Uncharacterized protein

Quick info Annotations Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I751_LEIIN

TriTrypDb:

LINF_310032800

Length:

194

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	yes	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 13
NetGPI	no	yes: 0, no: 13

Could not find GO cellular_component term for this entry.

Phosphorylation

Promastigote/Amastigote: 141

Expansion

Sequence features

A4I751

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I751

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	19	21	PF00675	0.495
CLV_PCSK_KEX2_1	19	21	PF00082	0.436
CLV_PCSK_SKI1_1	19	23	PF00082	0.456
CLV_PCSK_SKI1_1	61	65	PF00082	0.446
DEG_Nend_UBRbox_2	1	3	PF02207	0.424
DOC_CYCLIN_yCln2_LP_2	168	174	PF00134	0.487
DOC_MAPK_gen_1	16	24	PF00069	0.334
DOC_USP7_UBL2_3	60	64	PF12436	0.439
LIG_14-3-3_CanoR_1	101	105	PF00244	0.401
LIG_14-3-3_CanoR_1	19	25	PF00244	0.371
LIG_14-3-3_CanoR_1	48	53	PF00244	0.529
LIG_FHA_1	111	117	PF00498	0.489
LIG_FHA_1	157	163	PF00498	0.556
LIG_FHA_1	16	22	PF00498	0.447
LIG_FHA_1	92	98	PF00498	0.613
LIG_LIR_Gen_1	65	74	PF02991	0.526
LIG_Pex14_1	114	118	PF04695	0.414
LIG_SH2_STAT5	102	105	PF00017	0.520
MOD_CK1_1	133	139	PF00069	0.643
MOD_CK1_1	66	72	PF00069	0.473
MOD_CK2_1	65	71	PF00069	0.432
MOD_GlcNHglycan	91	94	PF01048	0.688
MOD_N-GLC_1	138	143	PF02516	0.536
MOD_NEK2_1	130	135	PF00069	0.482
MOD_NEK2_1	47	52	PF00069	0.466
MOD_NEK2_2	100	105	PF00069	0.464
MOD_PKA_2	100	106	PF00069	0.486
MOD_PKA_2	47	53	PF00069	0.409
MOD_Plk_1	138	144	PF00069	0.547
MOD_Plk_2-3	156	162	PF00069	0.585
MOD_Plk_4	110	116	PF00069	0.568
MOD_Plk_4	138	144	PF00069	0.547
TRG_DiLeu_BaEn_1	138	143	PF01217	0.511
TRG_DiLeu_BaEn_2	162	168	PF01217	0.560
TRG_ENDOCYTIC_2	121	124	PF00928	0.442
TRG_ENDOCYTIC_2	174	177	PF00928	0.459
TRG_ER_diArg_1	19	21	PF00400	0.556
TRG_ER_diArg_1	36	39	PF00400	0.401

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I730	Leptomonas seymouri	47%	99%
A0A0N1I8Q6	Leptomonas seymouri	24%	85%
A0A0N1PCW5	Leptomonas seymouri	23%	89%
A0A3Q8IF19	Leishmania donovani	23%	89%
A0A3Q8IKA6	Leishmania donovani	99%	100%
A4HJM8	Leishmania braziliensis	22%	100%
A4HJM9	Leishmania braziliensis	57%	100%
A4I750	Leishmania infantum	23%	100%
E9B244	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9B245	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%
Q4Q616	Leishmania major	83%	100%
Q4Q617	Leishmania major	23%	100%