LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Protein kinase domain-containing protein
Gene product:
hypothetical protein
Species:
Leishmania infantum
UniProt:
A4I702_LEIIN
TriTrypDb:
LINF_310030150
Length:
587

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I702
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I702

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 409 413 PF00656 0.628
CLV_C14_Caspase3-7 535 539 PF00656 0.571
CLV_C14_Caspase3-7 77 81 PF00656 0.582
CLV_NRD_NRD_1 224 226 PF00675 0.774
CLV_NRD_NRD_1 251 253 PF00675 0.633
CLV_NRD_NRD_1 262 264 PF00675 0.545
CLV_NRD_NRD_1 410 412 PF00675 0.640
CLV_NRD_NRD_1 556 558 PF00675 0.620
CLV_NRD_NRD_1 561 563 PF00675 0.609
CLV_PCSK_FUR_1 249 253 PF00082 0.629
CLV_PCSK_FUR_1 260 264 PF00082 0.525
CLV_PCSK_KEX2_1 224 226 PF00082 0.778
CLV_PCSK_KEX2_1 251 253 PF00082 0.633
CLV_PCSK_KEX2_1 262 264 PF00082 0.545
CLV_PCSK_KEX2_1 410 412 PF00082 0.658
CLV_PCSK_KEX2_1 508 510 PF00082 0.660
CLV_PCSK_KEX2_1 560 562 PF00082 0.601
CLV_PCSK_PC1ET2_1 508 510 PF00082 0.660
CLV_PCSK_PC7_1 557 563 PF00082 0.610
CLV_PCSK_SKI1_1 206 210 PF00082 0.644
CLV_PCSK_SKI1_1 45 49 PF00082 0.569
CLV_PCSK_SKI1_1 562 566 PF00082 0.614
DEG_SCF_FBW7_1 351 357 PF00400 0.628
DEG_SPOP_SBC_1 296 300 PF00917 0.601
DEG_SPOP_SBC_1 92 96 PF00917 0.597
DOC_CKS1_1 351 356 PF01111 0.633
DOC_CKS1_1 7 12 PF01111 0.592
DOC_CYCLIN_RxL_1 39 52 PF00134 0.569
DOC_MAPK_gen_1 15 23 PF00069 0.618
DOC_MAPK_gen_1 205 214 PF00069 0.614
DOC_MAPK_gen_1 260 268 PF00069 0.593
DOC_MAPK_gen_1 284 292 PF00069 0.601
DOC_MAPK_gen_1 557 566 PF00069 0.612
DOC_MAPK_HePTP_8 202 214 PF00069 0.569
DOC_MAPK_MEF2A_6 205 214 PF00069 0.575
DOC_MAPK_MEF2A_6 260 268 PF00069 0.593
DOC_USP7_MATH_1 154 158 PF00917 0.603
DOC_USP7_MATH_1 208 212 PF00917 0.689
DOC_USP7_MATH_1 217 221 PF00917 0.574
DOC_USP7_MATH_1 232 236 PF00917 0.527
DOC_USP7_MATH_1 258 262 PF00917 0.611
DOC_USP7_MATH_1 28 32 PF00917 0.595
DOC_USP7_MATH_1 302 306 PF00917 0.689
DOC_USP7_MATH_1 35 39 PF00917 0.496
DOC_USP7_MATH_1 354 358 PF00917 0.697
DOC_USP7_MATH_1 377 381 PF00917 0.647
DOC_USP7_MATH_1 488 492 PF00917 0.644
DOC_USP7_MATH_1 57 61 PF00917 0.592
DOC_USP7_MATH_1 571 575 PF00917 0.620
DOC_USP7_MATH_1 78 82 PF00917 0.730
DOC_USP7_MATH_1 92 96 PF00917 0.626
DOC_USP7_UBL2_3 205 209 PF12436 0.609
DOC_WW_Pin1_4 100 105 PF00397 0.690
DOC_WW_Pin1_4 169 174 PF00397 0.692
DOC_WW_Pin1_4 251 256 PF00397 0.669
DOC_WW_Pin1_4 339 344 PF00397 0.623
DOC_WW_Pin1_4 350 355 PF00397 0.566
DOC_WW_Pin1_4 364 369 PF00397 0.509
DOC_WW_Pin1_4 380 385 PF00397 0.703
DOC_WW_Pin1_4 414 419 PF00397 0.661
DOC_WW_Pin1_4 53 58 PF00397 0.652
DOC_WW_Pin1_4 569 574 PF00397 0.607
DOC_WW_Pin1_4 579 584 PF00397 0.552
DOC_WW_Pin1_4 6 11 PF00397 0.592
DOC_WW_Pin1_4 70 75 PF00397 0.701
DOC_WW_Pin1_4 93 98 PF00397 0.599
LIG_14-3-3_CanoR_1 131 137 PF00244 0.552
LIG_14-3-3_CanoR_1 187 193 PF00244 0.640
LIG_14-3-3_CanoR_1 224 229 PF00244 0.644
LIG_14-3-3_CanoR_1 277 285 PF00244 0.603
LIG_14-3-3_CanoR_1 293 297 PF00244 0.567
LIG_14-3-3_CanoR_1 335 343 PF00244 0.680
LIG_14-3-3_CanoR_1 373 377 PF00244 0.641
LIG_14-3-3_CanoR_1 49 54 PF00244 0.592
LIG_14-3-3_CanoR_1 560 565 PF00244 0.612
LIG_APCC_ABBA_1 266 271 PF00400 0.581
LIG_BRCT_BRCA1_1 365 369 PF00533 0.682
LIG_BRCT_BRCA1_1 72 76 PF00533 0.566
LIG_CSL_BTD_1 71 74 PF09270 0.595
LIG_CtBP_PxDLS_1 387 391 PF00389 0.578
LIG_FHA_1 193 199 PF00498 0.678
LIG_FHA_1 287 293 PF00498 0.600
LIG_FHA_1 561 567 PF00498 0.611
LIG_FHA_2 121 127 PF00498 0.567
LIG_FHA_2 156 162 PF00498 0.658
LIG_FHA_2 533 539 PF00498 0.574
LIG_LIR_Apic_2 500 506 PF02991 0.611
LIG_LIR_Apic_2 52 57 PF02991 0.578
LIG_LIR_Apic_2 523 528 PF02991 0.582
LIG_LIR_Gen_1 125 134 PF02991 0.558
LIG_LIR_Gen_1 437 446 PF02991 0.567
LIG_LIR_Nem_3 125 130 PF02991 0.596
LIG_LIR_Nem_3 356 361 PF02991 0.602
LIG_LIR_Nem_3 393 399 PF02991 0.620
LIG_LIR_Nem_3 437 442 PF02991 0.585
LIG_LIR_Nem_3 452 456 PF02991 0.539
LIG_MAD2 565 573 PF02301 0.580
LIG_Pex14_1 72 76 PF04695 0.566
LIG_SH2_CRK 485 489 PF00017 0.604
LIG_SH2_CRK 54 58 PF00017 0.582
LIG_SH2_GRB2like 503 506 PF00017 0.617
LIG_SH2_NCK_1 485 489 PF00017 0.604
LIG_SH2_NCK_1 54 58 PF00017 0.543
LIG_SH2_PTP2 503 506 PF00017 0.656
LIG_SH2_SRC 454 457 PF00017 0.608
LIG_SH2_SRC 503 506 PF00017 0.617
LIG_SH2_STAP1 143 147 PF00017 0.610
LIG_SH2_STAP1 318 322 PF00017 0.583
LIG_SH2_STAP1 451 455 PF00017 0.606
LIG_SH2_STAT5 441 444 PF00017 0.607
LIG_SH2_STAT5 503 506 PF00017 0.656
LIG_SH3_1 170 176 PF00018 0.624
LIG_SH3_1 252 258 PF00018 0.625
LIG_SH3_1 416 422 PF00018 0.620
LIG_SH3_2 255 260 PF14604 0.657
LIG_SH3_3 136 142 PF00018 0.638
LIG_SH3_3 144 150 PF00018 0.651
LIG_SH3_3 170 176 PF00018 0.776
LIG_SH3_3 211 217 PF00018 0.623
LIG_SH3_3 234 240 PF00018 0.636
LIG_SH3_3 252 258 PF00018 0.839
LIG_SH3_3 381 387 PF00018 0.615
LIG_SH3_3 416 422 PF00018 0.620
LIG_SH3_3 577 583 PF00018 0.568
LIG_SUMO_SIM_anti_2 319 324 PF11976 0.540
LIG_SUMO_SIM_par_1 328 334 PF11976 0.576
LIG_TRAF2_1 117 120 PF00917 0.624
LIG_TRAF2_1 476 479 PF00917 0.645
LIG_WRC_WIRS_1 450 455 PF05994 0.604
LIG_WW_3 167 171 PF00397 0.628
LIG_WW_3 187 191 PF00397 0.642
MOD_CDK_SPK_2 341 346 PF00069 0.655
MOD_CDK_SPxK_1 169 175 PF00069 0.666
MOD_CDK_SPxxK_3 339 346 PF00069 0.649
MOD_CDK_SPxxK_3 93 100 PF00069 0.603
MOD_CK1_1 227 233 PF00069 0.633
MOD_CK1_1 295 301 PF00069 0.750
MOD_CK1_1 338 344 PF00069 0.676
MOD_CK1_1 363 369 PF00069 0.686
MOD_CK1_1 372 378 PF00069 0.649
MOD_CK1_1 380 386 PF00069 0.654
MOD_CK1_1 400 406 PF00069 0.720
MOD_CK1_1 432 438 PF00069 0.617
MOD_CK1_1 457 463 PF00069 0.645
MOD_CK1_1 491 497 PF00069 0.597
MOD_CK1_1 536 542 PF00069 0.601
MOD_CK1_1 56 62 PF00069 0.642
MOD_CK1_1 574 580 PF00069 0.569
MOD_CK1_1 6 12 PF00069 0.593
MOD_CK1_1 70 76 PF00069 0.484
MOD_CK2_1 155 161 PF00069 0.674
MOD_CK2_1 383 389 PF00069 0.725
MOD_CK2_1 472 478 PF00069 0.649
MOD_CK2_1 504 510 PF00069 0.701
MOD_GlcNHglycan 219 222 PF01048 0.698
MOD_GlcNHglycan 286 289 PF01048 0.631
MOD_GlcNHglycan 337 340 PF01048 0.694
MOD_GlcNHglycan 362 365 PF01048 0.750
MOD_GlcNHglycan 374 377 PF01048 0.786
MOD_GlcNHglycan 379 382 PF01048 0.721
MOD_GlcNHglycan 433 437 PF01048 0.645
MOD_GlcNHglycan 474 477 PF01048 0.691
MOD_GlcNHglycan 535 538 PF01048 0.658
MOD_GlcNHglycan 66 70 PF01048 0.701
MOD_GlcNHglycan 76 79 PF01048 0.517
MOD_GSK3_1 188 195 PF00069 0.690
MOD_GSK3_1 24 31 PF00069 0.614
MOD_GSK3_1 247 254 PF00069 0.805
MOD_GSK3_1 292 299 PF00069 0.639
MOD_GSK3_1 302 309 PF00069 0.623
MOD_GSK3_1 329 336 PF00069 0.665
MOD_GSK3_1 349 356 PF00069 0.559
MOD_GSK3_1 360 367 PF00069 0.681
MOD_GSK3_1 388 395 PF00069 0.634
MOD_GSK3_1 400 407 PF00069 0.769
MOD_GSK3_1 464 471 PF00069 0.720
MOD_GSK3_1 49 56 PF00069 0.747
MOD_GSK3_1 5 12 PF00069 0.706
MOD_GSK3_1 532 539 PF00069 0.606
MOD_GSK3_1 70 77 PF00069 0.722
MOD_N-GLC_1 137 142 PF02516 0.592
MOD_N-GLC_1 364 369 PF02516 0.627
MOD_N-GLC_1 57 62 PF02516 0.554
MOD_NEK2_1 331 336 PF00069 0.596
MOD_NEK2_1 369 374 PF00069 0.612
MOD_NEK2_1 5 10 PF00069 0.594
MOD_NEK2_1 550 555 PF00069 0.753
MOD_NEK2_2 219 224 PF00069 0.589
MOD_NEK2_2 449 454 PF00069 0.604
MOD_NEK2_2 78 83 PF00069 0.571
MOD_NMyristoyl 1 7 PF02799 0.590
MOD_PIKK_1 232 238 PF00454 0.594
MOD_PK_1 194 200 PF00069 0.626
MOD_PKA_1 224 230 PF00069 0.673
MOD_PKA_1 560 566 PF00069 0.778
MOD_PKA_2 224 230 PF00069 0.712
MOD_PKA_2 276 282 PF00069 0.595
MOD_PKA_2 292 298 PF00069 0.535
MOD_PKA_2 372 378 PF00069 0.642
MOD_PKA_2 397 403 PF00069 0.613
MOD_PKA_2 472 478 PF00069 0.732
MOD_PKA_2 560 566 PF00069 0.611
MOD_PKA_2 86 92 PF00069 0.597
MOD_PKB_1 284 292 PF00069 0.601
MOD_Plk_1 137 143 PF00069 0.593
MOD_Plk_1 318 324 PF00069 0.570
MOD_Plk_2-3 120 126 PF00069 0.605
MOD_Plk_4 194 200 PF00069 0.587
MOD_Plk_4 318 324 PF00069 0.542
MOD_Plk_4 354 360 PF00069 0.614
MOD_Plk_4 449 455 PF00069 0.603
MOD_Plk_4 49 55 PF00069 0.582
MOD_Plk_4 78 84 PF00069 0.610
MOD_ProDKin_1 100 106 PF00069 0.686
MOD_ProDKin_1 169 175 PF00069 0.693
MOD_ProDKin_1 251 257 PF00069 0.666
MOD_ProDKin_1 339 345 PF00069 0.625
MOD_ProDKin_1 350 356 PF00069 0.563
MOD_ProDKin_1 364 370 PF00069 0.511
MOD_ProDKin_1 380 386 PF00069 0.704
MOD_ProDKin_1 414 420 PF00069 0.663
MOD_ProDKin_1 53 59 PF00069 0.653
MOD_ProDKin_1 569 575 PF00069 0.606
MOD_ProDKin_1 579 585 PF00069 0.552
MOD_ProDKin_1 6 12 PF00069 0.593
MOD_ProDKin_1 70 76 PF00069 0.706
MOD_ProDKin_1 93 99 PF00069 0.600
MOD_SUMO_for_1 465 468 PF00179 0.606
MOD_SUMO_rev_2 518 528 PF00179 0.599
TRG_ER_diArg_1 223 225 PF00400 0.778
TRG_ER_diArg_1 249 252 PF00400 0.630
TRG_ER_diArg_1 260 263 PF00400 0.531
TRG_ER_diArg_1 560 562 PF00400 0.601
TRG_Pf-PMV_PEXEL_1 427 431 PF00026 0.661

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8ISS4 Leishmania donovani 98% 100%
E9B220 Leishmania mexicana (strain MHOM/GT/2001/U1103) 70% 99%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS