rRNA-processing protein FYV7

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Protein of unknown function (DUF2946), putative

Species:

Leishmania infantum

UniProt:

A4I807_LEIIN

TriTrypDb:

Length:

190

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I807

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I807

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	101	103	PF00675	0.279
CLV_NRD_NRD_1	132	134	PF00675	0.349
CLV_NRD_NRD_1	157	159	PF00675	0.296
CLV_NRD_NRD_1	26	28	PF00675	0.420
CLV_NRD_NRD_1	47	49	PF00675	0.293
CLV_NRD_NRD_1	67	69	PF00675	0.347
CLV_NRD_NRD_1	7	9	PF00675	0.508
CLV_NRD_NRD_1	95	97	PF00675	0.278
CLV_PCSK_KEX2_1	101	103	PF00082	0.282
CLV_PCSK_KEX2_1	118	120	PF00082	0.301
CLV_PCSK_KEX2_1	131	133	PF00082	0.330
CLV_PCSK_KEX2_1	167	169	PF00082	0.340
CLV_PCSK_KEX2_1	26	28	PF00082	0.434
CLV_PCSK_KEX2_1	59	61	PF00082	0.382
CLV_PCSK_KEX2_1	6	8	PF00082	0.516
CLV_PCSK_KEX2_1	95	97	PF00082	0.280
CLV_PCSK_PC1ET2_1	101	103	PF00082	0.282
CLV_PCSK_PC1ET2_1	118	120	PF00082	0.284
CLV_PCSK_PC1ET2_1	167	169	PF00082	0.381
CLV_PCSK_PC1ET2_1	59	61	PF00082	0.295
CLV_PCSK_PC1ET2_1	6	8	PF00082	0.470
CLV_PCSK_PC1ET2_1	95	97	PF00082	0.280
CLV_PCSK_SKI1_1	161	165	PF00082	0.399
CLV_PCSK_SKI1_1	17	21	PF00082	0.528
CLV_PCSK_SKI1_1	26	30	PF00082	0.498
CLV_PCSK_SKI1_1	69	73	PF00082	0.330
DEG_APCC_KENBOX_2	71	75	PF00400	0.237
DOC_CYCLIN_yClb5_NLxxxL_5	72	79	PF00134	0.237
DOC_USP7_MATH_1	157	161	PF00917	0.409
DOC_USP7_MATH_1	174	178	PF00917	0.320
DOC_USP7_UBL2_3	167	171	PF12436	0.409
DOC_USP7_UBL2_3	93	97	PF12436	0.294
LIG_14-3-3_CanoR_1	119	126	PF00244	0.454
LIG_BIR_II_1	1	5	PF00653	0.671
LIG_FHA_2	106	112	PF00498	0.266
LIG_FHA_2	87	93	PF00498	0.290
LIG_LIR_Nem_3	45	50	PF02991	0.277
LIG_REV1ctd_RIR_1	18	27	PF16727	0.534
LIG_SH2_CRK	120	124	PF00017	0.365
LIG_SH2_CRK	47	51	PF00017	0.295
LIG_SH2_NCK_1	120	124	PF00017	0.374
LIG_SH2_STAP1	84	88	PF00017	0.334
LIG_TRAF2_1	143	146	PF00917	0.274
MOD_CK1_1	121	127	PF00069	0.471
MOD_CK2_1	121	127	PF00069	0.333
MOD_CK2_1	175	181	PF00069	0.409
MOD_CK2_1	74	80	PF00069	0.311
MOD_CK2_1	86	92	PF00069	0.214
MOD_Cter_Amidation	4	7	PF01082	0.620
MOD_GlcNHglycan	120	123	PF01048	0.390
MOD_GSK3_1	175	182	PF00069	0.403
MOD_N-GLC_1	73	78	PF02516	0.237
MOD_NEK2_1	104	109	PF00069	0.355
MOD_PKA_1	118	124	PF00069	0.312
MOD_PKA_2	118	124	PF00069	0.212
MOD_PKA_2	157	163	PF00069	0.466
MOD_Plk_1	84	90	PF00069	0.270
MOD_Plk_4	179	185	PF00069	0.372
MOD_SUMO_for_1	13	16	PF00179	0.472
TRG_ENDOCYTIC_2	120	123	PF00928	0.365
TRG_ENDOCYTIC_2	47	50	PF00928	0.294
TRG_ER_diArg_1	131	133	PF00400	0.212
TRG_ER_diArg_1	25	27	PF00400	0.417
TRG_ER_diArg_1	41	44	PF00400	0.297
TRG_NLS_MonoCore_2	5	10	PF00514	0.465
TRG_NLS_MonoCore_2	93	98	PF00514	0.295
TRG_NLS_MonoExtC_3	166	171	PF00514	0.409
TRG_NLS_MonoExtN_4	93	99	PF00514	0.295
TRG_Pf-PMV_PEXEL_1	48	53	PF00026	0.308

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMW6	Leptomonas seymouri	76%	100%
A0A0S4J953	Bodo saltans	46%	84%
A0A1X0NUH7	Trypanosomatidae	51%	96%
A0A3R7KF30	Trypanosoma rangeli	49%	96%
A0A3S7X5G7	Leishmania donovani	98%	100%
A4HKD6	Leishmania braziliensis	85%	100%
D0AA30	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	94%
E9B2S4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4Q5D3	Leishmania major	92%	100%