Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I787_LEIIN

TriTrypDb:

LINF_310037000

Length:

624

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A4I787

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I787

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	103	107	PF00656	0.628
CLV_C14_Caspase3-7	55	59	PF00656	0.609
CLV_C14_Caspase3-7	64	68	PF00656	0.543
CLV_NRD_NRD_1	11	13	PF00675	0.562
CLV_NRD_NRD_1	132	134	PF00675	0.654
CLV_NRD_NRD_1	139	141	PF00675	0.585
CLV_NRD_NRD_1	242	244	PF00675	0.548
CLV_NRD_NRD_1	250	252	PF00675	0.500
CLV_NRD_NRD_1	331	333	PF00675	0.513
CLV_NRD_NRD_1	423	425	PF00675	0.798

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IIU7	Leishmania donovani	100%	100%
A4HJS1	Leishmania braziliensis	69%	100%
E9B282	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q5X6	Leishmania major	91%	100%

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