H1 histone-like protein

Quick info Annotations Localization Abundance Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

h1 histone-like protein

Species:

Leishmania infantum

UniProt:

A4I9G5_LEIIN

TriTrypDb:

LINF_330042600

Length:

136

Annotations

Annotations by Jardim et al.

Histone/chromosome structure, H1 histone-like

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A4I9G5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I9G5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	10	12	PF00675	0.688
CLV_NRD_NRD_1	134	136	PF00675	0.695
CLV_PCSK_SKI1_1	113	117	PF00082	0.691
CLV_PCSK_SKI1_1	127	131	PF00082	0.495
CLV_PCSK_SKI1_1	74	78	PF00082	0.694
CLV_PCSK_SKI1_1	83	87	PF00082	0.596
DEG_Nend_Nbox_1	1	3	PF02207	0.691
DOC_MAPK_gen_1	90	99	PF00069	0.586
DOC_USP7_MATH_1	88	92	PF00917	0.674
DOC_USP7_UBL2_3	119	123	PF12436	0.638
DOC_USP7_UBL2_3	12	16	PF12436	0.715
DOC_USP7_UBL2_3	86	90	PF12436	0.663
DOC_WW_Pin1_4	34	39	PF00397	0.490
LIG_14-3-3_CanoR_1	3	9	PF00244	0.658
LIG_14-3-3_CanoR_1	54	64	PF00244	0.649
LIG_FHA_1	26	32	PF00498	0.608
LIG_SH3_3	112	118	PF00018	0.445
LIG_SH3_3	39	45	PF00018	0.657
LIG_SH3_3	94	100	PF00018	0.677
MOD_CK1_1	19	25	PF00069	0.695
MOD_CK1_1	91	97	PF00069	0.735
MOD_Cter_Amidation	72	75	PF01082	0.589
MOD_GlcNHglycan	119	122	PF01048	0.645
MOD_GlcNHglycan	21	24	PF01048	0.643
MOD_NEK2_1	2	7	PF00069	0.666
MOD_NEK2_2	49	54	PF00069	0.495
MOD_PIKK_1	55	61	PF00454	0.638
MOD_PKA_2	19	25	PF00069	0.445
MOD_PKA_2	2	8	PF00069	0.662
MOD_PKA_2	91	97	PF00069	0.748
MOD_ProDKin_1	34	40	PF00069	0.492

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IH60	Leishmania donovani	100%	100%
A4HM32	Leishmania braziliensis	60%	100%
E9B4G3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	75%	100%
Q4Q3L2	Leishmania major	82%	100%