LeishMANIAdb
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Dihydrolipoyl dehydrogenase

Quick info Annotations Function or PPIs Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Dihydrolipoyl dehydrogenase
Gene product:
dihydrolipoamide dehydrogenase - putative
Species:
Leishmania infantum
UniProt:
A4I8F6_LEIIN
TriTrypDb:
LINF_320040600
Length:
476

Annotations

Annotations by Jardim et al.

Pyruvate metabolism, Dihydrolipoyl dehydrogenase E2

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. yes yes: 2
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 20
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 6
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 12
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0005739 mitochondrion 5 1
GO:0032991 protein-containing complex 1 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0045239 tricarboxylic acid cycle enzyme complex 3 1
GO:0045240 dihydrolipoyl dehydrogenase complex 4 1
GO:0045252 oxoglutarate dehydrogenase complex 4 1
GO:0110165 cellular anatomical entity 1 1
GO:1902494 catalytic complex 2 1
GO:1990204 oxidoreductase complex 3 1
GO:1990234 transferase complex 3 1

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

A4I8F6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I8F6

Function

Biological processes
Term Name Level Count
GO:0009987 cellular process 1 12
GO:0019725 cellular homeostasis 2 12
GO:0042592 homeostatic process 3 12
GO:0045454 cell redox homeostasis 3 12
GO:0050789 regulation of biological process 2 12
GO:0050794 regulation of cellular process 3 12
GO:0065007 biological regulation 1 12
GO:0065008 regulation of biological quality 2 12
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 12
GO:0003824 catalytic activity 1 12
GO:0004148 dihydrolipoyl dehydrogenase activity 5 12
GO:0005488 binding 1 12
GO:0016491 oxidoreductase activity 2 12
GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3 12
GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 4 12
GO:0036094 small molecule binding 2 12
GO:0043167 ion binding 2 12
GO:0043168 anion binding 3 12
GO:0050660 flavin adenine dinucleotide binding 4 12
GO:0097159 organic cyclic compound binding 2 12
GO:1901265 nucleoside phosphate binding 3 12
GO:1901363 heterocyclic compound binding 2 12

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 263 267 PF00656 0.350
CLV_NRD_NRD_1 283 285 PF00675 0.301
CLV_NRD_NRD_1 3 5 PF00675 0.515
CLV_PCSK_KEX2_1 283 285 PF00082 0.329
CLV_PCSK_KEX2_1 3 5 PF00082 0.515
CLV_PCSK_KEX2_1 379 381 PF00082 0.363
CLV_PCSK_KEX2_1 42 44 PF00082 0.293
CLV_PCSK_PC1ET2_1 379 381 PF00082 0.363
CLV_PCSK_PC1ET2_1 42 44 PF00082 0.293
CLV_PCSK_SKI1_1 228 232 PF00082 0.414
CLV_PCSK_SKI1_1 241 245 PF00082 0.288
CLV_PCSK_SKI1_1 408 412 PF00082 0.350
CLV_PCSK_SKI1_1 43 47 PF00082 0.309
CLV_PCSK_SKI1_1 59 63 PF00082 0.110
CLV_PCSK_SKI1_1 99 103 PF00082 0.309
DEG_Nend_Nbox_1 1 3 PF02207 0.522
DEG_SPOP_SBC_1 170 174 PF00917 0.293
DOC_CYCLIN_RxL_1 56 65 PF00134 0.293
DOC_MAPK_gen_1 413 423 PF00069 0.353
DOC_MAPK_MEF2A_6 414 423 PF00069 0.350
DOC_MAPK_RevD_3 132 148 PF00069 0.328
DOC_PP4_FxxP_1 126 129 PF00568 0.348
DOC_USP7_MATH_1 152 156 PF00917 0.293
DOC_USP7_MATH_1 224 228 PF00917 0.414
DOC_USP7_MATH_1 456 460 PF00917 0.301
LIG_Actin_WH2_2 21 38 PF00022 0.310
LIG_APCC_ABBA_1 162 167 PF00400 0.293
LIG_FHA_1 103 109 PF00498 0.168
LIG_FHA_1 129 135 PF00498 0.361
LIG_FHA_1 172 178 PF00498 0.298
LIG_FHA_1 229 235 PF00498 0.318
LIG_FHA_1 244 250 PF00498 0.289
LIG_FHA_1 257 263 PF00498 0.293
LIG_FHA_1 285 291 PF00498 0.307
LIG_FHA_1 35 41 PF00498 0.306
LIG_FHA_1 413 419 PF00498 0.293
LIG_FHA_1 85 91 PF00498 0.343
LIG_FHA_2 151 157 PF00498 0.293
LIG_FHA_2 208 214 PF00498 0.280
LIG_FHA_2 220 226 PF00498 0.280
LIG_FHA_2 361 367 PF00498 0.293
LIG_FHA_2 455 461 PF00498 0.293
LIG_LIR_Apic_2 123 129 PF02991 0.348
LIG_LIR_Gen_1 200 209 PF02991 0.293
LIG_LIR_Gen_1 300 310 PF02991 0.309
LIG_LIR_Gen_1 403 410 PF02991 0.293
LIG_LIR_Nem_3 159 165 PF02991 0.414
LIG_LIR_Nem_3 200 205 PF02991 0.293
LIG_LIR_Nem_3 300 306 PF02991 0.309
LIG_LIR_Nem_3 403 409 PF02991 0.293
LIG_LRP6_Inhibitor_1 127 133 PF00058 0.440
LIG_PDZ_Class_2 471 476 PF00595 0.388
LIG_SH2_CRK 354 358 PF00017 0.365
LIG_SH2_GRB2like 362 365 PF00017 0.414
LIG_SH2_NCK_1 354 358 PF00017 0.369
LIG_SH2_NCK_1 362 366 PF00017 0.288
LIG_SH2_SRC 318 321 PF00017 0.309
LIG_SH2_STAP1 12 16 PF00017 0.309
LIG_SH2_STAT5 110 113 PF00017 0.309
LIG_SH2_STAT5 24 27 PF00017 0.275
LIG_SH2_STAT5 362 365 PF00017 0.293
LIG_SH3_3 158 164 PF00018 0.293
LIG_SUMO_SIM_anti_2 13 18 PF11976 0.285
LIG_SUMO_SIM_anti_2 208 213 PF11976 0.313
LIG_SUMO_SIM_par_1 256 264 PF11976 0.329
LIG_TRAF2_1 334 337 PF00917 0.414
LIG_TYR_ITIM 352 357 PF00017 0.365
MOD_CK1_1 146 152 PF00069 0.333
MOD_CK1_1 155 161 PF00069 0.248
MOD_CK1_1 256 262 PF00069 0.431
MOD_CK1_1 392 398 PF00069 0.378
MOD_CK2_1 150 156 PF00069 0.293
MOD_CK2_1 207 213 PF00069 0.283
MOD_CK2_1 360 366 PF00069 0.293
MOD_CK2_1 454 460 PF00069 0.293
MOD_Cter_Amidation 281 284 PF01082 0.335
MOD_GlcNHglycan 249 252 PF01048 0.305
MOD_GlcNHglycan 391 394 PF01048 0.378
MOD_GlcNHglycan 89 93 PF01048 0.383
MOD_GSK3_1 146 153 PF00069 0.293
MOD_GSK3_1 224 231 PF00069 0.414
MOD_GSK3_1 243 250 PF00069 0.305
MOD_GSK3_1 408 415 PF00069 0.350
MOD_GSK3_1 8 15 PF00069 0.489
MOD_GSK3_1 84 91 PF00069 0.393
MOD_N-GLC_1 253 258 PF02516 0.422
MOD_N-GLC_1 84 89 PF02516 0.435
MOD_NEK2_1 171 176 PF00069 0.298
MOD_NEK2_1 243 248 PF00069 0.296
MOD_NEK2_1 277 282 PF00069 0.307
MOD_NEK2_1 448 453 PF00069 0.324
MOD_NEK2_1 46 51 PF00069 0.306
MOD_NEK2_1 470 475 PF00069 0.380
MOD_NEK2_1 62 67 PF00069 0.249
MOD_NEK2_1 88 93 PF00069 0.393
MOD_Plk_1 12 18 PF00069 0.414
MOD_Plk_1 140 146 PF00069 0.400
MOD_Plk_1 207 213 PF00069 0.328
MOD_Plk_1 84 90 PF00069 0.440
MOD_Plk_2-3 84 90 PF00069 0.328
MOD_Plk_4 115 121 PF00069 0.273
MOD_Plk_4 12 18 PF00069 0.392
MOD_Plk_4 122 128 PF00069 0.292
MOD_Plk_4 146 152 PF00069 0.293
MOD_Plk_4 197 203 PF00069 0.318
MOD_Plk_4 207 213 PF00069 0.293
MOD_SUMO_for_1 235 238 PF00179 0.305
MOD_SUMO_rev_2 141 149 PF00179 0.313
TRG_DiLeu_BaEn_1 273 278 PF01217 0.414
TRG_ENDOCYTIC_2 354 357 PF00928 0.366
TRG_ER_diArg_1 2 4 PF00400 0.517
TRG_ER_diArg_1 283 285 PF00400 0.279
TRG_NLS_MonoExtC_3 377 383 PF00514 0.440
TRG_Pf-PMV_PEXEL_1 417 422 PF00026 0.414

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P491 Leptomonas seymouri 90% 100%
A0A0N1HUA4 Leptomonas seymouri 27% 84%
A0A0N1I1H2 Leptomonas seymouri 29% 97%
A0A0N1IHT7 Leptomonas seymouri 29% 94%
A0A0N1IIN8 Leptomonas seymouri 26% 91%
A0A0S4J6A3 Bodo saltans 30% 96%
A0A0S4JDA8 Bodo saltans 72% 100%
A0A0S4KLJ6 Bodo saltans 27% 76%
A0A1X0NJ18 Trypanosomatidae 26% 74%
A0A1X0NK15 Trypanosomatidae 28% 81%
A0A1X0NRW2 Trypanosomatidae 78% 100%
A0A1X0NZX1 Trypanosomatidae 27% 94%
A0A1X0P0G9 Trypanosomatidae 29% 97%
A0A3Q8IDT8 Leishmania donovani 30% 94%
A0A3Q8IF30 Leishmania donovani 26% 87%
A0A3Q8ITM5 Leishmania donovani 100% 100%
A0A3R7KY91 Trypanosoma rangeli 75% 100%
A0A3R7NB58 Trypanosoma rangeli 28% 97%
A0A3R7NSH5 Trypanosoma rangeli 27% 94%
A0A3S7WP12 Leishmania donovani 28% 97%
A0A3S7X4X4 Leishmania donovani 25% 76%
A0A422NPA5 Trypanosoma rangeli 23% 77%
A0A422NPB5 Trypanosoma rangeli 28% 81%
A0LY71 Gramella forsetii (strain KT0803) 24% 100%
A1AIE2 Escherichia coli O1:K1 / APEC 30% 100%
A1JI37 Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) 31% 100%
A1KM51 Mycobacterium bovis (strain BCG / Pasteur 1173P2) 34% 100%
A1U1Y5 Marinobacter nauticus (strain ATCC 700491 / DSM 11845 / VT8) 31% 100%
A2TIL1 Callithrix jacchus 26% 91%
A4H480 Leishmania braziliensis 28% 100%
A4HIY7 Leishmania braziliensis 30% 100%
A4HJQ2 Leishmania braziliensis 27% 100%
A4HKX6 Leishmania braziliensis 92% 100%
A4HSF7 Leishmania infantum 28% 100%
A4I4P1 Leishmania infantum 30% 94%
A4I769 Leishmania infantum 25% 100%
A4TRG4 Yersinia pestis (strain Pestoides F) 31% 100%
A4VMU6 Pseudomonas stutzeri (strain A1501) 30% 100%
A4WG49 Enterobacter sp. (strain 638) 31% 100%
A4X398 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) 24% 100%
A4XSQ1 Pseudomonas mendocina (strain ymp) 31% 100%
A4YER6 Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) 24% 100%
A5F4K5 Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395) 31% 100%
A5U665 Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) 34% 100%
A5W6F5 Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1) 32% 100%
A6TGE6 Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) 31% 100%
A6V3A6 Pseudomonas aeruginosa (strain PA7) 30% 100%
A6VW16 Marinomonas sp. (strain MWYL1) 32% 100%
A7FD10 Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) 31% 100%
A7ZUI2 Escherichia coli O139:H28 (strain E24377A / ETEC) 30% 100%
A8A770 Escherichia coli O9:H4 (strain HS) 30% 100%
A8AKW0 Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696) 30% 100%
A8GL77 Serratia proteamaculans (strain 568) 30% 100%
A8MS68 Arabidopsis thaliana 35% 76%
A9N0H2 Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) 31% 100%
A9R6N5 Yersinia pestis bv. Antiqua (strain Angola) 31% 100%
B0KH90 Pseudomonas putida (strain GB-1) 32% 100%
B1IVB6 Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks) 30% 100%
B1J606 Pseudomonas putida (strain W619) 32% 100%
B1JQ50 Yersinia pseudotuberculosis serotype O:3 (strain YPIII) 31% 100%
B1LNS2 Escherichia coli (strain SMS-3-5 / SECEC) 30% 100%
B1MX70 Leuconostoc citreum (strain KM20) 21% 100%
B1XBX3 Escherichia coli (strain K12 / DH10B) 30% 100%
B2JZF3 Yersinia pseudotuberculosis serotype IB (strain PB1/+) 31% 100%
B2TWF7 Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) 30% 100%
B2VGA0 Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99) 32% 100%
B3EKW5 Chlorobium phaeobacteroides (strain BS1) 25% 100%
B3QPZ8 Chlorobaculum parvum (strain DSM 263 / NCIMB 8327) 24% 100%
B3QXE1 Chloroherpeton thalassium (strain ATCC 35110 / GB-78) 24% 100%
B4F1H1 Proteus mirabilis (strain HI4320) 31% 100%
B4S9F8 Prosthecochloris aestuarii (strain DSM 271 / SK 413) 25% 100%
B4U394 Streptococcus equi subsp. zooepidemicus (strain MGCS10565) 24% 100%
B5BJN6 Salmonella paratyphi A (strain AKU_12601) 31% 100%
B5QXQ7 Salmonella enteritidis PT4 (strain P125109) 31% 100%
B5REZ6 Salmonella gallinarum (strain 287/91 / NCTC 13346) 31% 100%
B5XZ14 Klebsiella pneumoniae (strain 342) 30% 100%
B5Z064 Escherichia coli O157:H7 (strain EC4115 / EHEC) 30% 100%
B6I5I0 Escherichia coli (strain SE11) 30% 100%
B7LA64 Escherichia coli (strain 55989 / EAEC) 30% 100%
B7LUN3 Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73) 30% 100%
B7M718 Escherichia coli O8 (strain IAI1) 30% 100%
B7MIA0 Escherichia coli O45:K1 (strain S88 / ExPEC) 30% 100%
B7MR55 Escherichia coli O81 (strain ED1a) 30% 100%
B7NFR2 Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) 30% 100%
B7NU38 Escherichia coli O7:K1 (strain IAI39 / ExPEC) 30% 100%
B7UNU0 Escherichia coli O127:H6 (strain E2348/69 / EPEC) 30% 100%
B7UZU5 Pseudomonas aeruginosa (strain LESB58) 30% 100%
B7VM91 Vibrio atlanticus (strain LGP32) 31% 100%
B9A1H3 Emiliania huxleyi 26% 96%
C0Q478 Salmonella paratyphi C (strain RKS4594) 31% 100%
C1AFH2 Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019) 34% 100%
C1DR10 Azotobacter vinelandii (strain DJ / ATCC BAA-1303) 32% 100%
C3K4W1 Pseudomonas fluorescens (strain SBW25) 31% 100%
C3LPZ2 Vibrio cholerae serotype O1 (strain M66-2) 31% 100%
C4K3I8 Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT) 29% 100%
C5A0R1 Escherichia coli (strain K12 / MC4100 / BW2952) 30% 100%
C9ZLC8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 94%
C9ZMF4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 79%
C9ZWN2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 26% 87%
D0A4H8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 97%
D0AAR5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 77% 100%
D0VWY5 Marichromatium gracile 30% 100%
E9AE44 Leishmania major 30% 100%
E9AHL8 Leishmania infantum 26% 87%
E9AKE1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 100%
E9ALP1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 29% 100%
E9B263 Leishmania mexicana (strain MHOM/GT/2001/U1103) 26% 100%
E9B264 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 100%
E9B3B4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
F4JLP5 Arabidopsis thaliana 34% 84%
G0SB20 Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) 53% 94%
O00087 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 55% 93%
O04955 Brassica rapa subsp. pekinensis 28% 95%
O05139 Pseudomonas fluorescens 31% 100%
O05204 Staphylococcus aureus (strain NCTC 8325 / PS 47) 28% 94%
O05940 Rhizobium etli (strain CFN 42 / ATCC 51251) 40% 99%
O08749 Mus musculus 51% 94%
O15770 Plasmodium falciparum (isolate 3D7) 28% 87%
O17953 Caenorhabditis elegans 55% 96%
O18480 Manduca sexta 53% 96%
O32823 Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) 25% 100%
O34324 Bacillus subtilis (strain 168) 34% 100%
O50286 Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) 42% 100%
O50311 Chlorobaculum parvum (strain DSM 263 / NCIMB 8327) 39% 100%
O62768 Bos taurus 28% 95%
O84561 Chlamydia trachomatis (strain D/UW-3/Cx) 39% 100%
O89049 Rattus norvegicus 28% 95%
P00390 Homo sapiens 27% 91%
P00392 Pseudomonas aeruginosa 31% 85%
P06715 Escherichia coli (strain K12) 30% 100%
P08332 Shigella flexneri 30% 84%
P09063 Pseudomonas putida 39% 100%
P09622 Homo sapiens 53% 94%
P09623 Sus scrofa 53% 94%
P09624 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 55% 95%
P0A0E4 Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) 34% 87%
P0A0E5 Staphylococcus aureus 34% 87%
P0A0E6 Staphylococcus aureus (strain Mu50 / ATCC 700699) 44% 100%
P0A0E7 Staphylococcus aureus (strain MW2) 44% 100%
P0A0E8 Staphylococcus aureus 44% 100%
P0A9P0 Escherichia coli (strain K12) 41% 100%
P0A9P1 Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) 41% 100%
P0A9P2 Escherichia coli O157:H7 41% 100%
P0A9P3 Shigella flexneri 41% 100%
P11959 Geobacillus stearothermophilus 45% 100%
P13110 Trypanosoma congolense 28% 97%
P14218 Pseudomonas fluorescens 49% 100%
P16171 Bacillus cereus 36% 75%
P17239 Acidithiobacillus ferrooxidans 29% 87%
P18925 Azotobacter vinelandii 49% 100%
P21880 Bacillus subtilis (strain 168) 45% 100%
P23189 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 31% 100%
P27306 Escherichia coli (strain K12) 30% 100%
P27456 Pisum sativum 28% 86%
P28593 Trypanosoma cruzi 27% 97%
P30341 Streptomyces lividans 30% 100%
P30635 Caenorhabditis elegans 27% 95%
P31023 Pisum sativum 58% 95%
P31046 Pseudomonas putida 51% 100%
P31052 Pseudomonas putida 50% 100%
P35484 Acholeplasma laidlawii 38% 100%
P37062 Enterococcus faecalis (strain ATCC 700802 / V583) 25% 100%
P39040 Crithidia fasciculata 28% 97%
P39050 Leishmania donovani 27% 97%
P39051 Trypanosoma brucei brucei 29% 97%
P41921 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 30% 99%
P42770 Arabidopsis thaliana 27% 84%
P43783 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) 29% 100%
P43784 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) 41% 100%
P47513 Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) 37% 100%
P47791 Mus musculus 28% 95%
P48638 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) 28% 100%
P48639 Burkholderia cepacia 28% 100%
P48640 Glycine max 27% 88%
P48641 Arabidopsis thaliana 27% 95%
P48642 Oryza sativa subsp. japonica 27% 96%
P49819 Canis lupus familiaris 52% 94%
P50529 Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) 31% 100%
P50970 Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 38% 100%
P52992 Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) 49% 100%
P54533 Bacillus subtilis (strain 168) 41% 100%
P57112 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 30% 100%
P57303 Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) 35% 100%
P61076 Plasmodium falciparum (isolate 3D7) 27% 77%
P66005 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) 41% 100%
P66007 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) 34% 100%
P66008 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 31% 100%
P66009 Salmonella typhi 31% 100%
P66012 Staphylococcus aureus (strain Mu50 / ATCC 700699) 28% 94%
P66013 Staphylococcus aureus (strain MW2) 28% 94%
P70619 Rattus norvegicus 25% 100%
P72740 Synechocystis sp. (strain PCC 6803 / Kazusa) 35% 100%
P75393 Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) 37% 100%
P77212 Escherichia coli (strain K12) 28% 100%
P78965 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 29% 100%
P80461 Nicotiana tabacum 27% 85%
P85207 Thermus scotoductus (strain ATCC 700910 / SA-01) 46% 100%
P90597 Trypanosoma cruzi 76% 100%
P91938 Drosophila melanogaster 28% 80%
P94188 Alcaligenes sp. 30% 85%
P94284 Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) 27% 100%
P94702 Enterobacter agglomerans 30% 85%
P95596 Rhodobacter capsulatus 54% 100%
P99084 Staphylococcus aureus (strain N315) 44% 100%
P99118 Staphylococcus aureus (strain N315) 28% 94%
P9WHH0 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 26% 100%
P9WHH1 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 26% 100%
P9WHH2 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 26% 100%
P9WHH3 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 26% 100%
P9WHH4 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 34% 100%
P9WHH5 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 34% 100%
P9WHH6 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 25% 97%
P9WHH7 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 25% 97%
P9WHH8 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 41% 100%
P9WHH9 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 41% 100%
Q02733 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 34% 95%
Q02PF5 Pseudomonas aeruginosa (strain UCBPP-PA14) 30% 100%
Q04829 Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) 41% 100%
Q04933 Trypanosoma brucei brucei 75% 99%
Q0TA96 Escherichia coli O6:K15:H31 (strain 536 / UPEC) 30% 100%
Q16881 Homo sapiens 27% 73%
Q17745 Caenorhabditis elegans 25% 71%
Q1CBU5 Yersinia pestis bv. Antiqua (strain Antiqua) 31% 100%
Q1CNP4 Yersinia pestis bv. Antiqua (strain Nepal516) 31% 100%
Q1I7F0 Pseudomonas entomophila (strain L48) 32% 100%
Q1QX78 Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) 30% 100%
Q1R3U7 Escherichia coli (strain UTI89 / UPEC) 30% 100%
Q1RHV1 Rickettsia bellii (strain RML369-C) 23% 100%
Q25861 Plasmodium falciparum (isolate FCH-5) 27% 88%
Q2NQZ3 Sodalis glossinidius (strain morsitans) 30% 100%
Q2SIP2 Hahella chejuensis (strain KCTC 2396) 31% 100%
Q3AS18 Chlorobium chlorochromatii (strain CaD3) 25% 100%
Q3K9F5 Pseudomonas fluorescens (strain Pf0-1) 32% 100%
Q41219 Glycine max 56% 91%
Q43154 Spinacia oleracea 28% 97%
Q43621 Pisum sativum 27% 96%
Q48A14 Colwellia psychrerythraea (strain 34H / ATCC BAA-681) 31% 100%
Q48KI8 Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6) 31% 100%
Q4KFA6 Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) 32% 100%
Q4Q4U1 Leishmania major 99% 100%
Q4Q5Z6 Leishmania major 26% 100%
Q4Q5Z7 Leishmania major 26% 100%
Q4QJG7 Leishmania major 28% 100%
Q4ZV77 Pseudomonas syringae pv. syringae (strain B728a) 31% 100%
Q50068 Mycobacterium leprae (strain TN) 39% 100%
Q51772 Pseudomonas fluorescens 31% 87%
Q52109 Acinetobacter calcoaceticus 31% 85%
Q54465 Shewanella putrefaciens 33% 85%
Q54EW8 Dictyostelium discoideum 54% 98%
Q54UU8 Dictyostelium discoideum 25% 100%
Q56839 Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) 23% 91%
Q57H91 Salmonella choleraesuis (strain SC-B67) 31% 100%
Q58065 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) 26% 100%
Q5E212 Aliivibrio fischeri (strain ATCC 700601 / ES114) 32% 100%
Q5HGY8 Staphylococcus aureus (strain COL) 44% 100%
Q5HIR6 Staphylococcus aureus (strain COL) 28% 94%
Q5HRY2 Staphylococcus epidermidis (strain ATCC 35984 / RP62A) 25% 94%
Q5JGP4 Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) 25% 100%
Q5NVA2 Pongo abelii 27% 95%
Q5PK71 Salmonella paratyphi A (strain ATCC 9150 / SARB42) 31% 100%
Q5R4B1 Pongo abelii 52% 94%
Q5UWH2 Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) 38% 100%
Q5UYG6 Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) 42% 100%
Q5XC60 Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394) 27% 100%
Q60151 Streptococcus thermophilus 29% 100%
Q60HG3 Macaca fascicularis 52% 94%
Q66G61 Yersinia pseudotuberculosis serotype I (strain IP32953) 31% 100%
Q6BPI1 Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) 27% 97%
Q6C5H4 Yarrowia lipolytica (strain CLIB 122 / E 150) 31% 100%
Q6CZB1 Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) 32% 100%
Q6FRV2 Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) 30% 100%
Q6GAB8 Staphylococcus aureus (strain MSSA476) 44% 100%
Q6GC92 Staphylococcus aureus (strain MSSA476) 28% 94%
Q6GHY9 Staphylococcus aureus (strain MRSA252) 44% 100%
Q6GJR8 Staphylococcus aureus (strain MRSA252) 28% 94%
Q6HA23 Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) 29% 98%
Q6LLT9 Photobacterium profundum (strain SS9) 31% 100%
Q6P6R2 Rattus norvegicus 52% 94%
Q74ZK4 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) 28% 99%
Q7MBG9 Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) 31% 100%
Q7MQ83 Vibrio vulnificus (strain YJ016) 31% 100%
Q811C4 Mesocricetus auratus 53% 99%
Q83MI1 Shigella flexneri 31% 100%
Q86VQ6 Homo sapiens 27% 74%
Q873E8 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 28% 100%
Q87KN5 Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) 30% 100%
Q884I6 Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000) 31% 100%
Q88KY8 Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) 32% 100%
Q89AQ8 Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) 36% 100%
Q8CIZ7 Cricetulus griseus 52% 94%
Q8CMQ1 Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) 25% 94%
Q8DD46 Vibrio vulnificus (strain CMCP6) 31% 100%
Q8DUN5 Streptococcus mutans serotype c (strain ATCC 700610 / UA159) 25% 100%
Q8EWR4 Malacoplasma penetrans (strain HF-2) 23% 100%
Q8FB93 Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) 30% 100%
Q8K9T7 Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) 37% 100%
Q8KCW2 Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) 41% 100%
Q8NTE1 Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) 41% 100%
Q8T137 Dictyostelium discoideum 27% 100%
Q8X727 Escherichia coli O157:H7 30% 100%
Q8ZA97 Yersinia pestis 31% 100%
Q928B5 Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262) 25% 100%
Q93379 Caenorhabditis elegans 27% 100%
Q94655 Plasmodium falciparum (isolate K1 / Thailand) 28% 95%
Q99MD6 Mus musculus 28% 73%
Q9HN74 Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) 41% 100%
Q9HUY1 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 48% 100%
Q9I1L9 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 38% 100%
Q9I3D1 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 49% 100%
Q9JLT4 Mus musculus 30% 91%
Q9JMH6 Mus musculus 28% 78%
Q9KPF6 Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) 42% 100%
Q9M5K2 Arabidopsis thaliana 59% 94%
Q9M5K3 Arabidopsis thaliana 59% 94%
Q9MYY8 Sus scrofa 27% 95%
Q9N2I8 Bos taurus 28% 93%
Q9NNW7 Homo sapiens 28% 91%
Q9PJI3 Chlamydia muridarum (strain MoPn / Nigg) 39% 100%
Q9SPB1 Vigna unguiculata 56% 91%
Q9UYU5 Pyrococcus abyssi (strain GE5 / Orsay) 25% 100%
Q9VNT5 Drosophila melanogaster 26% 92%
Q9XBQ9 Azotobacter vinelandii 32% 100%
Q9Z0J5 Rattus norvegicus 30% 90%
Q9Z773 Chlamydia pneumoniae 39% 100%
V5AJG2 Trypanosoma cruzi 28% 97%
V5B6P6 Trypanosoma cruzi 28% 86%
V5BB90 Trypanosoma cruzi 25% 87%
V5BDX2 Trypanosoma cruzi 28% 93%
V5BVJ1 Trypanosoma cruzi 77% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS