LeishMANIAdb
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Ch34 protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Ch34 protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I9M3_LEIIN
TriTrypDb:
LINF_340010900
Length:
491

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) yes yes: 3
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I9M3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I9M3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 200 204 PF00656 0.617
CLV_C14_Caspase3-7 234 238 PF00656 0.484
CLV_C14_Caspase3-7 81 85 PF00656 0.719
CLV_NRD_NRD_1 457 459 PF00675 0.611
CLV_NRD_NRD_1 59 61 PF00675 0.696
CLV_PCSK_KEX2_1 457 459 PF00082 0.611
DEG_APCC_DBOX_1 258 266 PF00400 0.520
DEG_SCF_FBW7_2 21 28 PF00400 0.641
DEG_SPOP_SBC_1 161 165 PF00917 0.713
DEG_SPOP_SBC_1 205 209 PF00917 0.566
DOC_CKS1_1 22 27 PF01111 0.641
DOC_CKS1_1 242 247 PF01111 0.492
DOC_CYCLIN_RxL_1 304 314 PF00134 0.490
DOC_MAPK_MEF2A_6 134 142 PF00069 0.576
DOC_PP1_RVXF_1 360 367 PF00149 0.615
DOC_PP2B_LxvP_1 486 489 PF13499 0.579
DOC_PP4_MxPP_1 459 462 PF00568 0.625
DOC_USP7_MATH_1 146 150 PF00917 0.685
DOC_USP7_MATH_1 161 165 PF00917 0.730
DOC_USP7_MATH_1 205 209 PF00917 0.609
DOC_USP7_MATH_1 379 383 PF00917 0.643
DOC_USP7_MATH_1 410 414 PF00917 0.695
DOC_USP7_MATH_1 445 449 PF00917 0.733
DOC_USP7_MATH_1 51 55 PF00917 0.687
DOC_USP7_UBL2_3 158 162 PF12436 0.669
DOC_WW_Pin1_4 144 149 PF00397 0.784
DOC_WW_Pin1_4 162 167 PF00397 0.567
DOC_WW_Pin1_4 21 26 PF00397 0.640
DOC_WW_Pin1_4 216 221 PF00397 0.586
DOC_WW_Pin1_4 241 246 PF00397 0.604
DOC_WW_Pin1_4 260 265 PF00397 0.448
DOC_WW_Pin1_4 286 291 PF00397 0.511
DOC_WW_Pin1_4 299 304 PF00397 0.524
DOC_WW_Pin1_4 484 489 PF00397 0.620
LIG_14-3-3_CanoR_1 11 21 PF00244 0.649
LIG_14-3-3_CanoR_1 395 400 PF00244 0.656
LIG_BIR_III_2 145 149 PF00653 0.613
LIG_BIR_III_4 403 407 PF00653 0.618
LIG_FHA_1 13 19 PF00498 0.637
LIG_FHA_1 311 317 PF00498 0.564
LIG_FHA_1 367 373 PF00498 0.621
LIG_FHA_1 409 415 PF00498 0.696
LIG_FHA_1 53 59 PF00498 0.759
LIG_FHA_1 81 87 PF00498 0.671
LIG_FHA_2 22 28 PF00498 0.730
LIG_FHA_2 400 406 PF00498 0.673
LIG_FHA_2 449 455 PF00498 0.620
LIG_FHA_2 57 63 PF00498 0.754
LIG_LIR_Apic_2 208 214 PF02991 0.471
LIG_LIR_Gen_1 237 245 PF02991 0.458
LIG_LIR_Gen_1 439 445 PF02991 0.624
LIG_LIR_Nem_3 237 242 PF02991 0.459
LIG_LIR_Nem_3 304 309 PF02991 0.406
LIG_LIR_Nem_3 439 443 PF02991 0.624
LIG_MAD2 39 47 PF02301 0.639
LIG_PROFILIN_1 45 51 PF00235 0.661
LIG_SH2_CRK 211 215 PF00017 0.542
LIG_SH2_CRK 217 221 PF00017 0.522
LIG_SH2_CRK 306 310 PF00017 0.487
LIG_SH2_NCK_1 19 23 PF00017 0.596
LIG_SH2_NCK_1 217 221 PF00017 0.541
LIG_SH2_STAT5 397 400 PF00017 0.660
LIG_SH3_1 19 25 PF00018 0.597
LIG_SH3_1 43 49 PF00018 0.618
LIG_SH3_1 457 463 PF00018 0.592
LIG_SH3_3 163 169 PF00018 0.763
LIG_SH3_3 186 192 PF00018 0.634
LIG_SH3_3 19 25 PF00018 0.637
LIG_SH3_3 199 205 PF00018 0.689
LIG_SH3_3 41 47 PF00018 0.636
LIG_SH3_3 417 423 PF00018 0.640
LIG_SH3_3 457 463 PF00018 0.615
LIG_TRAF2_1 232 235 PF00917 0.534
LIG_TRAF2_1 268 271 PF00917 0.493
LIG_TRAF2_1 345 348 PF00917 0.594
LIG_TRAF2_1 383 386 PF00917 0.595
LIG_WW_1 462 465 PF00397 0.638
MOD_CDK_SPK_2 21 26 PF00069 0.722
MOD_CK1_1 149 155 PF00069 0.690
MOD_CK1_1 281 287 PF00069 0.582
MOD_CK1_1 29 35 PF00069 0.675
MOD_CK1_1 387 393 PF00069 0.625
MOD_CK1_1 408 414 PF00069 0.652
MOD_CK1_1 448 454 PF00069 0.690
MOD_CK1_1 484 490 PF00069 0.666
MOD_CK1_1 54 60 PF00069 0.706
MOD_CK2_1 229 235 PF00069 0.593
MOD_CK2_1 270 276 PF00069 0.530
MOD_CK2_1 281 287 PF00069 0.637
MOD_CK2_1 367 373 PF00069 0.607
MOD_CK2_1 379 385 PF00069 0.712
MOD_CK2_1 399 405 PF00069 0.657
MOD_CK2_1 448 454 PF00069 0.618
MOD_CK2_1 56 62 PF00069 0.779
MOD_GlcNHglycan 148 151 PF01048 0.684
MOD_GlcNHglycan 186 189 PF01048 0.635
MOD_GlcNHglycan 27 31 PF01048 0.679
MOD_GlcNHglycan 479 482 PF01048 0.648
MOD_GSK3_1 301 308 PF00069 0.445
MOD_GSK3_1 335 342 PF00069 0.609
MOD_GSK3_1 380 387 PF00069 0.661
MOD_GSK3_1 395 402 PF00069 0.663
MOD_GSK3_1 410 417 PF00069 0.731
MOD_GSK3_1 441 448 PF00069 0.618
MOD_GSK3_1 471 478 PF00069 0.747
MOD_GSK3_1 52 59 PF00069 0.702
MOD_GSK3_1 7 14 PF00069 0.643
MOD_NEK2_1 193 198 PF00069 0.681
MOD_NEK2_1 206 211 PF00069 0.445
MOD_NEK2_1 305 310 PF00069 0.414
MOD_PIKK_1 270 276 PF00454 0.658
MOD_PIKK_1 405 411 PF00454 0.683
MOD_PIKK_1 471 477 PF00454 0.671
MOD_PKA_2 471 477 PF00069 0.615
MOD_Plk_1 270 276 PF00069 0.581
MOD_Plk_1 384 390 PF00069 0.624
MOD_Plk_1 414 420 PF00069 0.641
MOD_Plk_1 445 451 PF00069 0.652
MOD_Plk_2-3 339 345 PF00069 0.650
MOD_Plk_2-3 380 386 PF00069 0.605
MOD_Plk_4 105 111 PF00069 0.594
MOD_Plk_4 206 212 PF00069 0.486
MOD_Plk_4 281 287 PF00069 0.744
MOD_Plk_4 301 307 PF00069 0.492
MOD_Plk_4 445 451 PF00069 0.531
MOD_Plk_4 481 487 PF00069 0.737
MOD_ProDKin_1 144 150 PF00069 0.786
MOD_ProDKin_1 162 168 PF00069 0.566
MOD_ProDKin_1 21 27 PF00069 0.644
MOD_ProDKin_1 216 222 PF00069 0.577
MOD_ProDKin_1 241 247 PF00069 0.608
MOD_ProDKin_1 260 266 PF00069 0.435
MOD_ProDKin_1 286 292 PF00069 0.503
MOD_ProDKin_1 299 305 PF00069 0.515
MOD_ProDKin_1 484 490 PF00069 0.620
MOD_SUMO_for_1 25 28 PF00179 0.739
MOD_SUMO_rev_2 81 91 PF00179 0.761
MOD_SUMO_rev_2 97 107 PF00179 0.549
TRG_DiLeu_BaEn_3 234 240 PF01217 0.512
TRG_ENDOCYTIC_2 306 309 PF00928 0.480
TRG_ER_diArg_1 259 262 PF00400 0.525
TRG_ER_diArg_1 456 458 PF00400 0.617

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P589 Leptomonas seymouri 31% 68%
A0A3Q8IGZ7 Leishmania donovani 99% 100%
A4H7D5 Leishmania braziliensis 53% 100%
E9B4M2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 100%
Q4Q3F4 Leishmania major 87% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS