Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Cytidine and deoxycytidylate deaminase zinc-binding region containing protein - putative

Species:

Leishmania infantum

UniProt:

A4I830_LEIIN

TriTrypDb:

LINF_320026900

Length:

542

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I830

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I830

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	54	56	PF00675	0.542
CLV_PCSK_FUR_1	52	56	PF00082	0.525
CLV_PCSK_KEX2_1	393	395	PF00082	0.636
CLV_PCSK_KEX2_1	49	51	PF00082	0.474
CLV_PCSK_KEX2_1	54	56	PF00082	0.538
CLV_PCSK_PC1ET2_1	393	395	PF00082	0.605
CLV_PCSK_PC1ET2_1	49	51	PF00082	0.474
CLV_PCSK_PC7_1	50	56	PF00082	0.509
CLV_PCSK_SKI1_1	280	284	PF00082	0.393
CLV_PCSK_SKI1_1	404	408	PF00082	0.496
CLV_PCSK_SKI1_1	498	502	PF00082	0.275
CLV_PCSK_SKI1_1	55	59	PF00082	0.573
DEG_APCC_DBOX_1	513	521	PF00400	0.378
DEG_Nend_UBRbox_1	1	4	PF02207	0.417
DEG_SCF_FBW7_1	69	76	PF00400	0.656
DEG_SPOP_SBC_1	356	360	PF00917	0.438
DOC_ANK_TNKS_1	183	190	PF00023	0.555
DOC_CKS1_1	70	75	PF01111	0.666
DOC_CYCLIN_yClb5_NLxxxL_5	31	40	PF00134	0.514
DOC_CYCLIN_yCln2_LP_2	407	413	PF00134	0.394
DOC_MAPK_gen_1	49	59	PF00069	0.544
DOC_MAPK_MEF2A_6	316	325	PF00069	0.669
DOC_MAPK_MEF2A_6	32	40	PF00069	0.468
DOC_PP1_RVXF_1	127	133	PF00149	0.534
DOC_PP1_RVXF_1	496	502	PF00149	0.475
DOC_PP2B_LxvP_1	255	258	PF13499	0.483
DOC_PP2B_LxvP_1	36	39	PF13499	0.476
DOC_PP2B_PxIxI_1	320	326	PF00149	0.557
DOC_PP4_FxxP_1	442	445	PF00568	0.588
DOC_USP7_MATH_1	102	106	PF00917	0.612
DOC_USP7_MATH_1	118	122	PF00917	0.506
DOC_USP7_MATH_1	137	141	PF00917	0.637
DOC_USP7_MATH_1	155	159	PF00917	0.354
DOC_USP7_MATH_1	175	179	PF00917	0.517
DOC_USP7_MATH_1	223	227	PF00917	0.499
DOC_USP7_MATH_1	357	361	PF00917	0.432
DOC_USP7_MATH_1	455	459	PF00917	0.727
DOC_USP7_MATH_1	464	468	PF00917	0.510
DOC_USP7_MATH_2	243	249	PF00917	0.514
DOC_WW_Pin1_4	11	16	PF00397	0.495
DOC_WW_Pin1_4	317	322	PF00397	0.683
DOC_WW_Pin1_4	380	385	PF00397	0.680
DOC_WW_Pin1_4	64	69	PF00397	0.577
LIG_14-3-3_CanoR_1	304	311	PF00244	0.614
LIG_14-3-3_CanoR_1	429	433	PF00244	0.544
LIG_14-3-3_CanoR_1	462	471	PF00244	0.553
LIG_14-3-3_CanoR_1	54	60	PF00244	0.622
LIG_BIR_III_4	107	111	PF00653	0.633
LIG_BRCT_BRCA1_1	150	154	PF00533	0.424
LIG_BRCT_BRCA1_1	225	229	PF00533	0.457
LIG_deltaCOP1_diTrp_1	245	253	PF00928	0.479
LIG_FHA_1	12	18	PF00498	0.496
LIG_FHA_1	155	161	PF00498	0.465
LIG_FHA_1	269	275	PF00498	0.382
LIG_FHA_1	350	356	PF00498	0.534
LIG_FHA_1	92	98	PF00498	0.609
LIG_FHA_2	133	139	PF00498	0.502
LIG_FHA_2	381	387	PF00498	0.508
LIG_IRF3_LxIS_1	15	22	PF10401	0.447
LIG_LIR_Gen_1	226	236	PF02991	0.448
LIG_LIR_Gen_1	537	542	PF02991	0.447
LIG_LIR_Nem_3	537	542	PF02991	0.447
LIG_NRBOX	76	82	PF00104	0.585
LIG_PCNA_PIPBox_1	520	529	PF02747	0.422
LIG_PDZ_Class_1	537	542	PF00595	0.472
LIG_REV1ctd_RIR_1	498	508	PF16727	0.563
LIG_SH2_CRK	376	380	PF00017	0.533
LIG_SH2_STAT5	200	203	PF00017	0.778
LIG_SH2_STAT5	376	379	PF00017	0.444
LIG_SH2_STAT5	470	473	PF00017	0.398
LIG_SH2_STAT5	478	481	PF00017	0.467
LIG_SH2_STAT5	539	542	PF00017	0.500
LIG_SH3_3	254	260	PF00018	0.476
LIG_SH3_3	344	350	PF00018	0.409
LIG_SH3_3	364	370	PF00018	0.311
LIG_SH3_3	397	403	PF00018	0.564
LIG_SH3_3	62	68	PF00018	0.614
LIG_SH3_CIN85_PxpxPR_1	254	259	PF14604	0.559
LIG_SUMO_SIM_anti_2	342	349	PF11976	0.398
LIG_SUMO_SIM_anti_2	75	81	PF11976	0.656
LIG_SUMO_SIM_par_1	16	23	PF11976	0.422
LIG_TRAF2_1	326	329	PF00917	0.645
MOD_CK1_1	171	177	PF00069	0.591
MOD_CK1_1	202	208	PF00069	0.623
MOD_CK1_1	303	309	PF00069	0.656
MOD_CK1_1	360	366	PF00069	0.518
MOD_CK1_1	454	460	PF00069	0.586
MOD_CK1_1	96	102	PF00069	0.629
MOD_CK2_1	132	138	PF00069	0.497
MOD_CK2_1	321	327	PF00069	0.664
MOD_CK2_1	525	531	PF00069	0.388
MOD_CK2_1	72	78	PF00069	0.622
MOD_GlcNHglycan	115	118	PF01048	0.585
MOD_GlcNHglycan	170	173	PF01048	0.529
MOD_GlcNHglycan	177	180	PF01048	0.611
MOD_GlcNHglycan	247	250	PF01048	0.507
MOD_GlcNHglycan	266	269	PF01048	0.328
MOD_GlcNHglycan	359	362	PF01048	0.446
MOD_GlcNHglycan	453	456	PF01048	0.570
MOD_GlcNHglycan	527	530	PF01048	0.379
MOD_GSK3_1	149	156	PF00069	0.500
MOD_GSK3_1	171	178	PF00069	0.476
MOD_GSK3_1	194	201	PF00069	0.741
MOD_GSK3_1	210	217	PF00069	0.525
MOD_GSK3_1	230	237	PF00069	0.472
MOD_GSK3_1	264	271	PF00069	0.439
MOD_GSK3_1	300	307	PF00069	0.431
MOD_GSK3_1	312	319	PF00069	0.651
MOD_GSK3_1	356	363	PF00069	0.420
MOD_GSK3_1	428	435	PF00069	0.586
MOD_GSK3_1	440	447	PF00069	0.526
MOD_GSK3_1	450	457	PF00069	0.609
MOD_GSK3_1	60	67	PF00069	0.623
MOD_GSK3_1	69	76	PF00069	0.639
MOD_GSK3_1	93	100	PF00069	0.612
MOD_N-GLC_1	100	105	PF02516	0.544
MOD_N-GLC_1	464	469	PF02516	0.564
MOD_NEK2_1	154	159	PF00069	0.502
MOD_NEK2_1	166	171	PF00069	0.320
MOD_NEK2_1	491	496	PF00069	0.312
MOD_NEK2_1	519	524	PF00069	0.363
MOD_NEK2_2	361	366	PF00069	0.432
MOD_PKA_2	300	306	PF00069	0.512
MOD_PKA_2	428	434	PF00069	0.597
MOD_Plk_1	137	143	PF00069	0.513
MOD_Plk_1	386	392	PF00069	0.595
MOD_Plk_4	26	32	PF00069	0.407
MOD_Plk_4	55	61	PF00069	0.544
MOD_Plk_4	93	99	PF00069	0.621
MOD_ProDKin_1	11	17	PF00069	0.494
MOD_ProDKin_1	317	323	PF00069	0.685
MOD_ProDKin_1	380	386	PF00069	0.682
MOD_ProDKin_1	64	70	PF00069	0.577
MOD_SUMO_rev_2	22	27	PF00179	0.451
TRG_DiLeu_BaEn_1	336	341	PF01217	0.578
TRG_DiLeu_BaLyEn_6	126	131	PF01217	0.569
TRG_DiLeu_BaLyEn_6	145	150	PF01217	0.304
TRG_DiLeu_BaLyEn_6	401	406	PF01217	0.546
TRG_ENDOCYTIC_2	376	379	PF00928	0.520
TRG_ENDOCYTIC_2	539	542	PF00928	0.500
TRG_ER_diArg_1	50	53	PF00400	0.481
TRG_NLS_MonoExtC_3	48	53	PF00514	0.479
TRG_Pf-PMV_PEXEL_1	148	153	PF00026	0.388
TRG_Pf-PMV_PEXEL_1	404	408	PF00026	0.496

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HXU5	Leptomonas seymouri	43%	100%
A0A3Q8IL67	Leishmania donovani	100%	100%
A4HKJ8	Leishmania braziliensis	70%	99%
E9B2Y8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4Q568	Leishmania major	90%	100%