Putative calcium-transporting ATPase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

calcium-transporting ATPase - putative

Species:

Leishmania infantum

UniProt:

A4I8W5_LEIIN

TriTrypDb:

LINF_330017500

Length:

1197

Annotations

LeishMANIAdb annotations

Homologous to other eukaryotic P-type Ca2+ ATPases.. For some reason, this group has heavily expanded in Kinetoplastida.. Localization: Endosomal (by homology) / ER (by homology)

Annotations by Jardim et al.

Transporters, calcium-transporting ATPase

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	13
GO:0110165	cellular anatomical entity	1	13
GO:0005783	endoplasmic reticulum	5	1
GO:0043226	organelle	2	3
GO:0043227	membrane-bounded organelle	3	3
GO:0043229	intracellular organelle	3	3
GO:0043231	intracellular membrane-bounded organelle	4	3
GO:0005886	plasma membrane	3	2

Expansion

Sequence features

A4I8W5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I8W5

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	1
GO:0006811	monoatomic ion transport	4	1
GO:0006812	monoatomic cation transport	5	1
GO:0006816	calcium ion transport	7	1
GO:0006873	intracellular monoatomic ion homeostasis	4	1
GO:0006874	intracellular calcium ion homeostasis	7	1
GO:0006875	obsolete intracellular metal ion homeostasis	6	1
GO:0009987	cellular process	1	1
GO:0019725	cellular homeostasis	2	1
GO:0030001	metal ion transport	6	1
GO:0030003	intracellular monoatomic cation homeostasis	5	1
GO:0034220	monoatomic ion transmembrane transport	3	1
GO:0042592	homeostatic process	3	1
GO:0048878	chemical homeostasis	4	1
GO:0050801	monoatomic ion homeostasis	5	1
GO:0051179	localization	1	1
GO:0051234	establishment of localization	2	1
GO:0055065	obsolete metal ion homeostasis	7	1
GO:0055074	calcium ion homeostasis	8	1
GO:0055080	monoatomic cation homeostasis	6	1
GO:0055082	intracellular chemical homeostasis	3	1
GO:0055085	transmembrane transport	2	1
GO:0065007	biological regulation	1	1
GO:0065008	regulation of biological quality	2	1
GO:0070588	calcium ion transmembrane transport	6	1
GO:0072503	obsolete cellular divalent inorganic cation homeostasis	6	1
GO:0072507	obsolete divalent inorganic cation homeostasis	7	1
GO:0098655	monoatomic cation transmembrane transport	4	1
GO:0098660	inorganic ion transmembrane transport	4	1
GO:0098662	inorganic cation transmembrane transport	5	1
GO:0098771	inorganic ion homeostasis	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	13
GO:0003824	catalytic activity	1	13
GO:0005488	binding	1	13
GO:0005524	ATP binding	5	13
GO:0016462	pyrophosphatase activity	5	13
GO:0016787	hydrolase activity	2	13
GO:0016817	hydrolase activity, acting on acid anhydrides	3	13
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	13
GO:0016887	ATP hydrolysis activity	7	13
GO:0017076	purine nucleotide binding	4	13
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	13
GO:0030554	adenyl nucleotide binding	5	13
GO:0032553	ribonucleotide binding	3	13
GO:0032555	purine ribonucleotide binding	4	13
GO:0032559	adenyl ribonucleotide binding	5	13
GO:0035639	purine ribonucleoside triphosphate binding	4	13
GO:0036094	small molecule binding	2	13
GO:0043167	ion binding	2	13
GO:0043168	anion binding	3	13
GO:0097159	organic cyclic compound binding	2	13
GO:0097367	carbohydrate derivative binding	2	13
GO:1901265	nucleoside phosphate binding	3	13
GO:1901363	heterocyclic compound binding	2	13
GO:0005215	transporter activity	1	3
GO:0005388	P-type calcium transporter activity	4	3
GO:0008324	monoatomic cation transmembrane transporter activity	4	3
GO:0015075	monoatomic ion transmembrane transporter activity	3	3
GO:0015085	calcium ion transmembrane transporter activity	6	3
GO:0015318	inorganic molecular entity transmembrane transporter activity	3	3
GO:0015399	primary active transmembrane transporter activity	4	3
GO:0015662	P-type ion transporter activity	4	3
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	3	3
GO:0022804	active transmembrane transporter activity	3	3
GO:0022853	active monoatomic ion transmembrane transporter activity	4	3
GO:0022857	transmembrane transporter activity	2	3
GO:0022890	inorganic cation transmembrane transporter activity	4	3
GO:0042626	ATPase-coupled transmembrane transporter activity	2	3
GO:0046873	metal ion transmembrane transporter activity	5	3
GO:0140358	P-type transmembrane transporter activity	3	3
GO:0140657	ATP-dependent activity	1	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	188	192	PF00656	0.590
CLV_C14_Caspase3-7	261	265	PF00656	0.403
CLV_C14_Caspase3-7	775	779	PF00656	0.657
CLV_NRD_NRD_1	1185	1187	PF00675	0.373
CLV_NRD_NRD_1	147	149	PF00675	0.357
CLV_NRD_NRD_1	165	167	PF00675	0.316
CLV_NRD_NRD_1	481	483	PF00675	0.360
CLV_NRD_NRD_1	50	52	PF00675	0.266
CLV_NRD_NRD_1	560	562	PF00675	0.312
CLV_NRD_NRD_1	723	725	PF00675	0.342
CLV_NRD_NRD_1	874	876	PF00675	0.216
CLV_NRD_NRD_1	941	943	PF00675	0.247
CLV_PCSK_FUR_1	1183	1187	PF00082	0.355
CLV_PCSK_FUR_1	558	562	PF00082	0.260
CLV_PCSK_KEX2_1	1168	1170	PF00082	0.360
CLV_PCSK_KEX2_1	1185	1187	PF00082	0.383
CLV_PCSK_KEX2_1	164	166	PF00082	0.345
CLV_PCSK_KEX2_1	481	483	PF00082	0.360
CLV_PCSK_KEX2_1	5	7	PF00082	0.307
CLV_PCSK_KEX2_1	50	52	PF00082	0.269
CLV_PCSK_KEX2_1	560	562	PF00082	0.304
CLV_PCSK_KEX2_1	723	725	PF00082	0.342
CLV_PCSK_KEX2_1	867	869	PF00082	0.275
CLV_PCSK_KEX2_1	874	876	PF00082	0.223
CLV_PCSK_KEX2_1	912	914	PF00082	0.203
CLV_PCSK_PC1ET2_1	1168	1170	PF00082	0.330
CLV_PCSK_PC1ET2_1	5	7	PF00082	0.305
CLV_PCSK_PC1ET2_1	867	869	PF00082	0.274
CLV_PCSK_PC1ET2_1	912	914	PF00082	0.203
CLV_PCSK_PC7_1	477	483	PF00082	0.355
CLV_PCSK_SKI1_1	1168	1172	PF00082	0.340
CLV_PCSK_SKI1_1	1178	1182	PF00082	0.362
CLV_PCSK_SKI1_1	1186	1190	PF00082	0.380
CLV_PCSK_SKI1_1	165	169	PF00082	0.300
CLV_PCSK_SKI1_1	248	252	PF00082	0.270
CLV_PCSK_SKI1_1	328	332	PF00082	0.303
CLV_PCSK_SKI1_1	377	381	PF00082	0.230
CLV_PCSK_SKI1_1	417	421	PF00082	0.257
CLV_PCSK_SKI1_1	482	486	PF00082	0.346
CLV_PCSK_SKI1_1	867	871	PF00082	0.301
CLV_PCSK_SKI1_1	935	939	PF00082	0.248
CLV_PCSK_SKI1_1	942	946	PF00082	0.272
CLV_Separin_Metazoa	1060	1064	PF03568	0.270
CLV_Separin_Metazoa	155	159	PF03568	0.552
DEG_APCC_DBOX_1	1177	1185	PF00400	0.580
DEG_APCC_DBOX_1	49	57	PF00400	0.416
DEG_COP1_1	1009	1020	PF00400	0.454
DEG_COP1_1	406	414	PF00400	0.438
DOC_ANK_TNKS_1	689	696	PF00023	0.515
DOC_CKS1_1	109	114	PF01111	0.384
DOC_CYCLIN_RxL_1	1173	1182	PF00134	0.542
DOC_CYCLIN_RxL_1	938	950	PF00134	0.465
DOC_CYCLIN_yClb5_NLxxxL_5	380	389	PF00134	0.496
DOC_CYCLIN_yCln2_LP_2	251	257	PF00134	0.460
DOC_CYCLIN_yCln2_LP_2	578	584	PF00134	0.393
DOC_MAPK_gen_1	481	488	PF00069	0.505
DOC_MAPK_gen_1	63	71	PF00069	0.452
DOC_MAPK_gen_1	866	872	PF00069	0.461
DOC_MAPK_gen_1	912	920	PF00069	0.409
DOC_MAPK_MEF2A_6	115	123	PF00069	0.323
DOC_MAPK_MEF2A_6	481	488	PF00069	0.504
DOC_MAPK_MEF2A_6	974	983	PF00069	0.230
DOC_PP1_RVXF_1	941	948	PF00149	0.453
DOC_PP2B_LxvP_1	198	201	PF13499	0.417
DOC_PP2B_LxvP_1	409	412	PF13499	0.517
DOC_PP2B_LxvP_1	578	581	PF13499	0.412
DOC_PP2B_PxIxI_1	852	858	PF00149	0.510
DOC_PP4_FxxP_1	461	464	PF00568	0.635
DOC_USP7_MATH_1	101	105	PF00917	0.478
DOC_USP7_MATH_1	174	178	PF00917	0.543
DOC_USP7_MATH_1	234	238	PF00917	0.416
DOC_USP7_MATH_1	452	456	PF00917	0.656
DOC_USP7_MATH_1	563	567	PF00917	0.444
DOC_USP7_MATH_1	618	622	PF00917	0.505
DOC_USP7_MATH_1	76	80	PF00917	0.492
DOC_USP7_MATH_1	963	967	PF00917	0.345
DOC_WW_Pin1_4	108	113	PF00397	0.372
DOC_WW_Pin1_4	26	31	PF00397	0.567
DOC_WW_Pin1_4	294	299	PF00397	0.461
DOC_WW_Pin1_4	335	340	PF00397	0.427
DOC_WW_Pin1_4	444	449	PF00397	0.673
DOC_WW_Pin1_4	470	475	PF00397	0.745
DOC_WW_Pin1_4	737	742	PF00397	0.621
DOC_WW_Pin1_4	769	774	PF00397	0.737
DOC_WW_Pin1_4	820	825	PF00397	0.586
DOC_WW_Pin1_4	859	864	PF00397	0.500
DOC_WW_Pin1_4	968	973	PF00397	0.330
LIG_14-3-3_CanoR_1	1066	1075	PF00244	0.337
LIG_14-3-3_CanoR_1	1183	1189	PF00244	0.588
LIG_14-3-3_CanoR_1	164	170	PF00244	0.564
LIG_14-3-3_CanoR_1	454	464	PF00244	0.623
LIG_14-3-3_CanoR_1	481	487	PF00244	0.538
LIG_14-3-3_CanoR_1	543	550	PF00244	0.517
LIG_14-3-3_CanoR_1	561	570	PF00244	0.429
LIG_14-3-3_CanoR_1	605	610	PF00244	0.485
LIG_14-3-3_CanoR_1	729	737	PF00244	0.574
LIG_14-3-3_CanoR_1	840	848	PF00244	0.506
LIG_14-3-3_CanoR_1	868	873	PF00244	0.450
LIG_14-3-3_CanoR_1	913	920	PF00244	0.403
LIG_Actin_WH2_2	365	383	PF00022	0.460
LIG_AP2alpha_2	253	255	PF02296	0.403
LIG_BIR_III_2	430	434	PF00653	0.554
LIG_BIR_III_4	648	652	PF00653	0.530
LIG_BRCT_BRCA1_1	1018	1022	PF00533	0.421
LIG_BRCT_BRCA1_1	1096	1100	PF00533	0.431
LIG_BRCT_BRCA1_1	697	701	PF00533	0.460
LIG_deltaCOP1_diTrp_1	78	83	PF00928	0.444
LIG_EH1_1	1110	1118	PF00400	0.220
LIG_EH1_1	373	381	PF00400	0.403
LIG_EH1_1	676	684	PF00400	0.474
LIG_EVH1_2	466	470	PF00568	0.628
LIG_FHA_1	1011	1017	PF00498	0.457
LIG_FHA_1	1027	1033	PF00498	0.423
LIG_FHA_1	1050	1056	PF00498	0.225
LIG_FHA_1	1132	1138	PF00498	0.225
LIG_FHA_1	114	120	PF00498	0.381
LIG_FHA_1	1150	1156	PF00498	0.348
LIG_FHA_1	188	194	PF00498	0.622
LIG_FHA_1	284	290	PF00498	0.384
LIG_FHA_1	348	354	PF00498	0.429
LIG_FHA_1	367	373	PF00498	0.572
LIG_FHA_1	404	410	PF00498	0.515
LIG_FHA_1	411	417	PF00498	0.529
LIG_FHA_1	423	429	PF00498	0.534
LIG_FHA_1	451	457	PF00498	0.659
LIG_FHA_1	483	489	PF00498	0.503
LIG_FHA_1	605	611	PF00498	0.450
LIG_FHA_1	758	764	PF00498	0.607
LIG_FHA_1	772	778	PF00498	0.565
LIG_FHA_1	783	789	PF00498	0.585
LIG_FHA_1	843	849	PF00498	0.484
LIG_FHA_2	108	114	PF00498	0.415
LIG_FHA_2	1136	1142	PF00498	0.221
LIG_FHA_2	186	192	PF00498	0.672
LIG_FHA_2	439	445	PF00498	0.629
LIG_FHA_2	533	539	PF00498	0.470
LIG_FHA_2	860	866	PF00498	0.480
LIG_LIR_Apic_2	458	464	PF02991	0.623
LIG_LIR_Gen_1	1028	1038	PF02991	0.284
LIG_LIR_Gen_1	1079	1089	PF02991	0.268
LIG_LIR_Gen_1	1141	1149	PF02991	0.274
LIG_LIR_Gen_1	151	159	PF02991	0.598
LIG_LIR_Gen_1	220	229	PF02991	0.420
LIG_LIR_Gen_1	321	330	PF02991	0.407
LIG_LIR_Gen_1	676	685	PF02991	0.513
LIG_LIR_Gen_1	78	88	PF02991	0.453
LIG_LIR_Nem_3	1019	1024	PF02991	0.476
LIG_LIR_Nem_3	1079	1085	PF02991	0.300
LIG_LIR_Nem_3	1141	1147	PF02991	0.257
LIG_LIR_Nem_3	151	156	PF02991	0.622
LIG_LIR_Nem_3	220	224	PF02991	0.406
LIG_LIR_Nem_3	321	325	PF02991	0.418
LIG_LIR_Nem_3	329	334	PF02991	0.440
LIG_LIR_Nem_3	676	680	PF02991	0.546
LIG_LIR_Nem_3	78	84	PF02991	0.479
LIG_LIR_Nem_3	837	842	PF02991	0.526
LIG_NRBOX	16	22	PF00104	0.459
LIG_NRBOX	868	874	PF00104	0.546
LIG_NRP_CendR_1	1194	1197	PF00754	0.410
LIG_Pex14_1	1082	1086	PF04695	0.304
LIG_Pex14_2	1022	1026	PF04695	0.467
LIG_Pex14_2	1100	1104	PF04695	0.405
LIG_Pex14_2	132	136	PF04695	0.216
LIG_PTB_Apo_2	918	925	PF02174	0.409
LIG_REV1ctd_RIR_1	1086	1096	PF16727	0.223
LIG_SH2_CRK	1041	1045	PF00017	0.214
LIG_SH2_CRK	1144	1148	PF00017	0.241
LIG_SH2_CRK	172	176	PF00017	0.496
LIG_SH2_GRB2like	609	612	PF00017	0.538
LIG_SH2_GRB2like	790	793	PF00017	0.610
LIG_SH2_SRC	790	793	PF00017	0.606
LIG_SH2_SRC	851	854	PF00017	0.467
LIG_SH2_STAP1	1144	1148	PF00017	0.241
LIG_SH2_STAP1	1166	1170	PF00017	0.528
LIG_SH2_STAP1	22	26	PF00017	0.490
LIG_SH2_STAP1	341	345	PF00017	0.444
LIG_SH2_STAP1	374	378	PF00017	0.460
LIG_SH2_STAT3	147	150	PF00017	0.504
LIG_SH2_STAT5	1067	1070	PF00017	0.221
LIG_SH2_STAT5	333	336	PF00017	0.481
LIG_SH2_STAT5	609	612	PF00017	0.520
LIG_SH2_STAT5	634	637	PF00017	0.493
LIG_SH2_STAT5	851	854	PF00017	0.471
LIG_SH3_2	463	468	PF14604	0.606
LIG_SH3_3	1051	1057	PF00018	0.196
LIG_SH3_3	1059	1065	PF00018	0.174
LIG_SH3_3	355	361	PF00018	0.444
LIG_SH3_3	460	466	PF00018	0.680
LIG_SH3_3	483	489	PF00018	0.503
LIG_SH3_3	612	618	PF00018	0.542
LIG_SH3_3	688	694	PF00018	0.512
LIG_SH3_3	749	755	PF00018	0.617
LIG_SH3_3	969	975	PF00018	0.230
LIG_SH3_3	995	1001	PF00018	0.468
LIG_SH3_CIN85_PxpxPR_1	463	468	PF14604	0.606
LIG_SUMO_SIM_anti_2	268	274	PF11976	0.456
LIG_SUMO_SIM_anti_2	350	357	PF11976	0.430
LIG_SUMO_SIM_anti_2	915	922	PF11976	0.450
LIG_SUMO_SIM_par_1	1121	1126	PF11976	0.418
LIG_SUMO_SIM_par_1	356	362	PF11976	0.444
LIG_SUMO_SIM_par_1	364	369	PF11976	0.444
LIG_SUMO_SIM_par_1	406	413	PF11976	0.438
LIG_SUMO_SIM_par_1	706	711	PF11976	0.453
LIG_SUMO_SIM_par_1	915	922	PF11976	0.450
LIG_TRAF2_1	40	43	PF00917	0.560
LIG_TRAF2_2	824	829	PF00917	0.556
LIG_TYR_ITIM	1039	1044	PF00017	0.220
LIG_UBA3_1	1003	1011	PF00899	0.163
LIG_UBA3_1	1180	1189	PF00899	0.453
LIG_WRC_WIRS_1	1077	1082	PF05994	0.275
LIG_WRC_WIRS_1	319	324	PF05994	0.223
LIG_WRC_WIRS_1	439	444	PF05994	0.534
LIG_WRC_WIRS_1	539	544	PF05994	0.281
LIG_WRC_WIRS_1	957	962	PF05994	0.300
LIG_WW_3	1060	1064	PF00397	0.194
LIG_WW_3	465	469	PF00397	0.509
LIG_WW_3	478	482	PF00397	0.445
MOD_CDC14_SPxK_1	971	974	PF00782	0.261
MOD_CDK_SPxK_1	968	974	PF00069	0.261
MOD_CDK_SPxxK_3	108	115	PF00069	0.386
MOD_CDK_SPxxK_3	470	477	PF00069	0.536
MOD_CDK_SPxxK_3	859	866	PF00069	0.347
MOD_CK1_1	1010	1016	PF00069	0.349
MOD_CK1_1	1187	1193	PF00069	0.604
MOD_CK1_1	237	243	PF00069	0.376
MOD_CK1_1	258	264	PF00069	0.259
MOD_CK1_1	288	294	PF00069	0.304
MOD_CK1_1	422	428	PF00069	0.567
MOD_CK1_1	455	461	PF00069	0.545
MOD_CK1_1	473	479	PF00069	0.626
MOD_CK1_1	532	538	PF00069	0.261
MOD_CK1_1	565	571	PF00069	0.308
MOD_CK1_1	756	762	PF00069	0.566
MOD_CK2_1	1135	1141	PF00069	0.314
MOD_CK2_1	37	43	PF00069	0.560
MOD_CK2_1	56	62	PF00069	0.279
MOD_CK2_1	769	775	PF00069	0.506
MOD_CK2_1	794	800	PF00069	0.514
MOD_CK2_1	840	846	PF00069	0.459
MOD_Cter_Amidation	1194	1197	PF01082	0.635
MOD_GlcNHglycan	1046	1049	PF01048	0.367
MOD_GlcNHglycan	1057	1060	PF01048	0.257
MOD_GlcNHglycan	1106	1109	PF01048	0.205
MOD_GlcNHglycan	1149	1152	PF01048	0.249
MOD_GlcNHglycan	1189	1192	PF01048	0.672
MOD_GlcNHglycan	176	179	PF01048	0.482
MOD_GlcNHglycan	213	216	PF01048	0.308
MOD_GlcNHglycan	257	260	PF01048	0.229
MOD_GlcNHglycan	264	268	PF01048	0.261
MOD_GlcNHglycan	281	284	PF01048	0.184
MOD_GlcNHglycan	39	42	PF01048	0.500
MOD_GlcNHglycan	421	424	PF01048	0.439
MOD_GlcNHglycan	43	47	PF01048	0.415
MOD_GlcNHglycan	636	639	PF01048	0.440
MOD_GlcNHglycan	733	736	PF01048	0.612
MOD_GlcNHglycan	791	795	PF01048	0.746
MOD_GlcNHglycan	805	808	PF01048	0.476
MOD_GlcNHglycan	829	832	PF01048	0.620
MOD_GlcNHglycan	877	881	PF01048	0.254
MOD_GlcNHglycan	953	956	PF01048	0.220
MOD_GSK3_1	1131	1138	PF00069	0.252
MOD_GSK3_1	183	190	PF00069	0.633
MOD_GSK3_1	26	33	PF00069	0.546
MOD_GSK3_1	279	286	PF00069	0.306
MOD_GSK3_1	288	295	PF00069	0.270
MOD_GSK3_1	364	371	PF00069	0.224
MOD_GSK3_1	396	403	PF00069	0.366
MOD_GSK3_1	510	517	PF00069	0.438
MOD_GSK3_1	528	535	PF00069	0.268
MOD_GSK3_1	538	545	PF00069	0.386
MOD_GSK3_1	634	641	PF00069	0.326
MOD_GSK3_1	708	715	PF00069	0.315
MOD_GSK3_1	753	760	PF00069	0.537
MOD_GSK3_1	790	797	PF00069	0.506
MOD_GSK3_1	816	823	PF00069	0.409
MOD_GSK3_1	882	889	PF00069	0.273
MOD_GSK3_1	947	954	PF00069	0.257
MOD_N-GLC_1	347	352	PF02516	0.233
MOD_N-GLC_1	513	518	PF02516	0.282
MOD_N-GLC_1	783	788	PF02516	0.675
MOD_N-GLC_1	820	825	PF02516	0.409
MOD_N-GLC_1	951	956	PF02516	0.450
MOD_N-GLC_1	968	973	PF02516	0.270
MOD_N-GLC_2	37	39	PF02516	0.439
MOD_NEK2_1	1002	1007	PF00069	0.281
MOD_NEK2_1	1026	1031	PF00069	0.322
MOD_NEK2_1	107	112	PF00069	0.419
MOD_NEK2_1	1076	1081	PF00069	0.286
MOD_NEK2_1	1147	1152	PF00069	0.305
MOD_NEK2_1	1184	1189	PF00069	0.454
MOD_NEK2_1	136	141	PF00069	0.375
MOD_NEK2_1	225	230	PF00069	0.392
MOD_NEK2_1	255	260	PF00069	0.249
MOD_NEK2_1	366	371	PF00069	0.298
MOD_NEK2_1	372	377	PF00069	0.261
MOD_NEK2_1	527	532	PF00069	0.322
MOD_NEK2_1	542	547	PF00069	0.249
MOD_NEK2_1	743	748	PF00069	0.656
MOD_NEK2_1	782	787	PF00069	0.480
MOD_NEK2_1	803	808	PF00069	0.573
MOD_NEK2_1	827	832	PF00069	0.507
MOD_NEK2_1	83	88	PF00069	0.393
MOD_NEK2_1	947	952	PF00069	0.295
MOD_NEK2_2	452	457	PF00069	0.523
MOD_NEK2_2	745	750	PF00069	0.519
MOD_PIKK_1	532	538	PF00454	0.220
MOD_PIKK_1	542	548	PF00454	0.220
MOD_PIKK_1	695	701	PF00454	0.305
MOD_PIKK_1	70	76	PF00454	0.236
MOD_PKA_1	165	171	PF00069	0.401
MOD_PKA_1	912	918	PF00069	0.223
MOD_PKA_2	1164	1170	PF00069	0.481
MOD_PKA_2	1184	1190	PF00069	0.437
MOD_PKA_2	165	171	PF00069	0.378
MOD_PKA_2	510	516	PF00069	0.291
MOD_PKA_2	542	548	PF00069	0.292
MOD_PKA_2	604	610	PF00069	0.345
MOD_PKA_2	62	68	PF00069	0.230
MOD_PKA_2	912	918	PF00069	0.223
MOD_Plk_1	234	240	PF00069	0.355
MOD_Plk_1	283	289	PF00069	0.266
MOD_Plk_1	712	718	PF00069	0.335
MOD_Plk_1	783	789	PF00069	0.670
MOD_Plk_2-3	438	444	PF00069	0.598
MOD_Plk_4	101	107	PF00069	0.302
MOD_Plk_4	1016	1022	PF00069	0.269
MOD_Plk_4	1076	1082	PF00069	0.331
MOD_Plk_4	1142	1148	PF00069	0.355
MOD_Plk_4	131	137	PF00069	0.278
MOD_Plk_4	165	171	PF00069	0.338
MOD_Plk_4	258	264	PF00069	0.284
MOD_Plk_4	396	402	PF00069	0.326
MOD_Plk_4	545	551	PF00069	0.210
MOD_Plk_4	605	611	PF00069	0.320
MOD_Plk_4	76	82	PF00069	0.291
MOD_Plk_4	783	789	PF00069	0.481
MOD_Plk_4	868	874	PF00069	0.308
MOD_Plk_4	928	934	PF00069	0.321
MOD_ProDKin_1	108	114	PF00069	0.378
MOD_ProDKin_1	26	32	PF00069	0.462
MOD_ProDKin_1	294	300	PF00069	0.304
MOD_ProDKin_1	335	341	PF00069	0.257
MOD_ProDKin_1	444	450	PF00069	0.602
MOD_ProDKin_1	470	476	PF00069	0.702
MOD_ProDKin_1	737	743	PF00069	0.530
MOD_ProDKin_1	769	775	PF00069	0.688
MOD_ProDKin_1	820	826	PF00069	0.480
MOD_ProDKin_1	859	865	PF00069	0.352
MOD_ProDKin_1	968	974	PF00069	0.306
MOD_SUMO_rev_2	1005	1013	PF00179	0.281
MOD_SUMO_rev_2	8	17	PF00179	0.345
TRG_DiLeu_BaEn_1	268	273	PF01217	0.353
TRG_DiLeu_BaLyEn_6	1089	1094	PF01217	0.223
TRG_DiLeu_BaLyEn_6	738	743	PF01217	0.644
TRG_DiLeu_BaLyEn_6	865	870	PF01217	0.326
TRG_ENDOCYTIC_2	1041	1044	PF00928	0.352
TRG_ENDOCYTIC_2	1144	1147	PF00928	0.241
TRG_ENDOCYTIC_2	172	175	PF00928	0.357
TRG_ER_diArg_1	1183	1186	PF00400	0.479
TRG_ER_diArg_1	164	166	PF00400	0.426
TRG_ER_diArg_1	480	482	PF00400	0.469
TRG_ER_diArg_1	558	561	PF00400	0.347
TRG_ER_diArg_1	590	593	PF00400	0.281
TRG_ER_diArg_1	873	875	PF00400	0.331
TRG_NES_CRM1_1	347	362	PF08389	0.293
TRG_Pf-PMV_PEXEL_1	1169	1174	PF00026	0.440
TRG_Pf-PMV_PEXEL_1	840	844	PF00026	0.368

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8I8	Leptomonas seymouri	67%	98%
A0A1X0P0Y8	Trypanosomatidae	46%	100%
A0A3S7X6H3	Leishmania donovani	100%	100%
A4H903	Leishmania braziliensis	35%	100%
A4HLF4	Leishmania braziliensis	81%	100%
A4HTF0	Leishmania infantum	31%	100%
E9B3T4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q4Q490	Leishmania major	95%	100%
Q4QED4	Leishmania major	35%	100%
Q95Z93	Leishmania major	24%	100%
Q9NQ11	Homo sapiens	22%	100%
V5BPC6	Trypanosoma cruzi	47%	100%