G-patch domain-containing protein

Quick info Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I821_LEIIN

TriTrypDb:

LINF_320026000

Length:

120

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Phosphorylation

Promastigote/Amastigote: 33

Expansion

Sequence features

A4I821

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I821

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	116	118	PF00675	0.774
CLV_NRD_NRD_1	38	40	PF00675	0.608
CLV_NRD_NRD_1	79	81	PF00675	0.757
CLV_PCSK_KEX2_1	116	118	PF00082	0.774
CLV_PCSK_KEX2_1	14	16	PF00082	0.592
CLV_PCSK_KEX2_1	79	81	PF00082	0.757
CLV_PCSK_PC1ET2_1	14	16	PF00082	0.643
DOC_ANK_TNKS_1	79	86	PF00023	0.746
DOC_WW_Pin1_4	115	120	PF00397	0.578
LIG_BIR_II_1	1	5	PF00653	0.693
LIG_LIR_Apic_2	108	113	PF02991	0.715
LIG_PDZ_Class_1	115	120	PF00595	0.578
LIG_PROFILIN_1	101	107	PF00235	0.680
LIG_SH2_CRK	110	114	PF00017	0.717
LIG_SH2_NCK_1	110	114	PF00017	0.717
LIG_SH3_1	99	105	PF00018	0.670
LIG_SH3_3	6	12	PF00018	0.677
LIG_SH3_3	98	104	PF00018	0.681
LIG_WW_2	104	107	PF00397	0.677
MOD_GlcNHglycan	32	35	PF01048	0.637
MOD_PIKK_1	44	50	PF00454	0.719
MOD_PIKK_1	51	57	PF00454	0.581
MOD_PIKK_1	58	64	PF00454	0.615
TRG_ER_diArg_1	17	20	PF00400	0.636
TRG_ER_diArg_1	78	80	PF00400	0.753

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I4P7	Leptomonas seymouri	59%	100%
A0A3S7X5P3	Leishmania donovani	86%	95%
A4HKI9	Leishmania braziliensis	66%	93%
E9B2X9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	73%	90%
Q4Q577	Leishmania major	78%	92%