CHCH domain-containing protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I880_LEIIN

TriTrypDb:

LINF_320032800

Length:

132

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I880

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I880

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	69	71	PF00675	0.576
CLV_PCSK_KEX2_1	69	71	PF00082	0.496
CLV_PCSK_SKI1_1	25	29	PF00082	0.568
CLV_PCSK_SKI1_1	62	66	PF00082	0.558
DOC_CKS1_1	72	77	PF01111	0.472
DOC_USP7_UBL2_3	62	66	PF12436	0.558
DOC_WW_Pin1_4	7	12	PF00397	0.730
DOC_WW_Pin1_4	71	76	PF00397	0.495
LIG_14-3-3_CanoR_1	48	56	PF00244	0.618
LIG_14-3-3_CanoR_1	69	73	PF00244	0.566
LIG_BIR_II_1	1	5	PF00653	0.655
LIG_BRCT_BRCA1_1	111	115	PF00533	0.405
LIG_LIR_Apic_2	71	75	PF02991	0.465
LIG_LIR_Nem_3	29	33	PF02991	0.626
LIG_LIR_Nem_3	63	68	PF02991	0.554
LIG_Pex14_1	72	76	PF04695	0.469
MOD_CK1_1	71	77	PF00069	0.503
MOD_GlcNHglycan	11	14	PF01048	0.657
MOD_GlcNHglycan	59	62	PF01048	0.639
MOD_N-GLC_1	2	7	PF02516	0.623
MOD_NEK2_1	115	120	PF00069	0.356
MOD_PIKK_1	88	94	PF00454	0.511
MOD_PKA_2	68	74	PF00069	0.563
MOD_ProDKin_1	7	13	PF00069	0.730
MOD_ProDKin_1	71	77	PF00069	0.498
TRG_ER_diArg_1	68	70	PF00400	0.581
TRG_Pf-PMV_PEXEL_1	104	108	PF00026	0.390

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PF38	Leptomonas seymouri	56%	100%
A0A1X0NRK0	Trypanosomatidae	54%	100%
A0A3Q8IH69	Leishmania donovani	99%	100%
A0A422NHY0	Trypanosoma rangeli	53%	100%
A4HKP9	Leishmania braziliensis	83%	100%
E9B338	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q516	Leishmania major	89%	100%