Putative 33 kDa inner dynein arm light chain, axonemal

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Axonemal inner arm dynein light chain - putative

Species:

Leishmania infantum

UniProt:

A4I8Y3_LEIIN

TriTrypDb:

LINF_330019400

Length:

247

Annotations

Annotations by Jardim et al.

Structural Proteins, 33 kDa inner dynein arm light chain, axonemal

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005930	axoneme	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4I8Y3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I8Y3

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	1
GO:0005515	protein binding	2	1
GO:0045504	dynein heavy chain binding	3	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	201	203	PF00675	0.265
CLV_NRD_NRD_1	86	88	PF00675	0.307
CLV_NRD_NRD_1	97	99	PF00675	0.307
CLV_PCSK_KEX2_1	201	203	PF00082	0.282
CLV_PCSK_KEX2_1	81	83	PF00082	0.331
CLV_PCSK_KEX2_1	86	88	PF00082	0.281
CLV_PCSK_KEX2_1	97	99	PF00082	0.238
CLV_PCSK_PC1ET2_1	81	83	PF00082	0.219
CLV_PCSK_PC7_1	82	88	PF00082	0.219
CLV_PCSK_SKI1_1	110	114	PF00082	0.240
CLV_PCSK_SKI1_1	119	123	PF00082	0.302
CLV_PCSK_SKI1_1	173	177	PF00082	0.219
CLV_PCSK_SKI1_1	97	101	PF00082	0.288
CLV_Separin_Metazoa	107	111	PF03568	0.219
DEG_Nend_UBRbox_3	1	3	PF02207	0.476
DOC_MAPK_gen_1	170	178	PF00069	0.331
DOC_MAPK_MEF2A_6	170	178	PF00069	0.277
DOC_WW_Pin1_4	35	40	PF00397	0.526
LIG_14-3-3_CanoR_1	110	115	PF00244	0.247
LIG_APCC_ABBAyCdc20_2	97	103	PF00400	0.247
LIG_FHA_1	11	17	PF00498	0.496
LIG_FHA_2	111	117	PF00498	0.307
LIG_FHA_2	184	190	PF00498	0.258
LIG_FHA_2	225	231	PF00498	0.425
LIG_LIR_Gen_1	103	112	PF02991	0.268
LIG_LIR_Nem_3	103	108	PF02991	0.283
LIG_SH2_STAT5	101	104	PF00017	0.278
LIG_SH2_STAT5	211	214	PF00017	0.307
LIG_SH3_3	111	117	PF00018	0.219
LIG_SUMO_SIM_par_1	54	61	PF11976	0.552
LIG_TRAF2_1	113	116	PF00917	0.307
LIG_TRAF2_1	48	51	PF00917	0.572
LIG_UBA3_1	183	188	PF00899	0.307
MOD_CK1_1	40	46	PF00069	0.533
MOD_CK1_1	58	64	PF00069	0.223
MOD_CK2_1	110	116	PF00069	0.284
MOD_CK2_1	183	189	PF00069	0.254
MOD_CK2_1	224	230	PF00069	0.421
MOD_GlcNHglycan	230	233	PF01048	0.469
MOD_GlcNHglycan	26	29	PF01048	0.461
MOD_GlcNHglycan	39	42	PF01048	0.465
MOD_GlcNHglycan	62	65	PF01048	0.311
MOD_GSK3_1	224	231	PF00069	0.512
MOD_GSK3_1	31	38	PF00069	0.550
MOD_NEK2_1	147	152	PF00069	0.285
MOD_NEK2_1	16	21	PF00069	0.461
MOD_NEK2_1	183	188	PF00069	0.372
MOD_NEK2_1	75	80	PF00069	0.443
MOD_PKA_2	228	234	PF00069	0.534
MOD_PKA_2	88	94	PF00069	0.283
MOD_Plk_4	16	22	PF00069	0.418
MOD_ProDKin_1	35	41	PF00069	0.528
MOD_SUMO_for_1	223	226	PF00179	0.402
MOD_SUMO_rev_2	207	212	PF00179	0.377
TRG_DiLeu_BaEn_2	142	148	PF01217	0.200
TRG_DiLeu_BaEn_4	195	201	PF01217	0.311
TRG_ENDOCYTIC_2	101	104	PF00928	0.303
TRG_ER_diArg_1	200	202	PF00400	0.271
TRG_ER_diArg_1	86	89	PF00400	0.336
TRG_ER_diArg_1	96	98	PF00400	0.307
TRG_Pf-PMV_PEXEL_1	8	12	PF00026	0.421
TRG_Pf-PMV_PEXEL_1	81	85	PF00026	0.203
TRG_Pf-PMV_PEXEL_1	98	103	PF00026	0.153

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBX9	Leptomonas seymouri	39%	100%
A0A0S4J6T9	Bodo saltans	42%	98%
A0A0S4J9S1	Bodo saltans	36%	100%
A0A0S4JQQ4	Bodo saltans	32%	100%
A0A1X0NVG2	Trypanosomatidae	38%	100%
A0A1X0NXR5	Trypanosomatidae	34%	80%
A0A3Q8IC16	Leishmania donovani	36%	100%
A0A3Q8IM75	Leishmania donovani	100%	100%
A0A3R7KMX9	Trypanosoma rangeli	36%	100%
A0A422MW64	Trypanosoma rangeli	41%	66%
A4HBW2	Leishmania braziliensis	34%	79%
A4I0S3	Leishmania infantum	36%	100%
C9ZRW3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	81%
D0A1A2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	90%
D0A4Y1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	66%
D0A753	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
E9AIH0	Leishmania braziliensis	38%	100%
E9AWS5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	100%
E9B3V2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
O14645	Homo sapiens	37%	96%
Q26630	Strongylocentrotus purpuratus	37%	95%
Q39604	Chlamydomonas reinhardtii	37%	98%
Q4FZV3	Rattus norvegicus	37%	96%
Q4Q472	Leishmania major	97%	100%
Q4QAP9	Leishmania major	36%	100%
Q4R3K5	Macaca fascicularis	37%	96%
Q6GN86	Xenopus laevis	38%	97%
Q8BVN8	Mus musculus	37%	96%
Q9VGG6	Drosophila melanogaster	33%	99%
V5B9Q0	Trypanosoma cruzi	36%	68%
V5BR59	Trypanosoma cruzi	37%	100%