Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I9N6_LEIIN

TriTrypDb:

LINF_340012200

Length:

927

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I9N6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I9N6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	149	153	PF00656	0.766
CLV_C14_Caspase3-7	315	319	PF00656	0.444
CLV_NRD_NRD_1	256	258	PF00675	0.594
CLV_NRD_NRD_1	278	280	PF00675	0.620
CLV_NRD_NRD_1	378	380	PF00675	0.683
CLV_NRD_NRD_1	578	580	PF00675	0.706
CLV_NRD_NRD_1	630	632	PF00675	0.623
CLV_NRD_NRD_1	655	657	PF00675	0.636
CLV_NRD_NRD_1	664	666	PF00675	0.527
CLV_NRD_NRD_1	671	673	PF00675	0.508
CLV_NRD_NRD_1	706	708	PF00675	0.534
CLV_NRD_NRD_1	714	716	PF00675	0.571
CLV_NRD_NRD_1	775	777	PF00675	0.835
CLV_NRD_NRD_1	887	889	PF00675	0.760
CLV_PCSK_FUR_1	576	580	PF00082	0.627
CLV_PCSK_FUR_1	662	666	PF00082	0.615
CLV_PCSK_FUR_1	667	671	PF00082	0.604
CLV_PCSK_KEX2_1	247	249	PF00082	0.576
CLV_PCSK_KEX2_1	278	280	PF00082	0.620
CLV_PCSK_KEX2_1	378	380	PF00082	0.683
CLV_PCSK_KEX2_1	48	50	PF00082	0.721
CLV_PCSK_KEX2_1	578	580	PF00082	0.704
CLV_PCSK_KEX2_1	654	656	PF00082	0.642
CLV_PCSK_KEX2_1	664	666	PF00082	0.542
CLV_PCSK_KEX2_1	667	669	PF00082	0.540
CLV_PCSK_KEX2_1	670	672	PF00082	0.538
CLV_PCSK_KEX2_1	713	715	PF00082	0.588
CLV_PCSK_KEX2_1	723	725	PF00082	0.580
CLV_PCSK_KEX2_1	836	838	PF00082	0.730
CLV_PCSK_PC1ET2_1	247	249	PF00082	0.576
CLV_PCSK_PC1ET2_1	48	50	PF00082	0.721
CLV_PCSK_PC1ET2_1	723	725	PF00082	0.673
CLV_PCSK_PC1ET2_1	836	838	PF00082	0.730
CLV_PCSK_PC7_1	664	670	PF00082	0.609
CLV_PCSK_SKI1_1	186	190	PF00082	0.716
CLV_PCSK_SKI1_1	203	207	PF00082	0.483
CLV_PCSK_SKI1_1	266	270	PF00082	0.590
CLV_PCSK_SKI1_1	539	543	PF00082	0.752
CLV_PCSK_SKI1_1	776	780	PF00082	0.720
CLV_PCSK_SKI1_1	807	811	PF00082	0.760
CLV_PCSK_SKI1_1	81	85	PF00082	0.755
CLV_PCSK_SKI1_1	830	834	PF00082	0.723
CLV_PCSK_SKI1_1	849	853	PF00082	0.437
CLV_PCSK_SKI1_1	857	861	PF00082	0.678
CLV_PCSK_SKI1_1	877	881	PF00082	0.502
CLV_PCSK_SKI1_1	900	904	PF00082	0.731
DEG_APCC_DBOX_1	671	679	PF00400	0.649
DEG_COP1_1	739	749	PF00400	0.623
DEG_SCF_FBW7_2	194	200	PF00400	0.609
DEG_SPOP_SBC_1	590	594	PF00917	0.716
DOC_CKS1_1	194	199	PF01111	0.598
DOC_CKS1_1	37	42	PF01111	0.812
DOC_CKS1_1	502	507	PF01111	0.651
DOC_CYCLIN_RxL_1	667	681	PF00134	0.625
DOC_CYCLIN_RxL_1	773	782	PF00134	0.821
DOC_CYCLIN_yCln2_LP_2	191	197	PF00134	0.580
DOC_MAPK_DCC_7	836	844	PF00069	0.633
DOC_MAPK_gen_1	576	584	PF00069	0.620
DOC_MAPK_gen_1	667	679	PF00069	0.637
DOC_MAPK_gen_1	825	833	PF00069	0.602
DOC_MAPK_gen_1	836	844	PF00069	0.632
DOC_MAPK_MEF2A_6	18	26	PF00069	0.685
DOC_MAPK_MEF2A_6	670	679	PF00069	0.614
DOC_MAPK_MEF2A_6	825	833	PF00069	0.602
DOC_MAPK_MEF2A_6	836	844	PF00069	0.632
DOC_MAPK_MEF2A_6	900	908	PF00069	0.615
DOC_MAPK_NFAT4_5	672	680	PF00069	0.654
DOC_PP1_RVXF_1	828	834	PF00149	0.703
DOC_PP2B_LxvP_1	191	194	PF13499	0.587
DOC_PP4_FxxP_1	280	283	PF00568	0.656
DOC_PP4_FxxP_1	561	564	PF00568	0.636
DOC_PP4_FxxP_1	851	854	PF00568	0.650
DOC_USP7_MATH_1	10	14	PF00917	0.733
DOC_USP7_MATH_1	362	366	PF00917	0.694
DOC_USP7_MATH_1	368	372	PF00917	0.632
DOC_USP7_MATH_1	517	521	PF00917	0.765
DOC_USP7_MATH_1	522	526	PF00917	0.804
DOC_USP7_MATH_1	60	64	PF00917	0.750
DOC_USP7_MATH_1	600	604	PF00917	0.763
DOC_USP7_MATH_1	65	69	PF00917	0.775
DOC_USP7_MATH_1	74	78	PF00917	0.612
DOC_USP7_MATH_1	745	749	PF00917	0.765
DOC_USP7_MATH_1	791	795	PF00917	0.781
DOC_USP7_MATH_1	881	885	PF00917	0.793
DOC_USP7_MATH_1	887	891	PF00917	0.772
DOC_WW_Pin1_4	103	108	PF00397	0.733
DOC_WW_Pin1_4	123	128	PF00397	0.602
DOC_WW_Pin1_4	133	138	PF00397	0.766
DOC_WW_Pin1_4	141	146	PF00397	0.814
DOC_WW_Pin1_4	193	198	PF00397	0.609
DOC_WW_Pin1_4	232	237	PF00397	0.553
DOC_WW_Pin1_4	308	313	PF00397	0.573
DOC_WW_Pin1_4	354	359	PF00397	0.700
DOC_WW_Pin1_4	36	41	PF00397	0.817
DOC_WW_Pin1_4	371	376	PF00397	0.576
DOC_WW_Pin1_4	501	506	PF00397	0.741
DOC_WW_Pin1_4	560	565	PF00397	0.811
DOC_WW_Pin1_4	607	612	PF00397	0.714
DOC_WW_Pin1_4	63	68	PF00397	0.737
DOC_WW_Pin1_4	802	807	PF00397	0.810
DOC_WW_Pin1_4	818	823	PF00397	0.746
LIG_14-3-3_CanoR_1	108	114	PF00244	0.815
LIG_14-3-3_CanoR_1	158	167	PF00244	0.638
LIG_14-3-3_CanoR_1	403	407	PF00244	0.751
LIG_14-3-3_CanoR_1	556	562	PF00244	0.749
LIG_14-3-3_CanoR_1	578	583	PF00244	0.829
LIG_14-3-3_CanoR_1	596	602	PF00244	0.730
LIG_14-3-3_CanoR_1	793	802	PF00244	0.802
LIG_14-3-3_CanoR_1	804	810	PF00244	0.679
LIG_14-3-3_CanoR_1	849	854	PF00244	0.624
LIG_APCC_ABBA_1	829	834	PF00400	0.710
LIG_APCC_ABBAyCdc20_2	828	834	PF00400	0.711
LIG_BIR_III_2	599	603	PF00653	0.744
LIG_BRCT_BRCA1_1	111	115	PF00533	0.718
LIG_BRCT_BRCA1_1	143	147	PF00533	0.788
LIG_BRCT_BRCA1_1	234	238	PF00533	0.641
LIG_BRCT_BRCA1_1	276	280	PF00533	0.664
LIG_BRCT_BRCA1_1	427	431	PF00533	0.585
LIG_BRCT_BRCA1_1	683	687	PF00533	0.504
LIG_deltaCOP1_diTrp_1	289	297	PF00928	0.506
LIG_deltaCOP1_diTrp_1	919	925	PF00928	0.616
LIG_DLG_GKlike_1	894	902	PF00625	0.550
LIG_eIF4E_1	425	431	PF01652	0.570
LIG_FHA_1	25	31	PF00498	0.825
LIG_FHA_1	303	309	PF00498	0.584
LIG_FHA_1	379	385	PF00498	0.703
LIG_FHA_1	390	396	PF00498	0.595
LIG_FHA_1	469	475	PF00498	0.615
LIG_FHA_1	498	504	PF00498	0.731
LIG_FHA_1	579	585	PF00498	0.642
LIG_FHA_1	865	871	PF00498	0.735
LIG_FHA_1	93	99	PF00498	0.770
LIG_FHA_2	239	245	PF00498	0.582
LIG_FHA_2	267	273	PF00498	0.646
LIG_FHA_2	380	386	PF00498	0.760
LIG_FHA_2	502	508	PF00498	0.729
LIG_FHA_2	56	62	PF00498	0.836
LIG_FHA_2	755	761	PF00498	0.743
LIG_FHA_2	858	864	PF00498	0.805
LIG_IRF3_LxIS_1	605	610	PF10401	0.766
LIG_LIR_Apic_2	277	283	PF02991	0.571
LIG_LIR_Apic_2	560	564	PF02991	0.634
LIG_LIR_Apic_2	786	791	PF02991	0.672
LIG_LIR_Gen_1	112	117	PF02991	0.730
LIG_LIR_Gen_1	289	297	PF02991	0.506
LIG_LIR_Gen_1	440	451	PF02991	0.499
LIG_LIR_Gen_1	684	694	PF02991	0.674
LIG_LIR_Nem_3	112	116	PF02991	0.731
LIG_LIR_Nem_3	289	293	PF02991	0.521
LIG_LIR_Nem_3	325	329	PF02991	0.509
LIG_LIR_Nem_3	440	446	PF02991	0.504
LIG_LIR_Nem_3	456	460	PF02991	0.642
LIG_LIR_Nem_3	684	690	PF02991	0.605
LIG_LYPXL_SIV_4	312	320	PF13949	0.504
LIG_PAM2_1	281	293	PF00658	0.507
LIG_PTAP_UEV_1	882	887	PF05743	0.610
LIG_PTB_Apo_2	842	849	PF02174	0.616
LIG_REV1ctd_RIR_1	830	839	PF16727	0.723
LIG_SH2_CRK	113	117	PF00017	0.701
LIG_SH2_CRK	213	217	PF00017	0.456
LIG_SH2_CRK	462	466	PF00017	0.611
LIG_SH2_SRC	788	791	PF00017	0.787
LIG_SH2_STAT5	292	295	PF00017	0.511
LIG_SH2_STAT5	326	329	PF00017	0.530
LIG_SH2_STAT5	788	791	PF00017	0.685
LIG_SH3_2	883	888	PF14604	0.649
LIG_SH3_3	104	110	PF00018	0.732
LIG_SH3_3	13	19	PF00018	0.775
LIG_SH3_3	142	148	PF00018	0.831
LIG_SH3_3	191	197	PF00018	0.653
LIG_SH3_3	34	40	PF00018	0.770
LIG_SH3_3	407	413	PF00018	0.662
LIG_SH3_3	429	435	PF00018	0.572
LIG_SH3_3	59	65	PF00018	0.763
LIG_SH3_3	613	619	PF00018	0.725
LIG_SH3_3	67	73	PF00018	0.667
LIG_SH3_3	676	682	PF00018	0.681
LIG_SH3_3	758	764	PF00018	0.729
LIG_SH3_3	880	886	PF00018	0.728
LIG_SUMO_SIM_anti_2	901	907	PF11976	0.594
LIG_SUMO_SIM_par_1	304	311	PF11976	0.613
LIG_SUMO_SIM_par_1	412	418	PF11976	0.647
LIG_SUMO_SIM_par_1	675	681	PF11976	0.685
LIG_TRAF2_1	197	200	PF00917	0.619
LIG_TRAF2_1	509	512	PF00917	0.762
LIG_TRAF2_1	622	625	PF00917	0.721
MOD_CDK_SPK_2	103	108	PF00069	0.733
MOD_CDK_SPK_2	802	807	PF00069	0.725
MOD_CDK_SPxxK_3	371	378	PF00069	0.599
MOD_CDK_SPxxK_3	818	825	PF00069	0.681
MOD_CK1_1	119	125	PF00069	0.725
MOD_CK1_1	126	132	PF00069	0.748
MOD_CK1_1	150	156	PF00069	0.828
MOD_CK1_1	371	377	PF00069	0.765
MOD_CK1_1	389	395	PF00069	0.553
MOD_CK1_1	453	459	PF00069	0.543
MOD_CK1_1	520	526	PF00069	0.833
MOD_CK1_1	544	550	PF00069	0.711
MOD_CK1_1	560	566	PF00069	0.790
MOD_CK1_1	591	597	PF00069	0.715
MOD_CK1_1	603	609	PF00069	0.749
MOD_CK1_1	610	616	PF00069	0.691
MOD_CK1_1	620	626	PF00069	0.683
MOD_CK1_1	63	69	PF00069	0.787
MOD_CK1_1	739	745	PF00069	0.702
MOD_CK1_1	805	811	PF00069	0.751
MOD_CK2_1	238	244	PF00069	0.577
MOD_CK2_1	266	272	PF00069	0.648
MOD_CK2_1	322	328	PF00069	0.509
MOD_CK2_1	374	380	PF00069	0.728
MOD_CK2_1	506	512	PF00069	0.690
MOD_CK2_1	811	817	PF00069	0.747
MOD_CMANNOS	922	925	PF00535	0.623
MOD_GlcNHglycan	103	106	PF01048	0.811
MOD_GlcNHglycan	12	15	PF01048	0.749
MOD_GlcNHglycan	155	158	PF01048	0.764
MOD_GlcNHglycan	162	165	PF01048	0.776
MOD_GlcNHglycan	388	391	PF01048	0.589
MOD_GlcNHglycan	41	44	PF01048	0.814
MOD_GlcNHglycan	417	420	PF01048	0.635
MOD_GlcNHglycan	443	446	PF01048	0.560
MOD_GlcNHglycan	517	520	PF01048	0.754
MOD_GlcNHglycan	522	525	PF01048	0.711
MOD_GlcNHglycan	570	573	PF01048	0.846
MOD_GlcNHglycan	636	639	PF01048	0.588
MOD_GlcNHglycan	67	70	PF01048	0.715
MOD_GlcNHglycan	730	733	PF01048	0.770
MOD_GlcNHglycan	747	750	PF01048	0.531
MOD_GlcNHglycan	784	788	PF01048	0.662
MOD_GlcNHglycan	793	796	PF01048	0.715
MOD_GlcNHglycan	883	886	PF01048	0.782
MOD_GlcNHglycan	889	892	PF01048	0.764
MOD_GSK3_1	119	126	PF00069	0.639
MOD_GSK3_1	146	153	PF00069	0.754
MOD_GSK3_1	156	163	PF00069	0.721
MOD_GSK3_1	262	269	PF00069	0.570
MOD_GSK3_1	354	361	PF00069	0.728
MOD_GSK3_1	370	377	PF00069	0.578
MOD_GSK3_1	497	504	PF00069	0.710
MOD_GSK3_1	5	12	PF00069	0.726
MOD_GSK3_1	50	57	PF00069	0.707
MOD_GSK3_1	513	520	PF00069	0.622
MOD_GSK3_1	540	547	PF00069	0.718
MOD_GSK3_1	588	595	PF00069	0.716
MOD_GSK3_1	603	610	PF00069	0.756
MOD_GSK3_1	728	735	PF00069	0.697
MOD_GSK3_1	736	743	PF00069	0.699
MOD_GSK3_1	789	796	PF00069	0.789
MOD_GSK3_1	805	812	PF00069	0.601
MOD_GSK3_1	859	866	PF00069	0.726
MOD_GSK3_1	877	884	PF00069	0.689
MOD_GSK3_1	894	901	PF00069	0.623
MOD_N-GLC_1	369	374	PF02516	0.776
MOD_N-GLC_1	5	10	PF02516	0.709
MOD_N-GLC_1	568	573	PF02516	0.762
MOD_N-GLC_1	588	593	PF02516	0.738
MOD_N-GLC_1	607	612	PF02516	0.752
MOD_NEK2_1	262	267	PF00069	0.577
MOD_NEK2_1	388	393	PF00069	0.593
MOD_NEK2_1	402	407	PF00069	0.755
MOD_NEK2_1	415	420	PF00069	0.549
MOD_NEK2_1	545	550	PF00069	0.689
MOD_NEK2_1	809	814	PF00069	0.825
MOD_NEK2_1	898	903	PF00069	0.531
MOD_NEK2_1	9	14	PF00069	0.770
MOD_NEK2_2	74	79	PF00069	0.630
MOD_PIKK_1	331	337	PF00454	0.559
MOD_PIKK_1	450	456	PF00454	0.513
MOD_PK_1	816	822	PF00069	0.718
MOD_PKA_1	378	384	PF00069	0.705
MOD_PKA_1	578	584	PF00069	0.618
MOD_PKA_1	656	662	PF00069	0.577
MOD_PKA_2	119	125	PF00069	0.725
MOD_PKA_2	150	156	PF00069	0.742
MOD_PKA_2	157	163	PF00069	0.768
MOD_PKA_2	302	308	PF00069	0.578
MOD_PKA_2	378	384	PF00069	0.685
MOD_PKA_2	402	408	PF00069	0.752
MOD_PKA_2	578	584	PF00069	0.638
MOD_PKA_2	595	601	PF00069	0.647
MOD_PKA_2	739	745	PF00069	0.692
MOD_PKA_2	887	893	PF00069	0.766
MOD_PKB_1	576	584	PF00069	0.834
MOD_PKB_1	654	662	PF00069	0.578
MOD_Plk_1	238	244	PF00069	0.678
MOD_Plk_1	379	385	PF00069	0.670
MOD_Plk_1	5	11	PF00069	0.709
MOD_Plk_1	816	822	PF00069	0.718
MOD_Plk_1	898	904	PF00069	0.664
MOD_Plk_4	109	115	PF00069	0.714
MOD_Plk_4	302	308	PF00069	0.578
MOD_Plk_4	322	328	PF00069	0.281
MOD_Plk_4	379	385	PF00069	0.682
MOD_Plk_4	425	431	PF00069	0.592
MOD_Plk_4	453	459	PF00069	0.565
MOD_Plk_4	898	904	PF00069	0.618
MOD_ProDKin_1	103	109	PF00069	0.732
MOD_ProDKin_1	123	129	PF00069	0.605
MOD_ProDKin_1	133	139	PF00069	0.769
MOD_ProDKin_1	141	147	PF00069	0.812
MOD_ProDKin_1	193	199	PF00069	0.605
MOD_ProDKin_1	232	238	PF00069	0.555
MOD_ProDKin_1	308	314	PF00069	0.570
MOD_ProDKin_1	354	360	PF00069	0.703
MOD_ProDKin_1	36	42	PF00069	0.817
MOD_ProDKin_1	371	377	PF00069	0.573
MOD_ProDKin_1	501	507	PF00069	0.744
MOD_ProDKin_1	560	566	PF00069	0.812
MOD_ProDKin_1	607	613	PF00069	0.716
MOD_ProDKin_1	63	69	PF00069	0.737
MOD_ProDKin_1	802	808	PF00069	0.809
MOD_ProDKin_1	818	824	PF00069	0.746
MOD_SUMO_for_1	205	208	PF00179	0.568
MOD_SUMO_rev_2	428	437	PF00179	0.666
MOD_SUMO_rev_2	507	516	PF00179	0.761
MOD_SUMO_rev_2	705	710	PF00179	0.566
TRG_DiLeu_BaEn_1	899	904	PF01217	0.638
TRG_DiLeu_BaEn_2	685	691	PF01217	0.596
TRG_DiLeu_BaLyEn_6	410	415	PF01217	0.662
TRG_DiLeu_BaLyEn_6	673	678	PF01217	0.621
TRG_ENDOCYTIC_2	113	116	PF00928	0.725
TRG_ENDOCYTIC_2	213	216	PF00928	0.459
TRG_ENDOCYTIC_2	462	465	PF00928	0.619
TRG_ENDOCYTIC_2	558	561	PF00928	0.698
TRG_ER_diArg_1	117	120	PF00400	0.722
TRG_ER_diArg_1	278	280	PF00400	0.589
TRG_ER_diArg_1	576	579	PF00400	0.701
TRG_ER_diArg_1	654	656	PF00400	0.642
TRG_ER_diArg_1	662	665	PF00400	0.565
TRG_ER_diArg_1	667	670	PF00400	0.543
TRG_ER_diArg_1	694	697	PF00400	0.586
TRG_ER_diArg_1	713	715	PF00400	0.591
TRG_ER_diArg_1	827	830	PF00400	0.638
TRG_NES_CRM1_1	440	455	PF08389	0.503
TRG_Pf-PMV_PEXEL_1	776	781	PF00026	0.821

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAX6	Leptomonas seymouri	42%	77%
A0A3S7X7K4	Leishmania donovani	98%	84%
A4HAH6	Leishmania braziliensis	66%	100%
E9B4N5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%
Q4Q3E1	Leishmania major	89%	100%