SDA1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I7Z4_LEIIN

TriTrypDb:

LINF_320023700

Length:

244

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I7Z4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I7Z4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	108	112	PF00656	0.598
CLV_NRD_NRD_1	143	145	PF00675	0.506
CLV_NRD_NRD_1	167	169	PF00675	0.636
CLV_NRD_NRD_1	19	21	PF00675	0.515
CLV_NRD_NRD_1	194	196	PF00675	0.563
CLV_NRD_NRD_1	235	237	PF00675	0.551
CLV_NRD_NRD_1	45	47	PF00675	0.516
CLV_NRD_NRD_1	66	68	PF00675	0.440
CLV_PCSK_KEX2_1	142	144	PF00082	0.520
CLV_PCSK_KEX2_1	167	169	PF00082	0.633
CLV_PCSK_KEX2_1	19	21	PF00082	0.516
CLV_PCSK_KEX2_1	194	196	PF00082	0.774
CLV_PCSK_KEX2_1	31	33	PF00082	0.496
CLV_PCSK_KEX2_1	38	40	PF00082	0.545
CLV_PCSK_KEX2_1	66	68	PF00082	0.440
CLV_PCSK_PC1ET2_1	31	33	PF00082	0.517
CLV_PCSK_PC1ET2_1	38	40	PF00082	0.611
CLV_PCSK_SKI1_1	23	27	PF00082	0.462
DEG_Nend_UBRbox_1	1	4	PF02207	0.645
DOC_MAPK_gen_1	26	36	PF00069	0.434
DOC_USP7_MATH_1	239	243	PF00917	0.530
DOC_USP7_MATH_1	84	88	PF00917	0.598
DOC_USP7_MATH_1	99	103	PF00917	0.615
DOC_USP7_UBL2_3	77	81	PF12436	0.579
DOC_WW_Pin1_4	162	167	PF00397	0.522
LIG_14-3-3_CanoR_1	118	125	PF00244	0.524
LIG_14-3-3_CanoR_1	222	231	PF00244	0.618
LIG_BRCT_BRCA1_1	6	10	PF00533	0.584
LIG_FHA_1	238	244	PF00498	0.536
LIG_FHA_1	28	34	PF00498	0.436
LIG_RPA_C_Fungi	138	150	PF08784	0.509
LIG_SH2_STAT5	63	66	PF00017	0.452
LIG_TRAF2_1	49	52	PF00917	0.446
MOD_CDK_SPK_2	162	167	PF00069	0.516
MOD_CDK_SPxK_1	162	168	PF00069	0.517
MOD_CK1_1	110	116	PF00069	0.615
MOD_CK1_1	12	18	PF00069	0.392
MOD_CK1_1	54	60	PF00069	0.435
MOD_CK2_1	118	124	PF00069	0.616
MOD_CK2_1	12	18	PF00069	0.519
MOD_CK2_1	227	233	PF00069	0.539
MOD_CK2_1	94	100	PF00069	0.621
MOD_Cter_Amidation	192	195	PF01082	0.563
MOD_GlcNHglycan	120	123	PF01048	0.625
MOD_GlcNHglycan	203	206	PF01048	0.671
MOD_GlcNHglycan	211	214	PF01048	0.623
MOD_GlcNHglycan	85	89	PF01048	0.616
MOD_GlcNHglycan	96	99	PF01048	0.643
MOD_GSK3_1	107	114	PF00069	0.570
MOD_GSK3_1	223	230	PF00069	0.592
MOD_LATS_1	220	226	PF00433	0.622
MOD_N-GLC_1	223	228	PF02516	0.661
MOD_NEK2_1	27	32	PF00069	0.458
MOD_NEK2_1	59	64	PF00069	0.439
MOD_NEK2_2	239	244	PF00069	0.538
MOD_NEK2_2	9	14	PF00069	0.409
MOD_PKA_2	161	167	PF00069	0.753
MOD_PKA_2	209	215	PF00069	0.701
MOD_PKA_2	216	222	PF00069	0.583
MOD_Plk_1	110	116	PF00069	0.599
MOD_Plk_1	51	57	PF00069	0.441
MOD_Plk_4	59	65	PF00069	0.446
MOD_ProDKin_1	162	168	PF00069	0.523
TRG_ER_diArg_1	142	144	PF00400	0.644
TRG_ER_diArg_1	166	168	PF00400	0.637
TRG_ER_diArg_1	65	67	PF00400	0.444
TRG_NLS_Bipartite_1	19	41	PF00514	0.447
TRG_NLS_MonoExtN_4	35	41	PF00514	0.429

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFN4	Leptomonas seymouri	52%	100%
A0A3Q8IH03	Leishmania donovani	94%	100%
A4HKG7	Leishmania braziliensis	61%	99%
E9B2V6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	97%
Q4Q5A0	Leishmania major	86%	100%