Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I6Y5_LEIIN

TriTrypDb:

LINF_310028750

Length:

158

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I6Y5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I6Y5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	67	71	PF00656	0.498
CLV_C14_Caspase3-7	83	87	PF00656	0.499
CLV_NRD_NRD_1	89	91	PF00675	0.305
CLV_NRD_NRD_1	96	98	PF00675	0.316
CLV_PCSK_KEX2_1	89	91	PF00082	0.305
CLV_PCSK_KEX2_1	95	97	PF00082	0.319
CLV_PCSK_SKI1_1	101	105	PF00082	0.199
CLV_PCSK_SKI1_1	89	93	PF00082	0.309
DEG_APCC_DBOX_1	100	108	PF00400	0.400
DOC_CDC14_PxL_1	105	113	PF14671	0.199
DOC_CYCLIN_RxL_1	95	106	PF00134	0.513
DOC_PP2B_LxvP_1	25	28	PF13499	0.363
DOC_PP4_FxxP_1	110	113	PF00568	0.199
DOC_USP7_MATH_1	19	23	PF00917	0.382
DOC_USP7_MATH_1	9	13	PF00917	0.368
DOC_USP7_MATH_1	99	103	PF00917	0.513
DOC_WW_Pin1_4	122	127	PF00397	0.370
DOC_WW_Pin1_4	146	151	PF00397	0.348
DOC_WW_Pin1_4	7	12	PF00397	0.366
LIG_Actin_WH2_2	113	130	PF00022	0.199
LIG_BIR_II_1	1	5	PF00653	0.377
LIG_Clathr_ClatBox_1	75	79	PF01394	0.539
LIG_LIR_Apic_2	12	18	PF02991	0.378
LIG_LIR_Gen_1	40	51	PF02991	0.199
LIG_LIR_Nem_3	40	46	PF02991	0.199
LIG_LIR_Nem_3	50	56	PF02991	0.199
LIG_MYND_1	109	113	PF01753	0.199
LIG_SH2_CRK	15	19	PF00017	0.382
LIG_SH2_CRK	53	57	PF00017	0.351
LIG_SH2_NCK_1	15	19	PF00017	0.382
LIG_SH2_STAT5	55	58	PF00017	0.509
LIG_SH3_3	148	154	PF00018	0.349
LIG_SH3_3	8	14	PF00018	0.368
LIG_SUMO_SIM_par_1	112	118	PF11976	0.199
LIG_SUMO_SIM_par_1	74	79	PF11976	0.538
LIG_TYR_ITIM	51	56	PF00017	0.199
MOD_CDC14_SPxK_1	125	128	PF00782	0.323
MOD_CDC14_SPxK_1	149	152	PF00782	0.351
MOD_CDK_SPxK_1	122	128	PF00069	0.372
MOD_CDK_SPxK_1	146	152	PF00069	0.348
MOD_CDK_SPxxK_3	10	17	PF00069	0.375
MOD_CK1_1	140	146	PF00069	0.318
MOD_CK1_1	33	39	PF00069	0.199
MOD_CK1_1	5	11	PF00069	0.365
MOD_GlcNHglycan	117	120	PF01048	0.199
MOD_GlcNHglycan	21	24	PF01048	0.582
MOD_GlcNHglycan	25	28	PF01048	0.563
MOD_GlcNHglycan	30	33	PF01048	0.559
MOD_GSK3_1	136	143	PF00069	0.301
MOD_GSK3_1	19	26	PF00069	0.381
MOD_GSK3_1	33	40	PF00069	0.199
MOD_GSK3_1	42	49	PF00069	0.199
MOD_GSK3_1	5	12	PF00069	0.366
MOD_GSK3_1	99	106	PF00069	0.512
MOD_NEK2_1	103	108	PF00069	0.199
MOD_NEK2_1	115	120	PF00069	0.199
MOD_NEK2_1	137	142	PF00069	0.299
MOD_NEK2_1	30	35	PF00069	0.353
MOD_NEK2_1	38	43	PF00069	0.199
MOD_NEK2_1	46	51	PF00069	0.199
MOD_PIKK_1	152	158	PF00454	0.348
MOD_Plk_2-3	65	71	PF00069	0.499
MOD_Plk_4	103	109	PF00069	0.199
MOD_Plk_4	33	39	PF00069	0.199
MOD_Plk_4	42	48	PF00069	0.199
MOD_Plk_4	56	62	PF00069	0.508
MOD_Plk_4	68	74	PF00069	0.508
MOD_ProDKin_1	122	128	PF00069	0.372
MOD_ProDKin_1	146	152	PF00069	0.348
MOD_ProDKin_1	7	13	PF00069	0.367
TRG_DiLeu_BaLyEn_6	110	115	PF01217	0.199
TRG_DiLeu_BaLyEn_6	71	76	PF01217	0.521
TRG_ENDOCYTIC_2	53	56	PF00928	0.357
TRG_ER_diArg_1	88	90	PF00400	0.513
TRG_ER_diArg_1	94	97	PF00400	0.511
TRG_Pf-PMV_PEXEL_1	96	100	PF00026	0.318