LeishMANIAdb
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Ubiquitin-like domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Ubiquitin-like domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I869_LEIIN
TriTrypDb:
LINF_320031600
Length:
134

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I869
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I869

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 24 28 PF00656 0.666
CLV_C14_Caspase3-7 46 50 PF00656 0.561
CLV_PCSK_SKI1_1 107 111 PF00082 0.391
CLV_PCSK_SKI1_1 73 77 PF00082 0.509
CLV_PCSK_SKI1_1 86 90 PF00082 0.428
DOC_CYCLIN_yCln2_LP_2 109 115 PF00134 0.383
DOC_MAPK_MEF2A_6 123 132 PF00069 0.520
DOC_PP4_FxxP_1 64 67 PF00568 0.366
DOC_USP7_MATH_1 56 60 PF00917 0.526
DOC_WW_Pin1_4 4 9 PF00397 0.751
LIG_BIR_II_1 1 5 PF00653 0.690
LIG_Clathr_ClatBox_1 127 131 PF01394 0.404
LIG_CtBP_PxDLS_1 112 116 PF00389 0.527
LIG_deltaCOP1_diTrp_1 14 23 PF00928 0.578
LIG_EVH1_2 19 23 PF00568 0.583
LIG_FHA_1 99 105 PF00498 0.412
LIG_LIR_Apic_2 14 19 PF02991 0.565
LIG_LIR_Apic_2 61 67 PF02991 0.505
LIG_SH2_STAT5 103 106 PF00017 0.538
LIG_SH3_3 116 122 PF00018 0.424
LIG_SUMO_SIM_anti_2 59 64 PF11976 0.395
LIG_SUMO_SIM_par_1 111 117 PF11976 0.399
MOD_CK1_1 7 13 PF00069 0.655
MOD_CK2_1 9 15 PF00069 0.594
MOD_GlcNHglycan 2 5 PF01048 0.715
MOD_GlcNHglycan 29 32 PF01048 0.710
MOD_Plk_1 97 103 PF00069 0.421
MOD_Plk_2-3 111 117 PF00069 0.399
MOD_Plk_2-3 9 15 PF00069 0.561
MOD_Plk_4 58 64 PF00069 0.571
MOD_Plk_4 98 104 PF00069 0.414
MOD_ProDKin_1 4 10 PF00069 0.747
MOD_SUMO_for_1 122 125 PF00179 0.484
MOD_SUMO_for_1 128 131 PF00179 0.398
MOD_SUMO_rev_2 116 124 PF00179 0.480
TRG_Pf-PMV_PEXEL_1 107 111 PF00026 0.403
TRG_Pf-PMV_PEXEL_1 86 90 PF00026 0.518

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I4I3 Leptomonas seymouri 61% 98%
A0A0S4IYR4 Bodo saltans 38% 92%
A0A1X0NRU4 Trypanosomatidae 39% 100%
A0A3R7MFQ9 Trypanosoma rangeli 47% 100%
A0A3S7X5R6 Leishmania donovani 100% 100%
A4HKN8 Leishmania braziliensis 74% 100%
D0AAD8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 40% 100%
E9B327 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q4Q527 Leishmania major 93% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS