LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

PPR_long domain-containing protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
PPR_long domain-containing protein
Gene product:
Pentatricopeptide repeat domain/PPR repeat/PPR repeat family - putative
Species:
Leishmania infantum
UniProt:
A4I7T8_LEIIN
TriTrypDb:
LINF_320017800
Length:
801

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0031974 membrane-enclosed lumen 2 1
GO:0031981 nuclear lumen 5 1
GO:0032838 plasma membrane bounded cell projection cytoplasm 4 1
GO:0043233 organelle lumen 3 1
GO:0070013 intracellular organelle lumen 4 1
GO:0097014 ciliary plasm 5 1
GO:0099568 cytoplasmic region 3 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A4I7T8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I7T8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 15 17 PF00675 0.567
CLV_NRD_NRD_1 301 303 PF00675 0.475
CLV_NRD_NRD_1 381 383 PF00675 0.730
CLV_NRD_NRD_1 453 455 PF00675 0.582
CLV_NRD_NRD_1 709 711 PF00675 0.528
CLV_PCSK_KEX2_1 101 103 PF00082 0.532
CLV_PCSK_KEX2_1 14 16 PF00082 0.486
CLV_PCSK_KEX2_1 301 303 PF00082 0.482
CLV_PCSK_KEX2_1 5 7 PF00082 0.623
CLV_PCSK_KEX2_1 709 711 PF00082 0.496
CLV_PCSK_PC1ET2_1 101 103 PF00082 0.532
CLV_PCSK_PC1ET2_1 5 7 PF00082 0.647
CLV_PCSK_SKI1_1 101 105 PF00082 0.504
CLV_PCSK_SKI1_1 145 149 PF00082 0.449
CLV_PCSK_SKI1_1 151 155 PF00082 0.351
CLV_PCSK_SKI1_1 36 40 PF00082 0.698
CLV_PCSK_SKI1_1 476 480 PF00082 0.414
CLV_PCSK_SKI1_1 491 495 PF00082 0.471
CLV_PCSK_SKI1_1 552 556 PF00082 0.466
CLV_PCSK_SKI1_1 619 623 PF00082 0.479
CLV_PCSK_SKI1_1 709 713 PF00082 0.425
CLV_PCSK_SKI1_1 771 775 PF00082 0.484
CLV_PCSK_SKI1_1 780 784 PF00082 0.458
DEG_APCC_DBOX_1 770 778 PF00400 0.521
DEG_APCC_KENBOX_2 123 127 PF00400 0.548
DEG_Nend_Nbox_1 1 3 PF02207 0.629
DEG_SPOP_SBC_1 377 381 PF00917 0.580
DOC_CKS1_1 495 500 PF01111 0.526
DOC_CKS1_1 783 788 PF01111 0.588
DOC_CYCLIN_RxL_1 777 785 PF00134 0.519
DOC_MAPK_gen_1 454 460 PF00069 0.602
DOC_MAPK_gen_1 5 13 PF00069 0.676
DOC_MAPK_MEF2A_6 624 633 PF00069 0.465
DOC_PP1_RVXF_1 474 481 PF00149 0.542
DOC_PP1_SILK_1 341 346 PF00149 0.301
DOC_PP1_SILK_1 728 733 PF00149 0.436
DOC_PP4_FxxP_1 23 26 PF00568 0.668
DOC_PP4_FxxP_1 783 786 PF00568 0.506
DOC_USP7_MATH_1 377 381 PF00917 0.674
DOC_USP7_MATH_1 548 552 PF00917 0.462
DOC_USP7_MATH_1 591 595 PF00917 0.566
DOC_USP7_MATH_1 644 648 PF00917 0.639
DOC_USP7_MATH_1 65 69 PF00917 0.625
DOC_USP7_MATH_1 756 760 PF00917 0.546
DOC_WW_Pin1_4 494 499 PF00397 0.547
DOC_WW_Pin1_4 604 609 PF00397 0.423
DOC_WW_Pin1_4 782 787 PF00397 0.585
LIG_14-3-3_CanoR_1 105 112 PF00244 0.507
LIG_14-3-3_CanoR_1 83 91 PF00244 0.510
LIG_Actin_WH2_2 223 238 PF00022 0.455
LIG_Actin_WH2_2 464 481 PF00022 0.352
LIG_APCC_ABBA_1 112 117 PF00400 0.392
LIG_APCC_ABBA_1 224 229 PF00400 0.393
LIG_APCC_ABBA_1 353 358 PF00400 0.507
LIG_APCC_ABBAyCdc20_2 66 72 PF00400 0.627
LIG_BIR_III_4 767 771 PF00653 0.558
LIG_Clathr_ClatBox_1 466 470 PF01394 0.522
LIG_eIF4E_1 149 155 PF01652 0.377
LIG_FHA_1 187 193 PF00498 0.467
LIG_FHA_1 221 227 PF00498 0.389
LIG_FHA_1 361 367 PF00498 0.577
LIG_FHA_1 44 50 PF00498 0.537
LIG_FHA_1 536 542 PF00498 0.403
LIG_FHA_1 559 565 PF00498 0.525
LIG_FHA_1 574 580 PF00498 0.402
LIG_FHA_1 758 764 PF00498 0.442
LIG_FHA_1 93 99 PF00498 0.400
LIG_FHA_2 111 117 PF00498 0.507
LIG_FHA_2 280 286 PF00498 0.378
LIG_FHA_2 37 43 PF00498 0.662
LIG_FHA_2 731 737 PF00498 0.532
LIG_GBD_Chelix_1 317 325 PF00786 0.452
LIG_LIR_Apic_2 20 26 PF02991 0.642
LIG_LIR_Gen_1 113 123 PF02991 0.224
LIG_LIR_Gen_1 134 142 PF02991 0.356
LIG_LIR_Gen_1 161 171 PF02991 0.407
LIG_LIR_Gen_1 206 215 PF02991 0.364
LIG_LIR_Gen_1 229 239 PF02991 0.358
LIG_LIR_Gen_1 241 249 PF02991 0.267
LIG_LIR_Gen_1 256 265 PF02991 0.308
LIG_LIR_Gen_1 275 283 PF02991 0.198
LIG_LIR_Gen_1 44 55 PF02991 0.512
LIG_LIR_Gen_1 518 527 PF02991 0.529
LIG_LIR_Gen_1 557 567 PF02991 0.516
LIG_LIR_Gen_1 57 65 PF02991 0.319
LIG_LIR_Gen_1 690 699 PF02991 0.485
LIG_LIR_Gen_1 93 103 PF02991 0.375
LIG_LIR_Nem_3 113 118 PF02991 0.207
LIG_LIR_Nem_3 134 139 PF02991 0.353
LIG_LIR_Nem_3 161 166 PF02991 0.429
LIG_LIR_Nem_3 169 175 PF02991 0.335
LIG_LIR_Nem_3 206 210 PF02991 0.371
LIG_LIR_Nem_3 229 235 PF02991 0.371
LIG_LIR_Nem_3 241 245 PF02991 0.255
LIG_LIR_Nem_3 256 262 PF02991 0.308
LIG_LIR_Nem_3 275 280 PF02991 0.198
LIG_LIR_Nem_3 350 356 PF02991 0.469
LIG_LIR_Nem_3 44 50 PF02991 0.537
LIG_LIR_Nem_3 514 520 PF02991 0.459
LIG_LIR_Nem_3 57 63 PF02991 0.330
LIG_LIR_Nem_3 673 679 PF02991 0.479
LIG_LIR_Nem_3 689 695 PF02991 0.428
LIG_LIR_Nem_3 93 99 PF02991 0.377
LIG_NRBOX 463 469 PF00104 0.491
LIG_PALB2_WD40_1 628 636 PF16756 0.515
LIG_Pex14_1 331 335 PF04695 0.450
LIG_PTB_Apo_2 147 154 PF02174 0.540
LIG_Rb_pABgroove_1 109 117 PF01858 0.480
LIG_REV1ctd_RIR_1 618 628 PF16727 0.534
LIG_SH2_CRK 136 140 PF00017 0.377
LIG_SH2_CRK 156 160 PF00017 0.414
LIG_SH2_CRK 172 176 PF00017 0.259
LIG_SH2_CRK 207 211 PF00017 0.371
LIG_SH2_CRK 242 246 PF00017 0.343
LIG_SH2_CRK 277 281 PF00017 0.308
LIG_SH2_CRK 47 51 PF00017 0.539
LIG_SH2_CRK 614 618 PF00017 0.443
LIG_SH2_CRK 656 660 PF00017 0.413
LIG_SH2_CRK 727 731 PF00017 0.356
LIG_SH2_CRK 743 747 PF00017 0.557
LIG_SH2_CRK 784 788 PF00017 0.597
LIG_SH2_CRK 96 100 PF00017 0.369
LIG_SH2_GRB2like 232 235 PF00017 0.378
LIG_SH2_NCK_1 149 153 PF00017 0.408
LIG_SH2_NCK_1 255 259 PF00017 0.254
LIG_SH2_NCK_1 567 571 PF00017 0.527
LIG_SH2_NCK_1 669 673 PF00017 0.499
LIG_SH2_NCK_1 784 788 PF00017 0.597
LIG_SH2_SRC 47 50 PF00017 0.421
LIG_SH2_SRC 545 548 PF00017 0.462
LIG_SH2_STAP1 220 224 PF00017 0.388
LIG_SH2_STAP1 255 259 PF00017 0.308
LIG_SH2_STAP1 56 60 PF00017 0.397
LIG_SH2_STAP1 560 564 PF00017 0.473
LIG_SH2_STAP1 567 571 PF00017 0.518
LIG_SH2_STAP1 656 660 PF00017 0.472
LIG_SH2_STAT5 178 181 PF00017 0.466
LIG_SH2_STAT5 232 235 PF00017 0.468
LIG_SH2_STAT5 279 282 PF00017 0.368
LIG_SH2_STAT5 290 293 PF00017 0.371
LIG_SH2_STAT5 335 338 PF00017 0.480
LIG_SH2_STAT5 443 446 PF00017 0.479
LIG_SH2_STAT5 56 59 PF00017 0.407
LIG_SH2_STAT5 560 563 PF00017 0.479
LIG_SH2_STAT5 656 659 PF00017 0.384
LIG_SH2_STAT5 663 666 PF00017 0.347
LIG_SH2_STAT5 784 787 PF00017 0.576
LIG_SH3_3 783 789 PF00018 0.573
LIG_SUMO_SIM_par_1 279 285 PF11976 0.416
LIG_SUMO_SIM_par_1 465 470 PF11976 0.520
LIG_TRAF2_1 219 222 PF00917 0.508
LIG_TRAF2_1 572 575 PF00917 0.557
LIG_TRFH_1 163 167 PF08558 0.517
LIG_TYR_ITAM 229 245 PF00017 0.378
LIG_TYR_ITIM 154 159 PF00017 0.400
LIG_TYR_ITIM 230 235 PF00017 0.378
LIG_TYR_ITIM 725 730 PF00017 0.472
LIG_UBA3_1 111 119 PF00899 0.444
LIG_UBA3_1 191 196 PF00899 0.477
LIG_UBA3_1 230 236 PF00899 0.378
MOD_CK1_1 241 247 PF00069 0.396
MOD_CK1_1 378 384 PF00069 0.772
MOD_CK1_1 456 462 PF00069 0.580
MOD_CK1_1 558 564 PF00069 0.462
MOD_CK1_1 607 613 PF00069 0.364
MOD_CK1_1 688 694 PF00069 0.516
MOD_CK2_1 279 285 PF00069 0.429
MOD_CK2_1 515 521 PF00069 0.503
MOD_CK2_1 65 71 PF00069 0.641
MOD_CK2_1 680 686 PF00069 0.570
MOD_CK2_1 730 736 PF00069 0.420
MOD_GlcNHglycan 144 148 PF01048 0.525
MOD_GlcNHglycan 216 219 PF01048 0.453
MOD_GlcNHglycan 297 300 PF01048 0.637
MOD_GlcNHglycan 448 452 PF01048 0.559
MOD_GlcNHglycan 455 458 PF01048 0.489
MOD_GlcNHglycan 636 639 PF01048 0.519
MOD_GlcNHglycan 642 645 PF01048 0.586
MOD_GlcNHglycan 646 649 PF01048 0.498
MOD_GSK3_1 291 298 PF00069 0.554
MOD_GSK3_1 32 39 PF00069 0.711
MOD_GSK3_1 339 346 PF00069 0.497
MOD_GSK3_1 456 463 PF00069 0.577
MOD_GSK3_1 511 518 PF00069 0.329
MOD_GSK3_1 600 607 PF00069 0.558
MOD_GSK3_1 640 647 PF00069 0.614
MOD_GSK3_1 726 733 PF00069 0.429
MOD_LATS_1 81 87 PF00433 0.547
MOD_N-GLC_1 125 130 PF02516 0.511
MOD_N-GLC_1 460 465 PF02516 0.459
MOD_N-GLC_1 604 609 PF02516 0.535
MOD_N-GLC_1 644 649 PF02516 0.652
MOD_NEK2_1 1 6 PF00069 0.733
MOD_NEK2_1 214 219 PF00069 0.438
MOD_NEK2_1 317 322 PF00069 0.350
MOD_NEK2_1 453 458 PF00069 0.534
MOD_NEK2_1 460 465 PF00069 0.405
MOD_NEK2_1 555 560 PF00069 0.408
MOD_NEK2_1 613 618 PF00069 0.473
MOD_NEK2_2 110 115 PF00069 0.529
MOD_NEK2_2 220 225 PF00069 0.396
MOD_NEK2_2 65 70 PF00069 0.619
MOD_PIKK_1 90 96 PF00454 0.555
MOD_PK_1 339 345 PF00069 0.513
MOD_PKA_1 101 107 PF00069 0.477
MOD_PKA_2 101 107 PF00069 0.533
MOD_PKA_2 291 297 PF00069 0.550
MOD_PKA_2 300 306 PF00069 0.469
MOD_PKA_2 453 459 PF00069 0.596
MOD_PKA_2 634 640 PF00069 0.575
MOD_PKB_1 14 22 PF00069 0.571
MOD_Plk_1 124 130 PF00069 0.490
MOD_Plk_1 143 149 PF00069 0.278
MOD_Plk_1 220 226 PF00069 0.411
MOD_Plk_1 43 49 PF00069 0.612
MOD_Plk_1 460 466 PF00069 0.553
MOD_Plk_1 573 579 PF00069 0.470
MOD_Plk_1 757 763 PF00069 0.532
MOD_Plk_4 132 138 PF00069 0.499
MOD_Plk_4 171 177 PF00069 0.357
MOD_Plk_4 186 192 PF00069 0.388
MOD_Plk_4 209 215 PF00069 0.426
MOD_Plk_4 241 247 PF00069 0.393
MOD_Plk_4 317 323 PF00069 0.368
MOD_Plk_4 339 345 PF00069 0.397
MOD_Plk_4 555 561 PF00069 0.449
MOD_Plk_4 591 597 PF00069 0.548
MOD_Plk_4 613 619 PF00069 0.510
MOD_Plk_4 654 660 PF00069 0.512
MOD_Plk_4 688 694 PF00069 0.546
MOD_Plk_4 726 732 PF00069 0.477
MOD_ProDKin_1 494 500 PF00069 0.539
MOD_ProDKin_1 604 610 PF00069 0.421
MOD_ProDKin_1 782 788 PF00069 0.583
MOD_SUMO_for_1 118 121 PF00179 0.438
MOD_SUMO_rev_2 116 120 PF00179 0.473
MOD_SUMO_rev_2 193 198 PF00179 0.515
TRG_DiLeu_BaEn_1 134 139 PF01217 0.475
TRG_DiLeu_BaEn_1 161 166 PF01217 0.515
TRG_DiLeu_BaEn_1 490 495 PF01217 0.475
TRG_DiLeu_BaEn_3 44 50 PF01217 0.494
TRG_DiLeu_BaEn_4 193 199 PF01217 0.522
TRG_ENDOCYTIC_2 115 118 PF00928 0.388
TRG_ENDOCYTIC_2 136 139 PF00928 0.390
TRG_ENDOCYTIC_2 156 159 PF00928 0.179
TRG_ENDOCYTIC_2 172 175 PF00928 0.337
TRG_ENDOCYTIC_2 207 210 PF00928 0.357
TRG_ENDOCYTIC_2 232 235 PF00928 0.362
TRG_ENDOCYTIC_2 242 245 PF00928 0.296
TRG_ENDOCYTIC_2 277 280 PF00928 0.308
TRG_ENDOCYTIC_2 356 359 PF00928 0.402
TRG_ENDOCYTIC_2 47 50 PF00928 0.570
TRG_ENDOCYTIC_2 520 523 PF00928 0.519
TRG_ENDOCYTIC_2 560 563 PF00928 0.399
TRG_ENDOCYTIC_2 614 617 PF00928 0.361
TRG_ENDOCYTIC_2 656 659 PF00928 0.390
TRG_ENDOCYTIC_2 669 672 PF00928 0.361
TRG_ENDOCYTIC_2 692 695 PF00928 0.396
TRG_ENDOCYTIC_2 727 730 PF00928 0.358
TRG_ENDOCYTIC_2 743 746 PF00928 0.438
TRG_ENDOCYTIC_2 96 99 PF00928 0.358
TRG_ER_diArg_1 13 16 PF00400 0.605
TRG_ER_diArg_1 301 304 PF00400 0.500
TRG_ER_diArg_1 708 710 PF00400 0.516
TRG_Pf-PMV_PEXEL_1 732 736 PF00026 0.471

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IAW5 Leptomonas seymouri 57% 100%
A0A0S4JD08 Bodo saltans 33% 95%
A0A1X0NW71 Trypanosomatidae 40% 100%
A0A3S7X5H9 Leishmania donovani 100% 100%
A0A422P1H7 Trypanosoma rangeli 39% 100%
A4HKA8 Leishmania braziliensis 80% 100%
B8Y6I0 Zea mays 20% 100%
D0A9Z8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 97%
E9B2P6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q0WPZ6 Arabidopsis thaliana 20% 92%
Q4Q5G1 Leishmania major 95% 100%
Q76C99 Oryza sativa subsp. indica 21% 100%
Q9FIT7 Arabidopsis thaliana 22% 82%
Q9LSL9 Arabidopsis thaliana 21% 88%
Q9LYZ9 Arabidopsis thaliana 21% 98%
Q9SH60 Arabidopsis thaliana 23% 100%
Q9SS81 Arabidopsis thaliana 21% 100%
V5BL80 Trypanosoma cruzi 43% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS