LeishMANIAdb
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Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Protein kinase domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I7T6_LEIIN
TriTrypDb:
LINF_320017600
Length:
566

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I7T6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I7T6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 261 265 PF00656 0.555
CLV_C14_Caspase3-7 389 393 PF00656 0.558
CLV_C14_Caspase3-7 451 455 PF00656 0.676
CLV_NRD_NRD_1 103 105 PF00675 0.662
CLV_NRD_NRD_1 352 354 PF00675 0.661
CLV_NRD_NRD_1 442 444 PF00675 0.633
CLV_NRD_NRD_1 446 448 PF00675 0.611
CLV_NRD_NRD_1 517 519 PF00675 0.633
CLV_PCSK_KEX2_1 103 105 PF00082 0.661
CLV_PCSK_KEX2_1 267 269 PF00082 0.572
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P995 Leptomonas seymouri 30% 100%
A0A3S7X5D7 Leishmania donovani 99% 100%
A4HKA6 Leishmania braziliensis 52% 97%
E9B2P4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 75% 99%
Q4Q5G3 Leishmania major 83% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS