Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA recognition motif. (a.k.a. RRM - RBD - or RNP domain)/RNA recognition motif (a.k.a. RRM - RBD - or RNP domain) - putative

Species:

Leishmania infantum

UniProt:

A4I917_LEIIN

TriTrypDb:

LINF_330022800

Length:

209

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I917

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I917

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003723	RNA binding	4	7
GO:0005488	binding	1	7
GO:0097159	organic cyclic compound binding	2	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	66	68	PF00675	0.759
CLV_PCSK_KEX2_1	110	112	PF00082	0.298
CLV_PCSK_KEX2_1	66	68	PF00082	0.728
CLV_PCSK_PC1ET2_1	110	112	PF00082	0.298
CLV_PCSK_SKI1_1	179	183	PF00082	0.437
CLV_PCSK_SKI1_1	91	95	PF00082	0.282
DEG_Nend_Nbox_1	1	3	PF02207	0.577
DEG_SCF_FBW7_1	194	201	PF00400	0.633
DEG_SCF_FBW7_1	54	61	PF00400	0.733
DOC_CYCLIN_yCln2_LP_2	14	17	PF00134	0.620
DOC_MAPK_gen_1	69	78	PF00069	0.468
DOC_PP2B_LxvP_1	14	17	PF13499	0.620
DOC_USP7_MATH_1	145	149	PF00917	0.396
DOC_USP7_MATH_1	192	196	PF00917	0.474
DOC_USP7_MATH_1	198	202	PF00917	0.518
DOC_WW_Pin1_4	194	199	PF00397	0.492
DOC_WW_Pin1_4	54	59	PF00397	0.728
LIG_APCC_ABBA_1	182	187	PF00400	0.458
LIG_BRCT_BRCA1_1	129	133	PF00533	0.436
LIG_FHA_1	168	174	PF00498	0.426
LIG_FHA_1	197	203	PF00498	0.521
LIG_FHA_2	136	142	PF00498	0.415
LIG_FHA_2	84	90	PF00498	0.505
LIG_LIR_Nem_3	130	136	PF02991	0.419
LIG_LIR_Nem_3	92	97	PF02991	0.502
LIG_SH2_NCK_1	60	64	PF00017	0.599
LIG_SH2_STAP1	204	208	PF00017	0.556
LIG_SH2_STAT3	38	41	PF00017	0.566
LIG_SH2_STAT5	153	156	PF00017	0.478
LIG_SH2_STAT5	166	169	PF00017	0.270
LIG_SH2_STAT5	38	41	PF00017	0.703
LIG_SH3_3	10	16	PF00018	0.578
LIG_SH3_3	131	137	PF00018	0.543
LIG_SH3_3	186	192	PF00018	0.499
LIG_SH3_3	59	65	PF00018	0.735
LIG_SUMO_SIM_anti_2	143	148	PF11976	0.412
LIG_SUMO_SIM_par_1	102	109	PF11976	0.505
LIG_WW_3	63	67	PF00397	0.731
MOD_CK2_1	135	141	PF00069	0.418
MOD_GlcNHglycan	130	133	PF01048	0.409
MOD_GlcNHglycan	20	23	PF01048	0.644
MOD_GSK3_1	128	135	PF00069	0.425
MOD_GSK3_1	167	174	PF00069	0.424
MOD_GSK3_1	192	199	PF00069	0.483
MOD_GSK3_1	54	61	PF00069	0.733
MOD_NEK2_1	106	111	PF00069	0.498
MOD_NEK2_1	36	41	PF00069	0.711
MOD_NEK2_1	49	54	PF00069	0.555
MOD_NEK2_2	145	150	PF00069	0.408
MOD_PIKK_1	116	122	PF00454	0.566
MOD_Plk_4	15	21	PF00069	0.623
MOD_ProDKin_1	194	200	PF00069	0.500
MOD_ProDKin_1	54	60	PF00069	0.731
TRG_ENDOCYTIC_2	97	100	PF00928	0.498
TRG_ER_diArg_1	65	67	PF00400	0.766

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P505	Leptomonas seymouri	77%	100%
A0A3S7X6S0	Leishmania donovani	100%	100%
A4HLK6	Leishmania braziliensis	84%	100%
E9B3Y2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
Q4Q442	Leishmania major	98%	100%