Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I7Y5_LEIIN

TriTrypDb:

LINF_320022700

Length:

840

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I7Y5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I7Y5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	127	131	PF00656	0.557
CLV_C14_Caspase3-7	734	738	PF00656	0.567
CLV_NRD_NRD_1	170	172	PF00675	0.610
CLV_NRD_NRD_1	256	258	PF00675	0.621
CLV_NRD_NRD_1	38	40	PF00675	0.589
CLV_NRD_NRD_1	538	540	PF00675	0.578
CLV_NRD_NRD_1	647	649	PF00675	0.559
CLV_NRD_NRD_1	729	731	PF00675	0.508
CLV_NRD_NRD_1	795	797	PF00675	0.560
CLV_PCSK_FUR_1	35	39	PF00082	0.612
CLV_PCSK_KEX2_1	170	172	PF00082	0.610
CLV_PCSK_KEX2_1	37	39	PF00082	0.582
CLV_PCSK_KEX2_1	385	387	PF00082	0.610
CLV_PCSK_KEX2_1	538	540	PF00082	0.546
CLV_PCSK_KEX2_1	647	649	PF00082	0.580
CLV_PCSK_KEX2_1	729	731	PF00082	0.587
CLV_PCSK_KEX2_1	795	797	PF00082	0.560
CLV_PCSK_PC1ET2_1	385	387	PF00082	0.610
CLV_PCSK_SKI1_1	146	150	PF00082	0.558
CLV_PCSK_SKI1_1	39	43	PF00082	0.539
CLV_PCSK_SKI1_1	406	410	PF00082	0.421
CLV_PCSK_SKI1_1	501	505	PF00082	0.479
CLV_PCSK_SKI1_1	730	734	PF00082	0.596
DEG_APCC_DBOX_1	405	413	PF00400	0.436
DEG_APCC_DBOX_1	500	508	PF00400	0.450
DEG_Nend_UBRbox_3	1	3	PF02207	0.543
DEG_SPOP_SBC_1	559	563	PF00917	0.566
DEG_SPOP_SBC_1	743	747	PF00917	0.529
DOC_CKS1_1	623	628	PF01111	0.695
DOC_CKS1_1	640	645	PF01111	0.491
DOC_CKS1_1	767	772	PF01111	0.571
DOC_CYCLIN_RxL_1	410	422	PF00134	0.421
DOC_CYCLIN_yCln2_LP_2	237	243	PF00134	0.529
DOC_MAPK_gen_1	35	44	PF00069	0.519
DOC_MAPK_gen_1	6	14	PF00069	0.483
DOC_MAPK_gen_1	601	608	PF00069	0.401
DOC_PP1_RVXF_1	245	251	PF00149	0.598
DOC_PP1_RVXF_1	589	596	PF00149	0.428
DOC_PP2B_LxvP_1	722	725	PF13499	0.471
DOC_PP4_FxxP_1	615	618	PF00568	0.728
DOC_USP7_MATH_1	121	125	PF00917	0.607
DOC_USP7_MATH_1	158	162	PF00917	0.528
DOC_USP7_MATH_1	291	295	PF00917	0.609
DOC_USP7_MATH_1	326	330	PF00917	0.587
DOC_USP7_MATH_1	487	491	PF00917	0.575
DOC_USP7_MATH_1	495	499	PF00917	0.508
DOC_USP7_MATH_1	532	536	PF00917	0.545
DOC_USP7_MATH_1	540	544	PF00917	0.549
DOC_USP7_MATH_1	560	564	PF00917	0.600
DOC_USP7_MATH_1	72	76	PF00917	0.609
DOC_USP7_MATH_1	761	765	PF00917	0.537
DOC_USP7_MATH_1	77	81	PF00917	0.596
DOC_USP7_MATH_1	787	791	PF00917	0.573
DOC_USP7_MATH_1	94	98	PF00917	0.539
DOC_WW_Pin1_4	129	134	PF00397	0.605
DOC_WW_Pin1_4	205	210	PF00397	0.587
DOC_WW_Pin1_4	231	236	PF00397	0.587
DOC_WW_Pin1_4	263	268	PF00397	0.612
DOC_WW_Pin1_4	29	34	PF00397	0.542
DOC_WW_Pin1_4	292	297	PF00397	0.569
DOC_WW_Pin1_4	331	336	PF00397	0.538
DOC_WW_Pin1_4	342	347	PF00397	0.548
DOC_WW_Pin1_4	365	370	PF00397	0.521
DOC_WW_Pin1_4	622	627	PF00397	0.700
DOC_WW_Pin1_4	639	644	PF00397	0.493
DOC_WW_Pin1_4	676	681	PF00397	0.449
DOC_WW_Pin1_4	710	715	PF00397	0.449
DOC_WW_Pin1_4	751	756	PF00397	0.585
DOC_WW_Pin1_4	766	771	PF00397	0.576
DOC_WW_Pin1_4	785	790	PF00397	0.555
DOC_WW_Pin1_4	806	811	PF00397	0.597
LIG_14-3-3_CanoR_1	107	112	PF00244	0.567
LIG_14-3-3_CanoR_1	170	180	PF00244	0.607
LIG_14-3-3_CanoR_1	263	267	PF00244	0.601
LIG_14-3-3_CanoR_1	299	307	PF00244	0.605
LIG_14-3-3_CanoR_1	314	323	PF00244	0.576
LIG_14-3-3_CanoR_1	39	45	PF00244	0.605
LIG_14-3-3_CanoR_1	448	452	PF00244	0.441
LIG_14-3-3_CanoR_1	456	462	PF00244	0.445
LIG_14-3-3_CanoR_1	591	596	PF00244	0.472
LIG_14-3-3_CanoR_1	609	618	PF00244	0.464
LIG_14-3-3_CanoR_1	62	71	PF00244	0.665
LIG_14-3-3_CanoR_1	647	655	PF00244	0.505
LIG_14-3-3_CanoR_1	686	694	PF00244	0.447
LIG_14-3-3_CanoR_1	762	766	PF00244	0.591
LIG_14-3-3_CanoR_1	795	804	PF00244	0.549
LIG_14-3-3_CanoR_1	819	824	PF00244	0.620
LIG_Actin_WH2_2	593	611	PF00022	0.439
LIG_Actin_WH2_2	662	679	PF00022	0.403
LIG_BIR_III_2	130	134	PF00653	0.558
LIG_deltaCOP1_diTrp_1	426	433	PF00928	0.457
LIG_Dynein_DLC8_1	312	318	PF01221	0.611
LIG_EH1_1	776	784	PF00400	0.576
LIG_FHA_1	121	127	PF00498	0.607
LIG_FHA_1	16	22	PF00498	0.427
LIG_FHA_1	217	223	PF00498	0.618
LIG_FHA_1	232	238	PF00498	0.479
LIG_FHA_1	618	624	PF00498	0.644
LIG_FHA_1	717	723	PF00498	0.501
LIG_FHA_1	820	826	PF00498	0.539
LIG_FHA_2	314	320	PF00498	0.573
LIG_FHA_2	450	456	PF00498	0.491
LIG_FHA_2	509	515	PF00498	0.523
LIG_FHA_2	570	576	PF00498	0.608
LIG_FHA_2	85	91	PF00498	0.601
LIG_LIR_Apic_2	613	618	PF02991	0.597
LIG_LIR_Gen_1	430	440	PF02991	0.399
LIG_LIR_Gen_1	589	600	PF02991	0.408
LIG_LIR_Gen_1	672	681	PF02991	0.434
LIG_LIR_Gen_1	697	705	PF02991	0.460
LIG_LIR_Nem_3	364	370	PF02991	0.520
LIG_LIR_Nem_3	430	436	PF02991	0.408
LIG_LIR_Nem_3	589	595	PF02991	0.431
LIG_LIR_Nem_3	672	676	PF02991	0.415
LIG_LIR_Nem_3	679	685	PF02991	0.427
LIG_LIR_Nem_3	697	701	PF02991	0.605
LIG_LIR_Nem_3	802	807	PF02991	0.590
LIG_PCNA_APIM_2	404	410	PF02747	0.377
LIG_Pex14_1	433	437	PF04695	0.397
LIG_Pex14_2	517	521	PF04695	0.542
LIG_Pex14_2	694	698	PF04695	0.491
LIG_SH2_CRK	437	441	PF00017	0.422
LIG_SH2_CRK	804	808	PF00017	0.600
LIG_SH2_SRC	528	531	PF00017	0.521
LIG_SH2_STAT5	407	410	PF00017	0.406
LIG_SH2_STAT5	437	440	PF00017	0.382
LIG_SH2_STAT5	528	531	PF00017	0.521
LIG_SH3_1	290	296	PF00018	0.615
LIG_SH3_3	290	296	PF00018	0.615
LIG_SH3_3	343	349	PF00018	0.528
LIG_SH3_3	399	405	PF00018	0.480
LIG_SH3_3	494	500	PF00018	0.555
LIG_SH3_3	526	532	PF00018	0.517
LIG_SH3_3	554	560	PF00018	0.604
LIG_SH3_3	764	770	PF00018	0.578
LIG_SUMO_SIM_anti_2	23	28	PF11976	0.479
LIG_SUMO_SIM_par_1	17	23	PF11976	0.419
LIG_SUMO_SIM_par_1	441	450	PF11976	0.391
LIG_SUMO_SIM_par_1	718	723	PF11976	0.506
LIG_SUMO_SIM_par_1	821	827	PF11976	0.613
LIG_TRAF2_1	424	427	PF00917	0.468
LIG_TRAF2_1	725	728	PF00917	0.474
LIG_TRAF2_1	814	817	PF00917	0.529
LIG_Vh1_VBS_1	12	30	PF01044	0.499
LIG_WRC_WIRS_1	592	597	PF05994	0.405
LIG_WRC_WIRS_1	670	675	PF05994	0.388
MOD_CDK_SPxK_1	29	35	PF00069	0.580
MOD_CDK_SPxK_1	331	337	PF00069	0.542
MOD_CDK_SPxK_1	766	772	PF00069	0.574
MOD_CDK_SPxxK_3	129	136	PF00069	0.606
MOD_CDK_SPxxK_3	292	299	PF00069	0.620
MOD_CK1_1	129	135	PF00069	0.605
MOD_CK1_1	15	21	PF00069	0.405
MOD_CK1_1	294	300	PF00069	0.575
MOD_CK1_1	329	335	PF00069	0.523
MOD_CK1_1	446	452	PF00069	0.540
MOD_CK1_1	458	464	PF00069	0.442
MOD_CK1_1	562	568	PF00069	0.576
MOD_CK1_1	63	69	PF00069	0.588
MOD_CK1_1	713	719	PF00069	0.497
MOD_CK1_1	742	748	PF00069	0.619
MOD_CK1_1	751	757	PF00069	0.727
MOD_CK1_1	790	796	PF00069	0.583
MOD_CK1_1	824	830	PF00069	0.577
MOD_CK2_1	121	127	PF00069	0.607
MOD_CK2_1	313	319	PF00069	0.625
MOD_CK2_1	544	550	PF00069	0.600
MOD_CK2_1	569	575	PF00069	0.663
MOD_CK2_1	700	706	PF00069	0.422
MOD_Cter_Amidation	255	258	PF01082	0.539
MOD_DYRK1A_RPxSP_1	766	770	PF00069	0.610
MOD_GlcNHglycan	152	155	PF01048	0.563
MOD_GlcNHglycan	175	178	PF01048	0.609
MOD_GlcNHglycan	183	186	PF01048	0.535
MOD_GlcNHglycan	194	197	PF01048	0.485
MOD_GlcNHglycan	319	323	PF01048	0.765
MOD_GlcNHglycan	328	331	PF01048	0.603
MOD_GlcNHglycan	457	460	PF01048	0.426
MOD_GlcNHglycan	489	492	PF01048	0.604
MOD_GlcNHglycan	52	55	PF01048	0.609
MOD_GlcNHglycan	534	537	PF01048	0.535
MOD_GlcNHglycan	542	545	PF01048	0.764
MOD_GlcNHglycan	702	705	PF01048	0.376
MOD_GlcNHglycan	715	718	PF01048	0.450
MOD_GlcNHglycan	750	753	PF01048	0.613
MOD_GlcNHglycan	759	762	PF01048	0.555
MOD_GlcNHglycan	789	792	PF01048	0.603
MOD_GlcNHglycan	79	82	PF01048	0.614
MOD_GSK3_1	121	128	PF00069	0.606
MOD_GSK3_1	194	201	PF00069	0.563
MOD_GSK3_1	212	219	PF00069	0.591
MOD_GSK3_1	294	301	PF00069	0.593
MOD_GSK3_1	313	320	PF00069	0.648
MOD_GSK3_1	42	49	PF00069	0.604
MOD_GSK3_1	443	450	PF00069	0.620
MOD_GSK3_1	540	547	PF00069	0.594
MOD_GSK3_1	558	565	PF00069	0.472
MOD_GSK3_1	587	594	PF00069	0.652
MOD_GSK3_1	60	67	PF00069	0.525
MOD_GSK3_1	638	645	PF00069	0.590
MOD_GSK3_1	646	653	PF00069	0.544
MOD_GSK3_1	665	672	PF00069	0.403
MOD_GSK3_1	681	688	PF00069	0.432
MOD_GSK3_1	738	745	PF00069	0.589
MOD_GSK3_1	750	757	PF00069	0.588
MOD_GSK3_1	77	84	PF00069	0.579
MOD_GSK3_1	781	788	PF00069	0.545
MOD_GSK3_1	790	797	PF00069	0.573
MOD_GSK3_1	94	101	PF00069	0.726
MOD_LATS_1	599	605	PF00433	0.438
MOD_N-GLC_1	263	268	PF02516	0.673
MOD_N-GLC_1	352	357	PF02516	0.535
MOD_N-GLC_1	487	492	PF02516	0.524
MOD_NEK2_1	20	25	PF00069	0.448
MOD_NEK2_1	42	47	PF00069	0.536
MOD_NEK2_1	507	512	PF00069	0.515
MOD_NEK2_1	564	569	PF00069	0.602
MOD_NEK2_1	681	686	PF00069	0.465
MOD_NEK2_2	761	766	PF00069	0.539
MOD_PIKK_1	201	207	PF00454	0.577
MOD_PIKK_1	313	319	PF00454	0.653
MOD_PIKK_1	388	394	PF00454	0.586
MOD_PIKK_1	610	616	PF00454	0.578
MOD_PIKK_1	795	801	PF00454	0.567
MOD_PIKK_1	98	104	PF00454	0.617
MOD_PK_1	398	404	PF00069	0.527
MOD_PK_1	739	745	PF00069	0.546
MOD_PK_1	821	827	PF00069	0.538
MOD_PKA_1	601	607	PF00069	0.471
MOD_PKA_1	795	801	PF00069	0.521
MOD_PKA_2	262	268	PF00069	0.602
MOD_PKA_2	298	304	PF00069	0.778
MOD_PKA_2	313	319	PF00069	0.609
MOD_PKA_2	447	453	PF00069	0.460
MOD_PKA_2	455	461	PF00069	0.454
MOD_PKA_2	540	546	PF00069	0.550
MOD_PKA_2	63	69	PF00069	0.588
MOD_PKA_2	646	652	PF00069	0.515
MOD_PKA_2	685	691	PF00069	0.446
MOD_PKA_2	738	744	PF00069	0.542
MOD_PKA_2	761	767	PF00069	0.585
MOD_PKA_2	794	800	PF00069	0.599
MOD_PKB_1	62	70	PF00069	0.665
MOD_PKB_1	819	827	PF00069	0.619
MOD_Plk_1	243	249	PF00069	0.511
MOD_Plk_1	318	324	PF00069	0.578
MOD_Plk_1	480	486	PF00069	0.553
MOD_Plk_1	576	582	PF00069	0.619
MOD_Plk_1	739	745	PF00069	0.539
MOD_Plk_2-3	576	582	PF00069	0.598
MOD_Plk_4	15	21	PF00069	0.434
MOD_Plk_4	354	360	PF00069	0.480
MOD_Plk_4	398	404	PF00069	0.527
MOD_Plk_4	435	441	PF00069	0.417
MOD_Plk_4	591	597	PF00069	0.424
MOD_Plk_4	665	671	PF00069	0.396
MOD_Plk_4	7	13	PF00069	0.476
MOD_Plk_4	716	722	PF00069	0.509
MOD_ProDKin_1	129	135	PF00069	0.605
MOD_ProDKin_1	205	211	PF00069	0.585
MOD_ProDKin_1	231	237	PF00069	0.585
MOD_ProDKin_1	263	269	PF00069	0.612
MOD_ProDKin_1	29	35	PF00069	0.546
MOD_ProDKin_1	292	298	PF00069	0.571
MOD_ProDKin_1	331	337	PF00069	0.540
MOD_ProDKin_1	342	348	PF00069	0.546
MOD_ProDKin_1	365	371	PF00069	0.522
MOD_ProDKin_1	622	628	PF00069	0.697
MOD_ProDKin_1	639	645	PF00069	0.492
MOD_ProDKin_1	676	682	PF00069	0.443
MOD_ProDKin_1	710	716	PF00069	0.445
MOD_ProDKin_1	751	757	PF00069	0.587
MOD_ProDKin_1	766	772	PF00069	0.574
MOD_ProDKin_1	785	791	PF00069	0.556
MOD_ProDKin_1	806	812	PF00069	0.597
MOD_SUMO_rev_2	514	524	PF00179	0.478
TRG_DiLeu_BaEn_1	502	507	PF01217	0.476
TRG_DiLeu_BaEn_2	8	14	PF01217	0.466
TRG_DiLeu_BaLyEn_6	414	419	PF01217	0.424
TRG_DiLeu_BaLyEn_6	704	709	PF01217	0.400
TRG_ENDOCYTIC_2	437	440	PF00928	0.382
TRG_ENDOCYTIC_2	603	606	PF00928	0.373
TRG_ENDOCYTIC_2	804	807	PF00928	0.597
TRG_ER_diArg_1	169	171	PF00400	0.611
TRG_ER_diArg_1	35	38	PF00400	0.674
TRG_ER_diArg_1	538	541	PF00400	0.510
TRG_ER_diArg_1	606	609	PF00400	0.527
TRG_ER_diArg_1	674	677	PF00400	0.416
TRG_ER_diArg_1	68	71	PF00400	0.809
TRG_ER_diArg_1	729	731	PF00400	0.508
TRG_ER_diArg_1	765	768	PF00400	0.585
TRG_Pf-PMV_PEXEL_1	410	415	PF00026	0.419
TRG_Pf-PMV_PEXEL_1	417	421	PF00026	0.412
TRG_Pf-PMV_PEXEL_1	98	102	PF00026	0.535

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I482	Leptomonas seymouri	39%	100%
E9B2U6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%