Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I796_LEIIN

TriTrypDb:

LINF_310037900

Length:

247

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I796

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I796

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	126	130	PF00656	0.695
CLV_NRD_NRD_1	108	110	PF00675	0.563
CLV_NRD_NRD_1	214	216	PF00675	0.589
CLV_NRD_NRD_1	245	247	PF00675	0.758
CLV_NRD_NRD_1	91	93	PF00675	0.475
CLV_PCSK_FUR_1	105	109	PF00082	0.509
CLV_PCSK_KEX2_1	105	107	PF00082	0.567
CLV_PCSK_KEX2_1	108	110	PF00082	0.563
CLV_PCSK_KEX2_1	214	216	PF00082	0.589
CLV_PCSK_KEX2_1	245	247	PF00082	0.758
CLV_PCSK_KEX2_1	91	93	PF00082	0.475
CLV_PCSK_SKI1_1	42	46	PF00082	0.431
DEG_APCC_DBOX_1	41	49	PF00400	0.424
DEG_SCF_FBW7_1	142	149	PF00400	0.651
DEG_SPOP_SBC_1	184	188	PF00917	0.630
DOC_MAPK_MEF2A_6	147	154	PF00069	0.556
DOC_WW_Pin1_4	142	147	PF00397	0.630
DOC_WW_Pin1_4	170	175	PF00397	0.669
DOC_WW_Pin1_4	185	190	PF00397	0.665
DOC_WW_Pin1_4	4	9	PF00397	0.638
DOC_WW_Pin1_4	53	58	PF00397	0.596
LIG_14-3-3_CanoR_1	17	26	PF00244	0.450
LIG_14-3-3_CanoR_1	235	243	PF00244	0.599
LIG_14-3-3_CanoR_1	50	58	PF00244	0.531
LIG_14-3-3_CanoR_1	99	105	PF00244	0.538
LIG_14-3-3_CterR_2	245	247	PF00244	0.620
LIG_BRCT_BRCA1_1	65	69	PF00533	0.630
LIG_eIF4E_1	41	47	PF01652	0.419
LIG_FHA_2	88	94	PF00498	0.497
LIG_MYND_1	142	146	PF01753	0.598
LIG_SH2_STAT5	51	54	PF00017	0.497
LIG_SH3_2	210	215	PF14604	0.583
LIG_SH3_3	207	213	PF00018	0.604
LIG_SUMO_SIM_par_1	148	155	PF11976	0.553
LIG_SUMO_SIM_par_1	180	188	PF11976	0.634
MOD_CDK_SPK_2	142	147	PF00069	0.654
MOD_CDK_SPK_2	170	175	PF00069	0.604
MOD_CDK_SPxK_1	4	10	PF00069	0.634
MOD_CK1_1	170	176	PF00069	0.676
MOD_CK1_1	228	234	PF00069	0.695
MOD_CK1_1	33	39	PF00069	0.436
MOD_CK1_1	56	62	PF00069	0.698
MOD_CK1_1	67	73	PF00069	0.439
MOD_CK2_1	67	73	PF00069	0.637
MOD_CK2_1	87	93	PF00069	0.464
MOD_Cter_Amidation	243	246	PF01082	0.668
MOD_GlcNHglycan	115	118	PF01048	0.613
MOD_GlcNHglycan	165	168	PF01048	0.648
MOD_GlcNHglycan	19	22	PF01048	0.470
MOD_GlcNHglycan	205	208	PF01048	0.527
MOD_GlcNHglycan	230	233	PF01048	0.597
MOD_GlcNHglycan	66	69	PF01048	0.651
MOD_GSK3_1	142	149	PF00069	0.812
MOD_GSK3_1	163	170	PF00069	0.589
MOD_GSK3_1	180	187	PF00069	0.698
MOD_GSK3_1	52	59	PF00069	0.583
MOD_GSK3_1	63	70	PF00069	0.515
MOD_N-GLC_1	184	189	PF02516	0.628
MOD_NEK2_1	163	168	PF00069	0.664
MOD_NEK2_1	52	57	PF00069	0.511
MOD_NEK2_1	84	89	PF00069	0.533
MOD_NEK2_2	100	105	PF00069	0.540
MOD_PIKK_1	236	242	PF00454	0.630
MOD_PKA_1	108	114	PF00069	0.514
MOD_PKA_2	108	114	PF00069	0.550
MOD_PKA_2	30	36	PF00069	0.443
MOD_PKB_1	106	114	PF00069	0.514
MOD_Plk_1	158	164	PF00069	0.606
MOD_ProDKin_1	142	148	PF00069	0.629
MOD_ProDKin_1	170	176	PF00069	0.669
MOD_ProDKin_1	185	191	PF00069	0.665
MOD_ProDKin_1	4	10	PF00069	0.634
MOD_ProDKin_1	53	59	PF00069	0.604
TRG_ER_diArg_1	104	107	PF00400	0.566
TRG_ER_diArg_1	213	215	PF00400	0.609
TRG_ER_diArg_1	217	220	PF00400	0.628
TRG_Pf-PMV_PEXEL_1	235	240	PF00026	0.605

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCN9	Leptomonas seymouri	39%	99%
A0A3Q8IGF1	Leishmania donovani	99%	100%
A4HJT0	Leishmania braziliensis	74%	100%
E9B291	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4Q5W7	Leishmania major	94%	100%