ATP-binding cassette protein subfamily F, member 3

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-binding cassette sub-family F member 1 - putative

Species:

Leishmania infantum

UniProt:

A4I8P8_LEIIN

TriTrypDb:

LINF_330008900

Length:

668

Annotations

Annotations by Jardim et al.

Transporters, ATP-binding cassette F, member 3 ABCF2

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	yes	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A4I8P8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I8P8

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	13
GO:0003824	catalytic activity	1	1
GO:0005215	transporter activity	1	1
GO:0005488	binding	1	13
GO:0005524	ATP binding	5	13
GO:0015399	primary active transmembrane transporter activity	4	1
GO:0016787	hydrolase activity	2	1
GO:0017076	purine nucleotide binding	4	13
GO:0022804	active transmembrane transporter activity	3	1
GO:0022857	transmembrane transporter activity	2	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	142	146	PF00656	0.452
CLV_C14_Caspase3-7	379	383	PF00656	0.472
CLV_C14_Caspase3-7	537	541	PF00656	0.518
CLV_NRD_NRD_1	18	20	PF00675	0.605
CLV_NRD_NRD_1	198	200	PF00675	0.346
CLV_NRD_NRD_1	21	23	PF00675	0.579
CLV_NRD_NRD_1	222	224	PF00675	0.320
CLV_NRD_NRD_1	269	271	PF00675	0.469
CLV_NRD_NRD_1	365	367	PF00675	0.478
CLV_NRD_NRD_1	484	486	PF00675	0.350

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0H2VBH0	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	35%	100%
A0A0H2VFI8	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	28%	100%
A0A0N0P4L2	Leptomonas seymouri	38%	92%
A0A0N1I593	Leptomonas seymouri	89%	100%
A0A0N1PAH6	Leptomonas seymouri	40%	100%
A0A0S4IYK6	Bodo saltans	48%	100%
A0A0S4JRN6	Bodo saltans	72%	98%
A0A0S4JUD9	Bodo saltans	33%	100%
A0A1X0P0L3	Trypanosomatidae	80%	99%
A0A1X0P688	Trypanosomatidae	39%	100%

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