Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA recognition motif. (a.k.a. RRM - RBD - or RNP domain)/RNA recognition motif (a.k.a. RRM - RBD - or RNP domain) - putative

Species:

Leishmania infantum

UniProt:

A4I918_LEIIN

TriTrypDb:

LINF_330022900

Length:

330

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I918

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I918

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	4
GO:0003723	RNA binding	4	4
GO:0005488	binding	1	4
GO:0097159	organic cyclic compound binding	2	4
GO:1901363	heterocyclic compound binding	2	4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
DEG_SPOP_SBC_1	288	292	PF00917	0.723
DOC_CKS1_1	135	140	PF01111	0.773
DOC_USP7_MATH_1	149	153	PF00917	0.804
DOC_USP7_MATH_1	155	159	PF00917	0.706
DOC_USP7_MATH_1	190	194	PF00917	0.811
DOC_USP7_MATH_1	224	228	PF00917	0.779
DOC_USP7_MATH_1	236	240	PF00917	0.605
DOC_USP7_MATH_1	289	293	PF00917	0.699
DOC_USP7_MATH_1	305	309	PF00917	0.456
DOC_USP7_MATH_1	57	61	PF00917	0.530
DOC_WW_Pin1_4	134	139	PF00397	0.769
DOC_WW_Pin1_4	232	237	PF00397	0.787
DOC_WW_Pin1_4	244	249	PF00397	0.602
DOC_WW_Pin1_4	260	265	PF00397	0.520
DOC_WW_Pin1_4	325	330	PF00397	0.710
LIG_14-3-3_CanoR_1	225	229	PF00244	0.757
LIG_14-3-3_CanoR_1	80	87	PF00244	0.623
LIG_BIR_II_1	1	5	PF00653	0.574
LIG_BRCT_BRCA1_1	11	15	PF00533	0.630
LIG_BRCT_BRCA1_1	193	197	PF00533	0.811
LIG_FHA_1	232	238	PF00498	0.762
LIG_FHA_1	77	83	PF00498	0.481
LIG_FHA_2	112	118	PF00498	0.793
LIG_FHA_2	45	51	PF00498	0.520
LIG_LIR_Gen_1	157	166	PF02991	0.791
LIG_LIR_Gen_1	266	271	PF02991	0.795
LIG_LIR_Nem_3	157	162	PF02991	0.792
LIG_LIR_Nem_3	164	169	PF02991	0.670
LIG_LIR_Nem_3	21	26	PF02991	0.520
LIG_MLH1_MIPbox_1	11	15	PF16413	0.630
LIG_Pex14_2	11	15	PF04695	0.630
LIG_Pex14_2	159	163	PF04695	0.798
LIG_PTAP_UEV_1	254	259	PF05743	0.766
LIG_SH2_CRK	26	30	PF00017	0.630
LIG_SH2_CRK	285	289	PF00017	0.728
LIG_SH2_NCK_1	285	289	PF00017	0.728
LIG_SH2_SRC	324	327	PF00017	0.741
LIG_SH2_STAP1	215	219	PF00017	0.772
LIG_SH2_STAT5	267	270	PF00017	0.799
LIG_SH2_STAT5	324	327	PF00017	0.741
LIG_SH3_3	201	207	PF00018	0.799
LIG_SH3_3	252	258	PF00018	0.786
LIG_SH3_3	265	271	PF00018	0.603
LIG_SH3_3	323	329	PF00018	0.736
LIG_SH3_3	40	46	PF00018	0.574
LIG_TRAF2_1	176	179	PF00917	0.817
LIG_TYR_ITIM	322	327	PF00017	0.737
LIG_WRPW_2	23	26	PF00400	0.630
LIG_WW_1	203	206	PF00397	0.791
MOD_CK1_1	128	134	PF00069	0.760
MOD_CK1_1	158	164	PF00069	0.795
MOD_CK1_1	170	176	PF00069	0.610
MOD_CK1_1	231	237	PF00069	0.788
MOD_CK1_1	239	245	PF00069	0.674
MOD_CK1_1	273	279	PF00069	0.727
MOD_CK1_1	60	66	PF00069	0.615
MOD_CK1_1	76	82	PF00069	0.397
MOD_CK2_1	173	179	PF00069	0.816
MOD_CK2_1	44	50	PF00069	0.520
MOD_GlcNHglycan	105	109	PF01048	0.783
MOD_GlcNHglycan	168	172	PF01048	0.786
MOD_GlcNHglycan	174	178	PF01048	0.721
MOD_GlcNHglycan	216	219	PF01048	0.769
MOD_GlcNHglycan	255	258	PF01048	0.795
MOD_GlcNHglycan	272	275	PF01048	0.491
MOD_GlcNHglycan	291	294	PF01048	0.405
MOD_GlcNHglycan	307	310	PF01048	0.443
MOD_GlcNHglycan	82	85	PF01048	0.615
MOD_GSK3_1	100	107	PF00069	0.550
MOD_GSK3_1	121	128	PF00069	0.720
MOD_GSK3_1	154	161	PF00069	0.773
MOD_GSK3_1	224	231	PF00069	0.784
MOD_GSK3_1	232	239	PF00069	0.661
MOD_GSK3_1	243	250	PF00069	0.490
MOD_GSK3_1	305	312	PF00069	0.698
MOD_GSK3_1	41	48	PF00069	0.533
MOD_GSK3_1	76	83	PF00069	0.474
MOD_GSK3_1	88	95	PF00069	0.491
MOD_N-GLC_1	126	131	PF02516	0.765
MOD_N-GLC_1	155	160	PF02516	0.794
MOD_NEK2_1	126	131	PF00069	0.765
MOD_NEK2_1	139	144	PF00069	0.545
MOD_NEK2_1	162	167	PF00069	0.790
MOD_NEK2_1	213	218	PF00069	0.772
MOD_NEK2_1	228	233	PF00069	0.546
MOD_PIKK_1	65	71	PF00454	0.674
MOD_PKA_2	224	230	PF00069	0.755
MOD_Plk_1	155	161	PF00069	0.792
MOD_Plk_4	158	164	PF00069	0.795
MOD_Plk_4	224	230	PF00069	0.782
MOD_Plk_4	236	242	PF00069	0.607
MOD_Plk_4	263	269	PF00069	0.798
MOD_ProDKin_1	134	140	PF00069	0.771
MOD_ProDKin_1	232	238	PF00069	0.789
MOD_ProDKin_1	244	250	PF00069	0.601
MOD_ProDKin_1	260	266	PF00069	0.523
TRG_DiLeu_BaLyEn_6	77	82	PF01217	0.644
TRG_ENDOCYTIC_2	166	169	PF00928	0.778
TRG_ENDOCYTIC_2	26	29	PF00928	0.520
TRG_ENDOCYTIC_2	267	270	PF00928	0.799
TRG_ENDOCYTIC_2	284	287	PF00928	0.460
TRG_ENDOCYTIC_2	324	327	PF00928	0.741

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H7U5	Leishmania donovani	98%	100%
Q4Q441	Leishmania major	97%	99%