Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I9B6_LEIIN

TriTrypDb:

LINF_330036900

Length:

822

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I9B6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I9B6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	128	132	PF00656	0.702
CLV_C14_Caspase3-7	502	506	PF00656	0.673
CLV_C14_Caspase3-7	511	515	PF00656	0.599
CLV_NRD_NRD_1	340	342	PF00675	0.651
CLV_NRD_NRD_1	425	427	PF00675	0.433
CLV_NRD_NRD_1	607	609	PF00675	0.574
CLV_NRD_NRD_1	610	612	PF00675	0.529
CLV_NRD_NRD_1	638	640	PF00675	0.598
CLV_NRD_NRD_1	655	657	PF00675	0.357
CLV_NRD_NRD_1	748	750	PF00675	0.598
CLV_NRD_NRD_1	812	814	PF00675	0.620
CLV_PCSK_FUR_1	605	609	PF00082	0.484
CLV_PCSK_KEX2_1	362	364	PF00082	0.648
CLV_PCSK_KEX2_1	425	427	PF00082	0.455
CLV_PCSK_KEX2_1	607	609	PF00082	0.504
CLV_PCSK_KEX2_1	610	612	PF00082	0.470
CLV_PCSK_KEX2_1	638	640	PF00082	0.598
CLV_PCSK_KEX2_1	655	657	PF00082	0.357
CLV_PCSK_KEX2_1	812	814	PF00082	0.620
CLV_PCSK_PC1ET2_1	362	364	PF00082	0.611
CLV_PCSK_SKI1_1	242	246	PF00082	0.592
CLV_PCSK_SKI1_1	399	403	PF00082	0.659
CLV_PCSK_SKI1_1	431	435	PF00082	0.656
CLV_PCSK_SKI1_1	535	539	PF00082	0.636
CLV_PCSK_SKI1_1	577	581	PF00082	0.610
CLV_PCSK_SKI1_1	584	588	PF00082	0.428
CLV_PCSK_SKI1_1	610	614	PF00082	0.539
CLV_PCSK_SKI1_1	626	630	PF00082	0.457
CLV_PCSK_SKI1_1	655	659	PF00082	0.460
CLV_PCSK_SKI1_1	701	705	PF00082	0.523
CLV_PCSK_SKI1_1	728	732	PF00082	0.564
DEG_APCC_DBOX_1	654	662	PF00400	0.574
DEG_SCF_TRCP1_1	131	136	PF00400	0.709
DEG_SCF_TRCP1_1	63	68	PF00400	0.626
DEG_SPOP_SBC_1	315	319	PF00917	0.656
DOC_CYCLIN_RxL_1	239	248	PF00134	0.592
DOC_CYCLIN_RxL_1	425	438	PF00134	0.649
DOC_CYCLIN_yCln2_LP_2	303	309	PF00134	0.566
DOC_CYCLIN_yCln2_LP_2	575	581	PF00134	0.495
DOC_CYCLIN_yCln2_LP_2	81	87	PF00134	0.592
DOC_MAPK_gen_1	530	539	PF00069	0.575
DOC_MAPK_gen_1	638	644	PF00069	0.517
DOC_MAPK_MEF2A_6	75	83	PF00069	0.595
DOC_PP2B_LxvP_1	303	306	PF13499	0.566
DOC_PP2B_LxvP_1	537	540	PF13499	0.555
DOC_PP4_FxxP_1	83	86	PF00568	0.590
DOC_USP7_MATH_1	258	262	PF00917	0.658
DOC_USP7_MATH_1	316	320	PF00917	0.657
DOC_USP7_MATH_1	403	407	PF00917	0.580
DOC_USP7_MATH_1	506	510	PF00917	0.741
DOC_USP7_MATH_1	512	516	PF00917	0.710
DOC_USP7_MATH_1	689	693	PF00917	0.685
DOC_USP7_MATH_2	278	284	PF00917	0.668
DOC_USP7_UBL2_3	526	530	PF12436	0.611
DOC_WW_Pin1_4	117	122	PF00397	0.638
DOC_WW_Pin1_4	131	136	PF00397	0.649
DOC_WW_Pin1_4	188	193	PF00397	0.719
DOC_WW_Pin1_4	230	235	PF00397	0.684
DOC_WW_Pin1_4	271	276	PF00397	0.728
DOC_WW_Pin1_4	28	33	PF00397	0.682
DOC_WW_Pin1_4	367	372	PF00397	0.722
DOC_WW_Pin1_4	375	380	PF00397	0.713
DOC_WW_Pin1_4	399	404	PF00397	0.586
DOC_WW_Pin1_4	42	47	PF00397	0.659
DOC_WW_Pin1_4	6	11	PF00397	0.669
DOC_WW_Pin1_4	75	80	PF00397	0.667
DOC_WW_Pin1_4	804	809	PF00397	0.692
LIG_14-3-3_CanoR_1	145	151	PF00244	0.698
LIG_14-3-3_CanoR_1	15	23	PF00244	0.727
LIG_14-3-3_CanoR_1	341	347	PF00244	0.648
LIG_14-3-3_CanoR_1	458	462	PF00244	0.558
LIG_14-3-3_CanoR_1	584	589	PF00244	0.664
LIG_14-3-3_CanoR_1	595	601	PF00244	0.453
LIG_Actin_WH2_2	594	612	PF00022	0.519
LIG_Actin_WH2_2	763	779	PF00022	0.502
LIG_BRCT_BRCA1_1	318	322	PF00533	0.595
LIG_BRCT_BRCA1_1	365	369	PF00533	0.622
LIG_BRCT_BRCA1_1	79	83	PF00533	0.597
LIG_FHA_1	198	204	PF00498	0.743
LIG_FHA_1	214	220	PF00498	0.664
LIG_FHA_1	246	252	PF00498	0.656
LIG_FHA_1	298	304	PF00498	0.560
LIG_FHA_1	368	374	PF00498	0.585
LIG_FHA_1	495	501	PF00498	0.690
LIG_FHA_1	588	594	PF00498	0.597
LIG_FHA_1	643	649	PF00498	0.539
LIG_FHA_1	667	673	PF00498	0.496
LIG_FHA_2	101	107	PF00498	0.629
LIG_FHA_2	268	274	PF00498	0.780
LIG_FHA_2	563	569	PF00498	0.542
LIG_FHA_2	731	737	PF00498	0.673
LIG_HCF-1_HBM_1	651	654	PF13415	0.573
LIG_LIR_Apic_2	80	86	PF02991	0.594
LIG_LIR_Gen_1	253	263	PF02991	0.580
LIG_LIR_Gen_1	418	424	PF02991	0.638
LIG_LIR_Gen_1	704	712	PF02991	0.540
LIG_LIR_Nem_3	20	26	PF02991	0.616
LIG_LIR_Nem_3	253	259	PF02991	0.580
LIG_LIR_Nem_3	418	422	PF02991	0.646
LIG_LIR_Nem_3	665	671	PF02991	0.552
LIG_LIR_Nem_3	704	709	PF02991	0.545
LIG_MAD2	154	162	PF02301	0.742
LIG_MYND_1	192	196	PF01753	0.684
LIG_MYND_1	302	306	PF01753	0.600
LIG_PCNA_yPIPBox_3	634	648	PF02747	0.496
LIG_PCNA_yPIPBox_3	792	803	PF02747	0.553
LIG_PDZ_Class_2	817	822	PF00595	0.641
LIG_Pex14_1	453	457	PF04695	0.610
LIG_Pex14_2	596	600	PF04695	0.593
LIG_Pex14_2	683	687	PF04695	0.616
LIG_SH2_STAP1	581	585	PF00017	0.650
LIG_SH2_STAP1	662	666	PF00017	0.499
LIG_SH3_2	140	145	PF14604	0.665
LIG_SH3_3	134	140	PF00018	0.666
LIG_SH3_3	186	192	PF00018	0.728
LIG_SH3_3	204	210	PF00018	0.740
LIG_SH3_3	228	234	PF00018	0.714
LIG_SH3_3	254	260	PF00018	0.694
LIG_SH3_3	272	278	PF00018	0.572
LIG_SH3_3	373	379	PF00018	0.753
LIG_SH3_3	537	543	PF00018	0.659
LIG_SH3_3	83	89	PF00018	0.582
LIG_SUMO_SIM_anti_2	311	321	PF11976	0.582
LIG_SUMO_SIM_anti_2	669	675	PF11976	0.475
LIG_SUMO_SIM_anti_2	91	98	PF11976	0.608
LIG_SUMO_SIM_par_1	584	590	PF11976	0.637
LIG_TRAF2_1	721	724	PF00917	0.540
LIG_WW_2	192	195	PF00397	0.684
MOD_CDK_SPK_2	117	122	PF00069	0.638
MOD_CK1_1	120	126	PF00069	0.603
MOD_CK1_1	17	23	PF00069	0.667
MOD_CK1_1	180	186	PF00069	0.723
MOD_CK1_1	250	256	PF00069	0.652
MOD_CK1_1	27	33	PF00069	0.568
MOD_CK1_1	317	323	PF00069	0.795
MOD_CK1_1	480	486	PF00069	0.764
MOD_CK2_1	122	128	PF00069	0.610
MOD_CK2_1	267	273	PF00069	0.759
MOD_CK2_1	321	327	PF00069	0.631
MOD_CK2_1	6	12	PF00069	0.692
MOD_CK2_1	718	724	PF00069	0.575
MOD_CK2_1	730	736	PF00069	0.556
MOD_CK2_1	772	778	PF00069	0.624
MOD_CK2_1	815	821	PF00069	0.645
MOD_Cter_Amidation	532	535	PF01082	0.612
MOD_DYRK1A_RPxSP_1	75	79	PF00069	0.593
MOD_GlcNHglycan	124	127	PF01048	0.667
MOD_GlcNHglycan	131	134	PF01048	0.680
MOD_GlcNHglycan	179	182	PF01048	0.732
MOD_GlcNHglycan	282	285	PF01048	0.707
MOD_GlcNHglycan	307	310	PF01048	0.673
MOD_GlcNHglycan	327	332	PF01048	0.670
MOD_GlcNHglycan	348	351	PF01048	0.682
MOD_GlcNHglycan	365	368	PF01048	0.582
MOD_GlcNHglycan	392	395	PF01048	0.750
MOD_GlcNHglycan	405	408	PF01048	0.553
MOD_GlcNHglycan	462	465	PF01048	0.644
MOD_GlcNHglycan	482	485	PF01048	0.551
MOD_GlcNHglycan	514	517	PF01048	0.665
MOD_GlcNHglycan	52	55	PF01048	0.643
MOD_GlcNHglycan	63	66	PF01048	0.639
MOD_GlcNHglycan	67	70	PF01048	0.650
MOD_GlcNHglycan	720	723	PF01048	0.537
MOD_GSK3_1	129	136	PF00069	0.668
MOD_GSK3_1	14	21	PF00069	0.669
MOD_GSK3_1	175	182	PF00069	0.792
MOD_GSK3_1	184	191	PF00069	0.714
MOD_GSK3_1	230	237	PF00069	0.726
MOD_GSK3_1	24	31	PF00069	0.608
MOD_GSK3_1	245	252	PF00069	0.493
MOD_GSK3_1	267	274	PF00069	0.742
MOD_GSK3_1	314	321	PF00069	0.778
MOD_GSK3_1	342	349	PF00069	0.705
MOD_GSK3_1	363	370	PF00069	0.592
MOD_GSK3_1	395	402	PF00069	0.714
MOD_GSK3_1	479	486	PF00069	0.749
MOD_GSK3_1	494	501	PF00069	0.546
MOD_GSK3_1	506	513	PF00069	0.603
MOD_GSK3_1	596	603	PF00069	0.443
MOD_GSK3_1	61	68	PF00069	0.721
MOD_GSK3_1	91	98	PF00069	0.612
MOD_N-GLC_1	363	368	PF02516	0.656
MOD_NEK2_1	146	151	PF00069	0.659
MOD_NEK2_1	245	250	PF00069	0.598
MOD_NEK2_1	346	351	PF00069	0.718
MOD_NEK2_1	477	482	PF00069	0.675
MOD_NEK2_1	554	559	PF00069	0.607
MOD_NEK2_1	596	601	PF00069	0.555
MOD_NEK2_1	613	618	PF00069	0.386
MOD_NEK2_1	629	634	PF00069	0.464
MOD_NEK2_1	642	647	PF00069	0.460
MOD_PIKK_1	184	190	PF00454	0.656
MOD_PIKK_1	234	240	PF00454	0.674
MOD_PIKK_1	273	279	PF00454	0.618
MOD_PIKK_1	321	327	PF00454	0.738
MOD_PIKK_1	88	94	PF00454	0.590
MOD_PIKK_1	95	101	PF00454	0.581
MOD_PK_1	798	804	PF00069	0.534
MOD_PKA_2	100	106	PF00069	0.708
MOD_PKA_2	14	20	PF00069	0.684
MOD_PKA_2	415	421	PF00069	0.642
MOD_PKA_2	457	463	PF00069	0.654
MOD_PKA_2	50	56	PF00069	0.607
MOD_PKA_2	716	722	PF00069	0.538
MOD_Plk_2-3	562	568	PF00069	0.614
MOD_Plk_4	342	348	PF00069	0.685
MOD_Plk_4	415	421	PF00069	0.619
MOD_Plk_4	494	500	PF00069	0.646
MOD_Plk_4	554	560	PF00069	0.632
MOD_Plk_4	701	707	PF00069	0.554
MOD_Plk_4	77	83	PF00069	0.642
MOD_Plk_4	798	804	PF00069	0.578
MOD_Plk_4	91	97	PF00069	0.574
MOD_ProDKin_1	117	123	PF00069	0.637
MOD_ProDKin_1	131	137	PF00069	0.647
MOD_ProDKin_1	188	194	PF00069	0.717
MOD_ProDKin_1	230	236	PF00069	0.684
MOD_ProDKin_1	271	277	PF00069	0.728
MOD_ProDKin_1	28	34	PF00069	0.683
MOD_ProDKin_1	367	373	PF00069	0.722
MOD_ProDKin_1	375	381	PF00069	0.715
MOD_ProDKin_1	399	405	PF00069	0.585
MOD_ProDKin_1	42	48	PF00069	0.660
MOD_ProDKin_1	6	12	PF00069	0.670
MOD_ProDKin_1	75	81	PF00069	0.668
MOD_ProDKin_1	804	810	PF00069	0.692
MOD_SUMO_for_1	579	582	PF00179	0.542
TRG_DiLeu_BaLyEn_6	299	304	PF01217	0.582
TRG_DiLeu_BaLyEn_6	329	334	PF01217	0.628
TRG_DiLeu_BaLyEn_6	581	586	PF01217	0.653
TRG_ER_diArg_1	605	608	PF00400	0.509
TRG_ER_diArg_1	609	611	PF00400	0.465
TRG_ER_diArg_1	638	640	PF00400	0.561
TRG_ER_diArg_1	654	656	PF00400	0.364
TRG_ER_diArg_1	693	696	PF00400	0.668
TRG_ER_diArg_1	811	813	PF00400	0.618
TRG_NLS_MonoExtC_3	748	754	PF00514	0.518
TRG_NLS_MonoExtN_4	746	753	PF00514	0.527
TRG_Pf-PMV_PEXEL_1	242	247	PF00026	0.701
TRG_Pf-PMV_PEXEL_1	431	435	PF00026	0.656

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H7V3	Leishmania donovani	100%	90%
A4HLY7	Leishmania braziliensis	52%	100%
E9B4B6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	100%
Q4Q3Q9	Leishmania major	79%	98%