Membrane-associated protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I8H9_LEIIN

TriTrypDb:

LINF_320043100

Length:

117


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	8
GO:0110165	cellular anatomical entity	1	8

A4I8H9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I8H9


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	8	12	PF00656	0.670
CLV_NRD_NRD_1	85	87	PF00675	0.418
CLV_PCSK_KEX2_1	84	86	PF00082	0.430
DOC_CYCLIN_yCln2_LP_2	60	66	PF00134	0.344
DOC_PP2B_LxvP_1	60	63	PF13499	0.325
DOC_PP2B_PxIxI_1	1	7	PF00149	0.601
DOC_USP7_MATH_1	66	70	PF00917	0.446
DOC_USP7_MATH_1	9	13	PF00917	0.581
LIG_14-3-3_CanoR_1	85	95	PF00244	0.718
LIG_Actin_WH2_2	67	82	PF00022	0.454
LIG_BRCT_BRCA1_1	67	71	PF00533	0.485
LIG_FHA_1	1	7	PF00498	0.601
LIG_FHA_1	20	26	PF00498	0.699
LIG_FHA_1	55	61	PF00498	0.304
LIG_IRF3_LxIS_1	44	49	PF10401	0.444
LIG_LIR_Gen_1	27	37	PF02991	0.496
LIG_LIR_Gen_1	41	50	PF02991	0.444
LIG_LIR_Gen_1	68	79	PF02991	0.412
LIG_LIR_Nem_3	27	32	PF02991	0.558
LIG_LIR_Nem_3	41	46	PF02991	0.444
LIG_LIR_Nem_3	68	74	PF02991	0.427
LIG_SH2_PTP2	43	46	PF00017	0.369
LIG_SH2_STAP1	96	100	PF00017	0.721
LIG_SH2_STAT5	43	46	PF00017	0.344
LIG_SH3_3	106	112	PF00018	0.726
LIG_SUMO_SIM_par_1	2	8	PF11976	0.597
LIG_SUMO_SIM_par_1	35	41	PF11976	0.352
MOD_CK1_1	12	18	PF00069	0.597
MOD_CK1_1	5	11	PF00069	0.732
MOD_CK1_1	56	62	PF00069	0.275
MOD_GlcNHglycan	11	14	PF01048	0.432
MOD_GlcNHglycan	26	29	PF01048	0.432
MOD_GlcNHglycan	48	51	PF01048	0.548
MOD_GlcNHglycan	60	63	PF01048	0.370
MOD_GlcNHglycan	7	10	PF01048	0.526
MOD_GSK3_1	38	45	PF00069	0.418
MOD_GSK3_1	5	12	PF00069	0.609
MOD_GSK3_1	54	61	PF00069	0.342
MOD_NEK2_1	46	51	PF00069	0.433
MOD_NEK2_2	66	71	PF00069	0.388
MOD_PIKK_1	19	25	PF00454	0.683
MOD_PIKK_1	86	92	PF00454	0.717
MOD_PKB_1	84	92	PF00069	0.714
MOD_Plk_4	38	44	PF00069	0.441
MOD_Plk_4	66	72	PF00069	0.410
MOD_Plk_4	74	80	PF00069	0.377
TRG_ENDOCYTIC_2	43	46	PF00928	0.344
TRG_ER_diArg_1	84	86	PF00400	0.620


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBG0	Leptomonas seymouri	61%	96%
A0A1X0NRX6	Trypanosomatidae	38%	98%
A0A3R7LD90	Trypanosoma rangeli	32%	98%
A0A3S7X638	Leishmania donovani	99%	100%
E9AIV3	Leishmania braziliensis	79%	100%
E9B3D9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	96%
Q4Q4R3	Leishmania major	88%	100%
V5DMF6	Trypanosoma cruzi	34%	98%