Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I938_LEIIN

TriTrypDb:

LINF_330025000

Length:

204

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I938

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I938

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	169	173	PF00656	0.504
CLV_C14_Caspase3-7	190	194	PF00656	0.518
CLV_C14_Caspase3-7	46	50	PF00656	0.494
CLV_NRD_NRD_1	137	139	PF00675	0.561
CLV_NRD_NRD_1	186	188	PF00675	0.477
CLV_PCSK_KEX2_1	137	139	PF00082	0.561
CLV_PCSK_KEX2_1	186	188	PF00082	0.492
CLV_PCSK_KEX2_1	99	101	PF00082	0.580
CLV_PCSK_PC1ET2_1	99	101	PF00082	0.549
CLV_PCSK_SKI1_1	160	164	PF00082	0.452
DEG_Nend_UBRbox_3	1	3	PF02207	0.696
DOC_PP4_FxxP_1	58	61	PF00568	0.580
DOC_USP7_MATH_1	109	113	PF00917	0.581
DOC_USP7_MATH_1	144	148	PF00917	0.604
DOC_USP7_MATH_1	173	177	PF00917	0.504
DOC_USP7_MATH_1	98	102	PF00917	0.466
DOC_WW_Pin1_4	105	110	PF00397	0.521
LIG_14-3-3_CanoR_1	186	192	PF00244	0.472
LIG_APCC_ABBA_1	149	154	PF00400	0.594
LIG_DLG_GKlike_1	187	195	PF00625	0.518
LIG_FHA_1	106	112	PF00498	0.648
LIG_FHA_1	11	17	PF00498	0.448
LIG_FHA_1	37	43	PF00498	0.480
LIG_LIR_Gen_1	121	132	PF02991	0.482
LIG_LIR_Gen_1	161	170	PF02991	0.483
LIG_LIR_Gen_1	180	189	PF02991	0.349
LIG_LIR_Gen_1	32	41	PF02991	0.534
LIG_LIR_Nem_3	121	127	PF02991	0.530
LIG_LIR_Nem_3	161	165	PF02991	0.552
LIG_LIR_Nem_3	32	36	PF02991	0.426
LIG_SH2_CRK	68	72	PF00017	0.547
LIG_SH2_NCK_1	191	195	PF00017	0.526
LIG_SH2_SRC	191	194	PF00017	0.520
LIG_SH2_STAT5	102	105	PF00017	0.431
LIG_SH2_STAT5	107	110	PF00017	0.474
LIG_SH2_STAT5	124	127	PF00017	0.402
LIG_SH3_3	129	135	PF00018	0.511
LIG_TYR_ITIM	66	71	PF00017	0.416
MOD_CK1_1	118	124	PF00069	0.434
MOD_CK2_1	144	150	PF00069	0.606
MOD_GlcNHglycan	117	120	PF01048	0.568
MOD_GlcNHglycan	146	149	PF01048	0.598
MOD_GSK3_1	105	112	PF00069	0.577
MOD_GSK3_1	173	180	PF00069	0.477
MOD_GSK3_1	56	63	PF00069	0.514
MOD_NEK2_1	10	15	PF00069	0.494
MOD_NEK2_1	143	148	PF00069	0.547
MOD_NEK2_1	185	190	PF00069	0.544
MOD_NEK2_1	36	41	PF00069	0.514
MOD_PIKK_1	138	144	PF00454	0.474
MOD_PKA_2	185	191	PF00069	0.548
MOD_Plk_1	138	144	PF00069	0.542
MOD_Plk_1	195	201	PF00069	0.519
MOD_Plk_4	37	43	PF00069	0.546
MOD_Plk_4	51	57	PF00069	0.325
MOD_ProDKin_1	105	111	PF00069	0.538
TRG_ENDOCYTIC_2	124	127	PF00928	0.471
TRG_ENDOCYTIC_2	68	71	PF00928	0.410
TRG_ER_diArg_1	185	187	PF00400	0.472
TRG_Pf-PMV_PEXEL_1	138	142	PF00026	0.525
TRG_Pf-PMV_PEXEL_1	4	9	PF00026	0.609

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEU1	Leptomonas seymouri	54%	99%
A0A3R7KFM1	Trypanosoma rangeli	26%	94%
A0A3S7X6V4	Leishmania donovani	99%	100%
A4HLM7	Leishmania braziliensis	84%	100%
C9ZIV5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
E9B403	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
Q4Q421	Leishmania major	94%	100%