Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania infantum

UniProt:

A4I8M7_LEIIN

TriTrypDb:

LINF_330006200

Length:

289

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I8M7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I8M7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	193	197	PF00656	0.646
CLV_C14_Caspase3-7	205	209	PF00656	0.486
CLV_NRD_NRD_1	107	109	PF00675	0.773
CLV_NRD_NRD_1	124	126	PF00675	0.519
CLV_NRD_NRD_1	157	159	PF00675	0.570
CLV_NRD_NRD_1	215	217	PF00675	0.696
CLV_NRD_NRD_1	248	250	PF00675	0.692
CLV_NRD_NRD_1	285	287	PF00675	0.566
CLV_NRD_NRD_1	83	85	PF00675	0.687
CLV_PCSK_KEX2_1	124	126	PF00082	0.531
CLV_PCSK_KEX2_1	157	159	PF00082	0.574
CLV_PCSK_KEX2_1	174	176	PF00082	0.610
CLV_PCSK_KEX2_1	217	219	PF00082	0.612
CLV_PCSK_KEX2_1	248	250	PF00082	0.692
CLV_PCSK_KEX2_1	285	287	PF00082	0.566
CLV_PCSK_KEX2_1	83	85	PF00082	0.687
CLV_PCSK_PC1ET2_1	174	176	PF00082	0.510
CLV_PCSK_PC1ET2_1	217	219	PF00082	0.597
CLV_PCSK_SKI1_1	225	229	PF00082	0.587
CLV_PCSK_SKI1_1	271	275	PF00082	0.572
DEG_Nend_UBRbox_1	1	4	PF02207	0.574
DEG_SPOP_SBC_1	86	90	PF00917	0.690
DOC_MAPK_gen_1	171	179	PF00069	0.540
DOC_PP2B_LxvP_1	27	30	PF13499	0.605
DOC_USP7_MATH_1	258	262	PF00917	0.611
DOC_USP7_MATH_1	86	90	PF00917	0.692
DOC_WW_Pin1_4	103	108	PF00397	0.633
DOC_WW_Pin1_4	113	118	PF00397	0.550
DOC_WW_Pin1_4	17	22	PF00397	0.675
DOC_WW_Pin1_4	96	101	PF00397	0.740
LIG_14-3-3_CanoR_1	142	148	PF00244	0.595
LIG_14-3-3_CanoR_1	157	163	PF00244	0.412
LIG_14-3-3_CanoR_1	234	240	PF00244	0.697
LIG_14-3-3_CanoR_1	54	63	PF00244	0.579
LIG_FHA_2	144	150	PF00498	0.531
LIG_FHA_2	191	197	PF00498	0.550
LIG_Rb_LxCxE_1	74	93	PF01857	0.511
LIG_RPA_C_Fungi	146	158	PF08784	0.498
LIG_RPA_C_Fungi	244	256	PF08784	0.636
LIG_SH2_STAT3	145	148	PF00017	0.520
LIG_SH2_STAT5	145	148	PF00017	0.527
LIG_SH3_3	30	36	PF00018	0.653
LIG_SH3_3	40	46	PF00018	0.516
LIG_SH3_3	47	53	PF00018	0.496
LIG_TRAF2_1	146	149	PF00917	0.519
LIG_TRAF2_1	277	280	PF00917	0.652
LIG_TRAF2_1	46	49	PF00917	0.565
LIG_WW_2	50	53	PF00397	0.619
LIG_WW_3	116	120	PF00397	0.656
MOD_CDC14_SPxK_1	106	109	PF00782	0.638
MOD_CDC14_SPxK_1	116	119	PF00782	0.751
MOD_CDK_SPK_2	103	108	PF00069	0.694
MOD_CDK_SPxK_1	103	109	PF00069	0.694
MOD_CDK_SPxK_1	113	119	PF00069	0.553
MOD_CDK_SPxxK_3	96	103	PF00069	0.633
MOD_CK1_1	12	18	PF00069	0.708
MOD_CK1_1	159	165	PF00069	0.504
MOD_CK1_1	223	229	PF00069	0.578
MOD_CK1_1	87	93	PF00069	0.666
MOD_CK2_1	143	149	PF00069	0.525
MOD_CK2_1	258	264	PF00069	0.602
MOD_Cter_Amidation	283	286	PF01082	0.568
MOD_GlcNHglycan	11	14	PF01048	0.767
MOD_GlcNHglycan	225	228	PF01048	0.686
MOD_GlcNHglycan	229	232	PF01048	0.627
MOD_GlcNHglycan	250	253	PF01048	0.762
MOD_GSK3_1	103	110	PF00069	0.638
MOD_GSK3_1	15	22	PF00069	0.719
MOD_GSK3_1	223	230	PF00069	0.739
MOD_GSK3_1	235	242	PF00069	0.609
MOD_GSK3_1	258	265	PF00069	0.664
MOD_GSK3_1	86	93	PF00069	0.714
MOD_NEK2_1	143	148	PF00069	0.499
MOD_NEK2_1	190	195	PF00069	0.642
MOD_NEK2_1	23	28	PF00069	0.782
MOD_NEK2_2	107	112	PF00069	0.639
MOD_PIKK_1	156	162	PF00454	0.499
MOD_PIKK_1	57	63	PF00454	0.625
MOD_PK_1	263	269	PF00069	0.554
MOD_PKA_1	248	254	PF00069	0.700
MOD_PKA_2	107	113	PF00069	0.636
MOD_PKA_2	156	162	PF00069	0.499
MOD_PKA_2	248	254	PF00069	0.700
MOD_PKA_2	262	268	PF00069	0.666
MOD_Plk_1	23	29	PF00069	0.636
MOD_Plk_1	263	269	PF00069	0.637
MOD_Plk_4	198	204	PF00069	0.550
MOD_Plk_4	206	212	PF00069	0.553
MOD_ProDKin_1	103	109	PF00069	0.633
MOD_ProDKin_1	113	119	PF00069	0.553
MOD_ProDKin_1	17	23	PF00069	0.675
MOD_ProDKin_1	96	102	PF00069	0.739
TRG_ENDOCYTIC_2	173	176	PF00928	0.637
TRG_ENDOCYTIC_2	229	232	PF00928	0.662
TRG_ER_diArg_1	111	114	PF00400	0.787
TRG_ER_diArg_1	123	125	PF00400	0.452
TRG_ER_diArg_1	156	158	PF00400	0.561
TRG_Pf-PMV_PEXEL_1	276	280	PF00026	0.610

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5B4	Leptomonas seymouri	44%	99%
A0A3Q8ITS9	Leishmania donovani	98%	95%
A4HL48	Leishmania braziliensis	65%	100%
E9B3I9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%