Phage protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Phage protein

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I7N5_LEIIN

TriTrypDb:

LINF_320010000

Length:

101

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I7N5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I7N5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	36	38	PF00675	0.399
CLV_PCSK_KEX2_1	35	37	PF00082	0.594
CLV_PCSK_PC1ET2_1	35	37	PF00082	0.594
DEG_APCC_DBOX_1	58	66	PF00400	0.525
DEG_Nend_UBRbox_1	1	4	PF02207	0.564
DOC_MAPK_gen_1	49	58	PF00069	0.398
DOC_PP1_RVXF_1	6	13	PF00149	0.528
DOC_USP7_MATH_1	90	94	PF00917	0.601
DOC_WW_Pin1_4	86	91	PF00397	0.586
LIG_14-3-3_CanoR_1	37	43	PF00244	0.403
LIG_BRCT_BRCA1_1	65	69	PF00533	0.577
LIG_FHA_1	5	11	PF00498	0.514
LIG_FHA_1	53	59	PF00498	0.590
LIG_LIR_Gen_1	25	34	PF02991	0.511
LIG_LIR_Gen_1	78	88	PF02991	0.499
LIG_LIR_Nem_3	25	31	PF02991	0.498
LIG_LIR_Nem_3	78	84	PF02991	0.402
LIG_PCNA_yPIPBox_3	24	37	PF02747	0.573
LIG_SH2_CRK	81	85	PF00017	0.340
LIG_SH2_NCK_1	28	32	PF00017	0.511
LIG_SH3_3	7	13	PF00018	0.433
MOD_CDK_SPK_2	86	91	PF00069	0.503
MOD_CK1_1	40	46	PF00069	0.594
MOD_CK1_1	76	82	PF00069	0.623
MOD_CK1_1	93	99	PF00069	0.569
MOD_CK2_1	14	20	PF00069	0.545
MOD_CK2_1	47	53	PF00069	0.509
MOD_CK2_1	86	92	PF00069	0.594
MOD_GlcNHglycan	77	81	PF01048	0.576
MOD_GSK3_1	86	93	PF00069	0.602
MOD_N-GLC_1	93	98	PF02516	0.448
MOD_NEK2_1	1	6	PF00069	0.552
MOD_NEK2_1	47	52	PF00069	0.497
MOD_PKA_2	90	96	PF00069	0.617
MOD_Plk_1	76	82	PF00069	0.653
MOD_Plk_1	93	99	PF00069	0.452
MOD_Plk_4	52	58	PF00069	0.533
MOD_Plk_4	93	99	PF00069	0.679
MOD_ProDKin_1	86	92	PF00069	0.594
TRG_ENDOCYTIC_2	28	31	PF00928	0.499
TRG_ENDOCYTIC_2	81	84	PF00928	0.451
TRG_ENDOCYTIC_2	85	88	PF00928	0.420

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0P7X3	Trypanosomatidae	33%	85%
A0A3S7X569	Leishmania donovani	100%	100%
A0A422N1C7	Trypanosoma rangeli	31%	80%
D0A0C0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	81%
E9AIU8	Leishmania braziliensis	83%	100%
E9B2H0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4Q5N6	Leishmania major	91%	100%