LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I842_LEIIN
TriTrypDb:
LINF_320028200
Length:
640

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I842
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I842

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 151 155 PF00656 0.757
CLV_C14_Caspase3-7 218 222 PF00656 0.633
CLV_C14_Caspase3-7 421 425 PF00656 0.627
CLV_NRD_NRD_1 11 13 PF00675 0.728
CLV_NRD_NRD_1 137 139 PF00675 0.828
CLV_NRD_NRD_1 144 146 PF00675 0.744
CLV_NRD_NRD_1 511 513 PF00675 0.760
CLV_PCSK_FUR_1 8 12 PF00082 0.604
CLV_PCSK_KEX2_1 10 12 PF00082 0.679
CLV_PCSK_KEX2_1 137 139 PF00082 0.797
CLV_PCSK_KEX2_1 144 146 PF00082 0.755
CLV_PCSK_KEX2_1 511 513 PF00082 0.760
CLV_PCSK_KEX2_1 7 9 PF00082 0.689
CLV_PCSK_PC1ET2_1 10 12 PF00082 0.679
CLV_PCSK_PC1ET2_1 7 9 PF00082 0.689
CLV_PCSK_SKI1_1 348 352 PF00082 0.673
CLV_PCSK_SKI1_1 545 549 PF00082 0.613
CLV_PCSK_SKI1_1 7 11 PF00082 0.781
DEG_SPOP_SBC_1 249 253 PF00917 0.822
DEG_SPOP_SBC_1 573 577 PF00917 0.742
DOC_CYCLIN_yCln2_LP_2 157 163 PF00134 0.672
DOC_MAPK_FxFP_2 463 466 PF00069 0.796
DOC_MAPK_gen_1 587 595 PF00069 0.750
DOC_MAPK_MEF2A_6 399 407 PF00069 0.750
DOC_PP2B_LxvP_1 157 160 PF13499 0.672
DOC_PP2B_LxvP_1 364 367 PF13499 0.719
DOC_PP4_FxxP_1 400 403 PF00568 0.820
DOC_PP4_FxxP_1 463 466 PF00568 0.796
DOC_USP7_MATH_1 118 122 PF00917 0.806
DOC_USP7_MATH_1 126 130 PF00917 0.773
DOC_USP7_MATH_1 147 151 PF00917 0.768
DOC_USP7_MATH_1 163 167 PF00917 0.569
DOC_USP7_MATH_1 189 193 PF00917 0.720
DOC_USP7_MATH_1 215 219 PF00917 0.661
DOC_USP7_MATH_1 231 235 PF00917 0.722
DOC_USP7_MATH_1 317 321 PF00917 0.764
DOC_USP7_MATH_1 328 332 PF00917 0.607
DOC_USP7_MATH_1 403 407 PF00917 0.714
DOC_USP7_MATH_1 412 416 PF00917 0.755
DOC_USP7_MATH_1 456 460 PF00917 0.750
DOC_USP7_MATH_1 49 53 PF00917 0.780
DOC_USP7_MATH_2 500 506 PF00917 0.617
DOC_WW_Pin1_4 130 135 PF00397 0.778
DOC_WW_Pin1_4 278 283 PF00397 0.725
DOC_WW_Pin1_4 365 370 PF00397 0.800
DOC_WW_Pin1_4 496 501 PF00397 0.666
DOC_WW_Pin1_4 506 511 PF00397 0.645
DOC_WW_Pin1_4 528 533 PF00397 0.770
DOC_WW_Pin1_4 66 71 PF00397 0.689
DOC_WW_Pin1_4 81 86 PF00397 0.541
LIG_14-3-3_CanoR_1 119 127 PF00244 0.640
LIG_14-3-3_CanoR_1 511 515 PF00244 0.616
LIG_APCC_ABBA_1 339 344 PF00400 0.803
LIG_BIR_III_2 60 64 PF00653 0.671
LIG_BRCT_BRCA1_1 608 612 PF00533 0.690
LIG_CtBP_PxDLS_1 375 379 PF00389 0.797
LIG_CtBP_PxDLS_1 515 519 PF00389 0.734
LIG_deltaCOP1_diTrp_1 617 623 PF00928 0.519
LIG_eIF4E_1 542 548 PF01652 0.713
LIG_FHA_1 112 118 PF00498 0.672
LIG_FHA_1 122 128 PF00498 0.601
LIG_FHA_1 234 240 PF00498 0.800
LIG_FHA_1 349 355 PF00498 0.712
LIG_FHA_1 361 367 PF00498 0.567
LIG_FHA_2 15 21 PF00498 0.699
LIG_FHA_2 24 30 PF00498 0.558
LIG_FHA_2 304 310 PF00498 0.770
LIG_FHA_2 317 323 PF00498 0.607
LIG_FHA_2 54 60 PF00498 0.754
LIG_LIR_Apic_2 351 356 PF02991 0.793
LIG_LIR_Apic_2 397 403 PF02991 0.818
LIG_LIR_Gen_1 340 350 PF02991 0.800
LIG_LIR_Gen_1 42 50 PF02991 0.561
LIG_LIR_Gen_1 485 490 PF02991 0.695
LIG_LIR_Nem_3 340 345 PF02991 0.788
LIG_LIR_Nem_3 385 391 PF02991 0.728
LIG_LIR_Nem_3 42 47 PF02991 0.558
LIG_LIR_Nem_3 434 439 PF02991 0.724
LIG_LIR_Nem_3 464 468 PF02991 0.716
LIG_LIR_Nem_3 485 489 PF02991 0.616
LIG_LIR_Nem_3 537 542 PF02991 0.623
LIG_LYPXL_S_1 435 439 PF13949 0.791
LIG_LYPXL_yS_3 436 439 PF13949 0.787
LIG_LYPXL_yS_3 465 468 PF13949 0.793
LIG_MYND_1 437 441 PF01753 0.785
LIG_PTAP_UEV_1 64 69 PF05743 0.628
LIG_Rb_pABgroove_1 606 614 PF01858 0.764
LIG_SH2_CRK 44 48 PF00017 0.700
LIG_SH2_CRK 486 490 PF00017 0.618
LIG_SH2_CRK 529 533 PF00017 0.794
LIG_SH2_NCK_1 498 502 PF00017 0.818
LIG_SH2_NCK_1 529 533 PF00017 0.716
LIG_SH2_NCK_1 567 571 PF00017 0.604
LIG_SH2_SRC 353 356 PF00017 0.798
LIG_SH2_SRC 582 585 PF00017 0.660
LIG_SH2_STAP1 633 637 PF00017 0.556
LIG_SH2_STAT5 353 356 PF00017 0.705
LIG_SH2_STAT5 44 47 PF00017 0.735
LIG_SH2_STAT5 610 613 PF00017 0.730
LIG_SH3_3 236 242 PF00018 0.626
LIG_SH3_3 335 341 PF00018 0.727
LIG_SH3_3 363 369 PF00018 0.799
LIG_SH3_3 434 440 PF00018 0.789
LIG_SH3_3 463 469 PF00018 0.716
LIG_SH3_3 601 607 PF00018 0.707
LIG_SH3_3 62 68 PF00018 0.727
LIG_SUMO_SIM_par_1 402 408 PF11976 0.617
LIG_SUMO_SIM_par_1 427 434 PF11976 0.593
LIG_WRC_WIRS_1 432 437 PF05994 0.796
MOD_CDC14_SPxK_1 368 371 PF00782 0.806
MOD_CDK_SPK_2 130 135 PF00069 0.778
MOD_CDK_SPK_2 506 511 PF00069 0.757
MOD_CDK_SPxK_1 365 371 PF00069 0.802
MOD_CDK_SPxK_1 506 512 PF00069 0.757
MOD_CDK_SPxxK_3 130 137 PF00069 0.739
MOD_CK1_1 102 108 PF00069 0.742
MOD_CK1_1 121 127 PF00069 0.649
MOD_CK1_1 130 136 PF00069 0.757
MOD_CK1_1 150 156 PF00069 0.686
MOD_CK1_1 166 172 PF00069 0.604
MOD_CK1_1 173 179 PF00069 0.673
MOD_CK1_1 180 186 PF00069 0.700
MOD_CK1_1 204 210 PF00069 0.756
MOD_CK1_1 219 225 PF00069 0.602
MOD_CK1_1 254 260 PF00069 0.705
MOD_CK1_1 270 276 PF00069 0.726
MOD_CK1_1 278 284 PF00069 0.706
MOD_CK1_1 320 326 PF00069 0.762
MOD_CK1_1 331 337 PF00069 0.670
MOD_CK1_1 431 437 PF00069 0.683
MOD_CK1_1 446 452 PF00069 0.667
MOD_CK2_1 126 132 PF00069 0.800
MOD_CK2_1 14 20 PF00069 0.700
MOD_CK2_1 206 212 PF00069 0.772
MOD_CK2_1 23 29 PF00069 0.558
MOD_CK2_1 316 322 PF00069 0.773
MOD_CK2_1 340 346 PF00069 0.642
MOD_CK2_1 444 450 PF00069 0.730
MOD_CK2_1 496 502 PF00069 0.715
MOD_CK2_1 53 59 PF00069 0.750
MOD_CK2_1 66 72 PF00069 0.599
MOD_CK2_1 81 87 PF00069 0.587
MOD_Cter_Amidation 135 138 PF01082 0.737
MOD_GlcNHglycan 165 168 PF01048 0.806
MOD_GlcNHglycan 185 188 PF01048 0.785
MOD_GlcNHglycan 204 207 PF01048 0.517
MOD_GlcNHglycan 208 211 PF01048 0.642
MOD_GlcNHglycan 217 221 PF01048 0.611
MOD_GlcNHglycan 229 232 PF01048 0.678
MOD_GlcNHglycan 291 294 PF01048 0.791
MOD_GlcNHglycan 322 325 PF01048 0.765
MOD_GlcNHglycan 416 419 PF01048 0.693
MOD_GlcNHglycan 457 461 PF01048 0.716
MOD_GlcNHglycan 576 579 PF01048 0.659
MOD_GlcNHglycan 589 592 PF01048 0.661
MOD_GlcNHglycan 77 80 PF01048 0.823
MOD_GSK3_1 126 133 PF00069 0.834
MOD_GSK3_1 166 173 PF00069 0.717
MOD_GSK3_1 174 181 PF00069 0.705
MOD_GSK3_1 202 209 PF00069 0.747
MOD_GSK3_1 215 222 PF00069 0.634
MOD_GSK3_1 227 234 PF00069 0.734
MOD_GSK3_1 244 251 PF00069 0.594
MOD_GSK3_1 266 273 PF00069 0.854
MOD_GSK3_1 298 305 PF00069 0.768
MOD_GSK3_1 316 323 PF00069 0.569
MOD_GSK3_1 424 431 PF00069 0.671
MOD_GSK3_1 49 56 PF00069 0.723
MOD_GSK3_1 492 499 PF00069 0.760
MOD_GSK3_1 502 509 PF00069 0.705
MOD_GSK3_1 510 517 PF00069 0.563
MOD_GSK3_1 537 544 PF00069 0.611
MOD_GSK3_1 587 594 PF00069 0.815
MOD_N-GLC_1 111 116 PF02516 0.755
MOD_N-GLC_1 270 275 PF02516 0.813
MOD_N-GLC_1 278 283 PF02516 0.686
MOD_N-GLC_1 317 322 PF02516 0.765
MOD_N-GLC_1 585 590 PF02516 0.737
MOD_N-GLC_1 591 596 PF02516 0.686
MOD_NEK2_1 43 48 PF00069 0.611
MOD_NEK2_1 565 570 PF00069 0.674
MOD_NEK2_1 611 616 PF00069 0.664
MOD_NEK2_1 88 93 PF00069 0.659
MOD_NEK2_2 492 497 PF00069 0.714
MOD_NMyristoyl 1 7 PF02799 0.772
MOD_PIKK_1 231 237 PF00454 0.807
MOD_PIKK_1 383 389 PF00454 0.583
MOD_PIKK_1 99 105 PF00454 0.658
MOD_PKA_2 118 124 PF00069 0.776
MOD_PKA_2 14 20 PF00069 0.656
MOD_PKA_2 169 175 PF00069 0.755
MOD_PKA_2 177 183 PF00069 0.663
MOD_PKA_2 23 29 PF00069 0.602
MOD_PKA_2 267 273 PF00069 0.690
MOD_PKA_2 412 418 PF00069 0.635
MOD_PKA_2 510 516 PF00069 0.616
MOD_Plk_1 317 323 PF00069 0.799
MOD_Plk_1 328 334 PF00069 0.679
MOD_Plk_1 492 498 PF00069 0.717
MOD_Plk_1 591 597 PF00069 0.750
MOD_Plk_1 612 618 PF00069 0.732
MOD_Plk_1 88 94 PF00069 0.629
MOD_Plk_2-3 14 20 PF00069 0.661
MOD_Plk_2-3 340 346 PF00069 0.583
MOD_Plk_4 14 20 PF00069 0.603
MOD_Plk_4 328 334 PF00069 0.784
MOD_Plk_4 431 437 PF00069 0.769
MOD_Plk_4 514 520 PF00069 0.732
MOD_Plk_4 537 543 PF00069 0.692
MOD_Plk_4 606 612 PF00069 0.745
MOD_ProDKin_1 130 136 PF00069 0.779
MOD_ProDKin_1 278 284 PF00069 0.726
MOD_ProDKin_1 365 371 PF00069 0.802
MOD_ProDKin_1 496 502 PF00069 0.671
MOD_ProDKin_1 506 512 PF00069 0.645
MOD_ProDKin_1 528 534 PF00069 0.770
MOD_ProDKin_1 66 72 PF00069 0.691
MOD_ProDKin_1 81 87 PF00069 0.540
TRG_ENDOCYTIC_2 342 345 PF00928 0.801
TRG_ENDOCYTIC_2 436 439 PF00928 0.760
TRG_ENDOCYTIC_2 44 47 PF00928 0.696
TRG_ENDOCYTIC_2 465 468 PF00928 0.793
TRG_ENDOCYTIC_2 486 489 PF00928 0.831
TRG_ER_diArg_1 143 145 PF00400 0.734
TRG_ER_diArg_1 510 512 PF00400 0.761
TRG_NLS_MonoExtC_3 6 11 PF00514 0.701

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S5H7S3 Leishmania donovani 99% 100%
A4HKK9 Leishmania braziliensis 46% 95%
E9B300 Leishmania mexicana (strain MHOM/GT/2001/U1103) 79% 100%
Q4Q556 Leishmania major 82% 99%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS