LeishMANIAdb
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Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Protein kinase domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I6Z7_LEIIN
TriTrypDb:
LINF_310030000
Length:
903

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I6Z7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I6Z7

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 568 572 PF00656 0.747
CLV_C14_Caspase3-7 792 796 PF00656 0.618
CLV_NRD_NRD_1 128 130 PF00675 0.636
CLV_NRD_NRD_1 151 153 PF00675 0.835
CLV_NRD_NRD_1 195 197 PF00675 0.805
CLV_NRD_NRD_1 323 325 PF00675 0.574
CLV_NRD_NRD_1 351 353 PF00675 0.630
CLV_NRD_NRD_1 37 39 PF00675 0.556
CLV_NRD_NRD_1 444 446 PF00675 0.799
CLV_NRD_NRD_1 467 469 PF00675 0.650
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IIP7 Leishmania donovani 99% 100%
A4HJK0 Leishmania braziliensis 48% 100%
E9B218 Leishmania mexicana (strain MHOM/GT/2001/U1103) 73% 95%
Q4Q643 Leishmania major 81% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS