Uncharacterized protein

Quick info Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I7X8_LEIIN

TriTrypDb:

LINF_320022000

Length:

250

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Phosphorylation

Promastigote: 68

Expansion

Sequence features

A4I7X8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I7X8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	111	113	PF00082	0.605
CLV_PCSK_PC1ET2_1	111	113	PF00082	0.605
CLV_PCSK_SKI1_1	98	102	PF00082	0.657
DEG_APCC_DBOX_1	129	137	PF00400	0.633
DEG_SCF_FBW7_1	206	212	PF00400	0.601
DEG_SPOP_SBC_1	52	56	PF00917	0.547
DOC_CKS1_1	206	211	PF01111	0.533
DOC_PP4_FxxP_1	200	203	PF00568	0.628
DOC_USP7_MATH_1	120	124	PF00917	0.535
DOC_USP7_MATH_1	153	157	PF00917	0.636
DOC_USP7_MATH_1	186	190	PF00917	0.645
DOC_USP7_MATH_1	201	205	PF00917	0.516
DOC_USP7_MATH_1	224	228	PF00917	0.633
DOC_USP7_MATH_1	229	233	PF00917	0.571
DOC_USP7_MATH_1	34	38	PF00917	0.555
DOC_USP7_MATH_1	45	49	PF00917	0.567
DOC_USP7_MATH_1	53	57	PF00917	0.658
DOC_USP7_MATH_2	179	185	PF00917	0.622
DOC_USP7_UBL2_3	234	238	PF12436	0.604
DOC_USP7_UBL2_3	245	249	PF12436	0.445
DOC_WW_Pin1_4	122	127	PF00397	0.564
DOC_WW_Pin1_4	156	161	PF00397	0.623
DOC_WW_Pin1_4	175	180	PF00397	0.469
DOC_WW_Pin1_4	188	193	PF00397	0.592
DOC_WW_Pin1_4	195	200	PF00397	0.566
DOC_WW_Pin1_4	205	210	PF00397	0.534
DOC_WW_Pin1_4	37	42	PF00397	0.756
DOC_WW_Pin1_4	65	70	PF00397	0.717
LIG_14-3-3_CanoR_1	130	134	PF00244	0.646
LIG_14-3-3_CanoR_1	155	160	PF00244	0.563
LIG_14-3-3_CanoR_1	185	195	PF00244	0.610
LIG_14-3-3_CanoR_1	27	36	PF00244	0.529
LIG_14-3-3_CanoR_1	67	76	PF00244	0.704
LIG_Actin_WH2_2	95	113	PF00022	0.574
LIG_BIR_II_1	1	5	PF00653	0.606
LIG_BRCT_BRCA1_1	183	187	PF00533	0.541
LIG_BRCT_BRCA1_1	239	243	PF00533	0.439
LIG_BRCT_BRCA1_2	239	245	PF00533	0.439
LIG_FHA_1	167	173	PF00498	0.660
LIG_FHA_1	206	212	PF00498	0.604
LIG_FHA_1	75	81	PF00498	0.676
LIG_FHA_2	176	182	PF00498	0.633
LIG_FHA_2	188	194	PF00498	0.624
LIG_FHA_2	217	223	PF00498	0.542
LIG_LIR_Apic_2	198	203	PF02991	0.625
LIG_LIR_Gen_1	240	247	PF02991	0.444
LIG_LIR_Nem_3	37	42	PF02991	0.588
LIG_MLH1_MIPbox_1	239	243	PF16413	0.439
LIG_NRP_CendR_1	249	250	PF00754	0.568
LIG_PCNA_PIPBox_1	236	245	PF02747	0.446
LIG_PCNA_yPIPBox_3	234	243	PF02747	0.463
LIG_REV1ctd_RIR_1	240	249	PF16727	0.444
LIG_SH3_3	15	21	PF00018	0.655
LIG_SH3_3	189	195	PF00018	0.615
LIG_SH3_3	218	224	PF00018	0.684
LIG_SH3_3	73	79	PF00018	0.573
LIG_SUMO_SIM_anti_2	97	103	PF11976	0.542
LIG_TRAF2_1	162	165	PF00917	0.753
MOD_CDK_SPxxK_3	175	182	PF00069	0.756
MOD_CK1_1	13	19	PF00069	0.524
MOD_CK1_1	156	162	PF00069	0.613
MOD_CK1_1	168	174	PF00069	0.641
MOD_CK1_1	227	233	PF00069	0.671
MOD_CK1_1	37	43	PF00069	0.615
MOD_CK1_1	48	54	PF00069	0.687
MOD_CK1_1	68	74	PF00069	0.421
MOD_CK2_1	110	116	PF00069	0.584
MOD_CK2_1	175	181	PF00069	0.655
MOD_CK2_1	187	193	PF00069	0.625
MOD_CK2_1	211	217	PF00069	0.636
MOD_CK2_1	27	33	PF00069	0.704
MOD_GlcNHglycan	112	115	PF01048	0.610
MOD_GlcNHglycan	15	18	PF01048	0.763
MOD_GlcNHglycan	151	154	PF01048	0.690
MOD_GlcNHglycan	203	206	PF01048	0.678
MOD_GlcNHglycan	211	214	PF01048	0.658
MOD_GlcNHglycan	70	73	PF01048	0.613
MOD_GSK3_1	138	145	PF00069	0.778
MOD_GSK3_1	149	156	PF00069	0.622
MOD_GSK3_1	164	171	PF00069	0.671
MOD_GSK3_1	195	202	PF00069	0.641
MOD_GSK3_1	205	212	PF00069	0.630
MOD_GSK3_1	223	230	PF00069	0.614
MOD_GSK3_1	237	244	PF00069	0.452
MOD_GSK3_1	48	55	PF00069	0.671
MOD_N-GLC_1	141	146	PF02516	0.759
MOD_NEK2_1	11	16	PF00069	0.641
MOD_NEK2_1	166	171	PF00069	0.592
MOD_NEK2_1	187	192	PF00069	0.537
MOD_NEK2_1	211	216	PF00069	0.684
MOD_NEK2_1	94	99	PF00069	0.555
MOD_PIKK_1	143	149	PF00454	0.587
MOD_PIKK_1	227	233	PF00454	0.671
MOD_PIKK_1	59	65	PF00454	0.516
MOD_PK_1	103	109	PF00069	0.560
MOD_PKA_2	129	135	PF00069	0.645
MOD_PKA_2	181	187	PF00069	0.688
MOD_Plk_1	216	222	PF00069	0.637
MOD_Plk_4	103	109	PF00069	0.560
MOD_ProDKin_1	122	128	PF00069	0.561
MOD_ProDKin_1	156	162	PF00069	0.735
MOD_ProDKin_1	175	181	PF00069	0.499
MOD_ProDKin_1	188	194	PF00069	0.593
MOD_ProDKin_1	195	201	PF00069	0.565
MOD_ProDKin_1	205	211	PF00069	0.534
MOD_ProDKin_1	37	43	PF00069	0.758
MOD_ProDKin_1	65	71	PF00069	0.715

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P9J6	Leptomonas seymouri	34%	99%
A0A3S5IRE5	Trypanosoma rangeli	26%	100%
A0A3S7X5K9	Leishmania donovani	98%	100%
E9B2T9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
Q4Q5B7	Leishmania major	86%	100%