Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I747_LEIIN

TriTrypDb:

LINF_310032400

Length:

203

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I747

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I747

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	27	31	PF00656	0.523
CLV_MEL_PAP_1	92	98	PF00089	0.534
CLV_NRD_NRD_1	66	68	PF00675	0.574
CLV_PCSK_FUR_1	64	68	PF00082	0.573
CLV_PCSK_KEX2_1	66	68	PF00082	0.574
CLV_PCSK_KEX2_1	94	96	PF00082	0.657
CLV_PCSK_PC1ET2_1	94	96	PF00082	0.607
DEG_SPOP_SBC_1	125	129	PF00917	0.655
DEG_SPOP_SBC_1	136	140	PF00917	0.525
DOC_CYCLIN_yClb3_PxF_3	83	89	PF00134	0.626
DOC_CYCLIN_yCln2_LP_2	78	84	PF00134	0.690
DOC_PP2B_LxvP_1	42	45	PF13499	0.606
DOC_USP7_MATH_1	125	129	PF00917	0.757
DOC_USP7_MATH_1	132	136	PF00917	0.493
DOC_USP7_MATH_1	153	157	PF00917	0.728
DOC_USP7_MATH_1	52	56	PF00917	0.676
DOC_WW_Pin1_4	70	75	PF00397	0.656
LIG_BIR_II_1	1	5	PF00653	0.690
LIG_BIR_III_2	30	34	PF00653	0.547
LIG_FHA_1	118	124	PF00498	0.639
LIG_FHA_1	136	142	PF00498	0.690
LIG_FHA_1	34	40	PF00498	0.605
LIG_LIR_Gen_1	140	151	PF02991	0.575
LIG_LIR_Gen_1	55	60	PF02991	0.567
LIG_LIR_Gen_1	88	96	PF02991	0.636
LIG_LIR_Gen_1	98	105	PF02991	0.624
LIG_LIR_Nem_3	140	146	PF02991	0.543
LIG_LIR_Nem_3	55	59	PF02991	0.570
LIG_LIR_Nem_3	88	92	PF02991	0.670
LIG_PDZ_Class_2	198	203	PF00595	0.573
LIG_SH2_STAT5	171	174	PF00017	0.535
LIG_SH3_3	42	48	PF00018	0.762
LIG_SH3_3	78	84	PF00018	0.640
LIG_WRC_WIRS_1	53	58	PF05994	0.566
LIG_WRC_WIRS_1	96	101	PF05994	0.712
LIG_WW_3	73	77	PF00397	0.699
MOD_CDC14_SPxK_1	73	76	PF00782	0.695
MOD_CDK_SPxK_1	70	76	PF00069	0.704
MOD_CK1_1	107	113	PF00069	0.651
MOD_CK1_1	124	130	PF00069	0.753
MOD_CK1_1	135	141	PF00069	0.641
MOD_CK1_1	55	61	PF00069	0.724
MOD_Cter_Amidation	64	67	PF01082	0.569
MOD_GlcNHglycan	123	126	PF01048	0.789
MOD_GlcNHglycan	49	52	PF01048	0.637
MOD_GSK3_1	104	111	PF00069	0.599
MOD_GSK3_1	117	124	PF00069	0.658
MOD_GSK3_1	132	139	PF00069	0.622
MOD_GSK3_1	55	62	PF00069	0.733
MOD_GSK3_1	6	13	PF00069	0.678
MOD_GSK3_1	66	73	PF00069	0.632
MOD_NEK2_1	10	15	PF00069	0.706
MOD_NEK2_1	108	113	PF00069	0.729
MOD_NEK2_1	121	126	PF00069	0.617
MOD_NEK2_1	59	64	PF00069	0.609
MOD_NEK2_2	52	57	PF00069	0.614
MOD_PIKK_1	82	88	PF00454	0.613
MOD_PKA_1	66	72	PF00069	0.582
MOD_PKA_2	66	72	PF00069	0.791
MOD_PKB_1	64	72	PF00069	0.630
MOD_Plk_1	116	122	PF00069	0.651
MOD_Plk_4	104	110	PF00069	0.651
MOD_Plk_4	55	61	PF00069	0.545
MOD_ProDKin_1	70	76	PF00069	0.656
MOD_SUMO_rev_2	174	181	PF00179	0.541
TRG_DiLeu_BaEn_1	104	109	PF01217	0.649
TRG_ER_diArg_1	64	67	PF00400	0.569

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X4V8	Leishmania donovani	99%	100%
A4HJM5	Leishmania braziliensis	63%	99%
E9B241	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%