Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I8I0_LEIIN

TriTrypDb:

LINF_320043200

Length:

200

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I8I0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I8I0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	164	168	PF00656	0.494
CLV_C14_Caspase3-7	79	83	PF00656	0.434
CLV_NRD_NRD_1	109	111	PF00675	0.558
CLV_NRD_NRD_1	59	61	PF00675	0.536
CLV_PCSK_FUR_1	110	114	PF00082	0.383
CLV_PCSK_KEX2_1	109	111	PF00082	0.564
CLV_PCSK_KEX2_1	112	114	PF00082	0.527
CLV_PCSK_KEX2_1	59	61	PF00082	0.536
CLV_PCSK_PC1ET2_1	112	114	PF00082	0.384
CLV_PCSK_SKI1_1	170	174	PF00082	0.517
CLV_PCSK_SKI1_1	177	181	PF00082	0.457
CLV_PCSK_SKI1_1	196	200	PF00082	0.465
CLV_PCSK_SKI1_1	67	71	PF00082	0.509
CLV_Separin_Metazoa	106	110	PF03568	0.516
CLV_Separin_Metazoa	68	72	PF03568	0.520
DEG_APCC_DBOX_1	169	177	PF00400	0.569
DEG_APCC_DBOX_1	66	74	PF00400	0.520
DOC_MAPK_gen_1	32	41	PF00069	0.595
DOC_MAPK_MEF2A_6	71	78	PF00069	0.487
DOC_MAPK_NFAT4_5	71	79	PF00069	0.488
DOC_PP2B_LxvP_1	144	147	PF13499	0.589
DOC_USP7_MATH_1	152	156	PF00917	0.634
DOC_WW_Pin1_4	165	170	PF00397	0.487
LIG_14-3-3_CanoR_1	50	58	PF00244	0.406
LIG_BIR_II_1	1	5	PF00653	0.624
LIG_FHA_1	141	147	PF00498	0.573
LIG_FHA_1	32	38	PF00498	0.552
LIG_FHA_1	98	104	PF00498	0.491
LIG_FHA_2	157	163	PF00498	0.582
LIG_FHA_2	63	69	PF00498	0.501
LIG_FHA_2	77	83	PF00498	0.402
LIG_NRBOX	69	75	PF00104	0.529
LIG_PDZ_Class_2	195	200	PF00595	0.476
LIG_SH2_STAT5	22	25	PF00017	0.537
LIG_TRAF2_1	40	43	PF00917	0.456
MOD_CDK_SPK_2	165	170	PF00069	0.460
MOD_CK1_1	168	174	PF00069	0.501
MOD_CK1_1	2	8	PF00069	0.658
MOD_CK1_1	9	15	PF00069	0.587
MOD_CK2_1	125	131	PF00069	0.458
MOD_CK2_1	156	162	PF00069	0.645
MOD_CK2_1	168	174	PF00069	0.661
MOD_CK2_1	62	68	PF00069	0.503
MOD_GlcNHglycan	10	14	PF01048	0.597
MOD_GlcNHglycan	100	103	PF01048	0.439
MOD_GlcNHglycan	154	157	PF01048	0.644
MOD_GlcNHglycan	170	173	PF01048	0.390
MOD_GlcNHglycan	90	93	PF01048	0.653
MOD_GSK3_1	152	159	PF00069	0.625
MOD_GSK3_1	161	168	PF00069	0.502
MOD_GSK3_1	190	197	PF00069	0.529
MOD_GSK3_1	2	9	PF00069	0.656
MOD_GSK3_1	76	83	PF00069	0.593
MOD_GSK3_1	84	91	PF00069	0.668
MOD_PIKK_1	116	122	PF00454	0.505
MOD_PK_1	125	131	PF00069	0.482
MOD_PKA_2	31	37	PF00069	0.446
MOD_PKA_2	84	90	PF00069	0.527
MOD_Plk_1	187	193	PF00069	0.437
MOD_Plk_4	156	162	PF00069	0.587
MOD_Plk_4	187	193	PF00069	0.437
MOD_ProDKin_1	165	171	PF00069	0.483
MOD_SUMO_for_1	179	182	PF00179	0.441
MOD_SUMO_rev_2	174	181	PF00179	0.502
TRG_ER_diArg_1	108	110	PF00400	0.563
TRG_ER_diArg_1	58	60	PF00400	0.495
TRG_NES_CRM1_1	68	82	PF08389	0.536

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HVP8	Leptomonas seymouri	34%	97%
A0A3Q8ILP4	Leishmania donovani	100%	100%
A4HKZ9	Leishmania braziliensis	62%	100%
E9B3E0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q4R2	Leishmania major	90%	100%