 319 PF00069 0.669
MOD_PKA_2 483 489 PF00069 0.574
MOD_PKA_2 595 601 PF00069 0.620
MOD_PKB_1 239 247 PF00069 0.732
MOD_PKB_1 303 311 PF00069 0.630
MOD_PKB_1 592 600 PF00069 0.615
MOD_Plk_1 182 188 PF00069 0.687
MOD_Plk_1 35 41 PF00069 0.555
MOD_Plk_1 504 510 PF00069 0.503
MOD_Plk_4 166 172 PF00069 0.513
MOD_Plk_4 35 41 PF00069 0.597
MOD_Plk_4 496 502 PF00069 0.482
MOD_Plk_4 505 511 PF00069 0.450
MOD_Plk_4 76 82 PF00069 0.473
MOD_ProDKin_1 218 224 PF00069 0.612
MOD_ProDKin_1 248 254 PF00069 0.674
MOD_ProDKin_1 260 266 PF00069 0.524
MOD_ProDKin_1 307 313 PF00069 0.648
MOD_ProDKin_1 360 366 PF00069 0.678
MOD_ProDKin_1 437 443 PF00069 0.698
MOD_ProDKin_1 577 583 PF00069 0.574
MOD_ProDKin_1 612 618 PF00069 0.629
MOD_ProDKin_1 621 627 PF00069 0.520
MOD_SUMO_for_1 87 90 PF00179 0.417
TRG_DiLeu_BaEn_4 101 107 PF01217 0.418
TRG_DiLeu_BaEn_4 89 95 PF01217 0.432
TRG_DiLeu_BaLyEn_6 106 111 PF01217 0.485
TRG_ENDOCYTIC_2 167 170 PF00928 0.513
TRG_ENDOCYTIC_2 77 80 PF00928 0.475
TRG_ER_diArg_1 236 239 PF00400 0.721
TRG_ER_diArg_1 273 275 PF00400 0.579
TRG_ER_diArg_1 276 278 PF00400 0.576
TRG_ER_diArg_1 302 305 PF00400 0.664
TRG_ER_diArg_1 313 315 PF00400 0.580
TRG_ER_diArg_1 397 400 PF00400 0.583
TRG_ER_diArg_1 627 629 PF00400 0.688
TRG_ER_diArg_1 640 643 PF00400 0.506
TRG_ER_diArg_1 669 672 PF00400 0.436
TRG_Pf-PMV_PEXEL_1 109 114 PF00026 0.423
TRG_Pf-PMV_PEXEL_1 274 279 PF00026 0.439
TRG_Pf-PMV_PEXEL_1 426 430 PF00026 0.662
TRG_Pf-PMV_PEXEL_1 469 473 PF00026 0.622

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IE77 Leishmania donovani 100% 100%
A4HAK8 Leishmania braziliensis 68% 100%
C6K3V3 Leptomonas seymouri 38% 100%
E9B4R3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 99%
Q4Q3B3 Leishmania major 90% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS